Small-molecule inhibitors of protein-protein interactions: progressing toward the reality MR Arkin, Y Tang, JA Wells Chemistry & biology 21 (9), 1102-1114, 2014 | 1139 | 2014 |
Structure and mechanism of the 6-deoxyerythronolide B synthase C Khosla, Y Tang, AY Chen, NA Schnarr, DE Cane Annu. Rev. Biochem. 76, 195-221, 2007 | 362 | 2007 |
The 2.7-Å crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase Y Tang, CY Kim, II Mathews, DE Cane, C Khosla Proceedings of the National Academy of Sciences 103 (30), 11124-11129, 2006 | 350 | 2006 |
Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase Y Tang, AY Chen, CY Kim, DE Cane, C Khosla Chemistry & biology 14 (8), 931-943, 2007 | 206 | 2007 |
Heterologous expression, purification, refolding, and structural-functional characterization of EP-B2, a self-activating barley cysteine endoprotease MT Bethune, P Strop, Y Tang, LM Sollid, C Khosla Chemistry & biology 13 (6), 637-647, 2006 | 147 | 2006 |
Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase CY Kim, VY Alekseyev, AY Chen, Y Tang, DE Cane, C Khosla Biochemistry 43 (44), 13892-13898, 2004 | 90 | 2004 |
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy X Chen, Y Li, C Wang, Y Tang, SA Mok, RM Tsai, JC Rojas, A Karydas, ... Molecular neurodegeneration 15, 1-19, 2020 | 76 | 2020 |
Mechanistic and structural understanding of uncompetitive inhibitors of caspase-6 CE Heise, J Murray, KE Augustyn, B Bravo, P Chugha, F Cohen, ... PLoS One 7 (12), e50864, 2012 | 44 | 2012 |
Structural and Functional Studies on SCO1815: A β-Ketoacyl-Acyl Carrier Protein Reductase from Streptomyces coelicolor A3(2) Y Tang, HY Lee, Y Tang, CY Kim, I Mathews, C Khosla Biochemistry 45 (47), 14085-14093, 2006 | 39 | 2006 |
Mechanism based protein crosslinking of domains from the 6-deoxyerythronolide B synthase S Kapur, A Worthington, Y Tang, DE Cane, MD Burkart, C Khosla Bioorganic & medicinal chemistry letters 18 (10), 3034-3038, 2008 | 38 | 2008 |
Tailoring Small Molecules for an Allosteric Site on Procaspase‐6 J Murray, AM Giannetti, M Steffek, P Gibbons, BR Hearn, F Cohen, C Tam, ... ChemMedChem 9 (1), 73-77, 2014 | 33 | 2014 |
Structural and enzymatic insights into caspase-2 protein substrate recognition and catalysis Y Tang, JA Wells, MR Arkin Journal of Biological Chemistry 286 (39), 34147-34154, 2011 | 33 | 2011 |
UCSF Small Molecule Discovery Center: innovation, collaboration and chemical biology in the Bay Area M R Arkin, K KH Ang, S Chen, J Davies, C Merron, Y Tang, C GM Wilson, ... Combinatorial Chemistry & High Throughput Screening 17 (4), 333-342, 2014 | 11 | 2014 |
改性高岭土性能的研究 王栋, 唐玉龙, 刘涛, 翟佳宁, 孙树明, 陆通 工业催化 22 (2), 128-131, 2014 | 10 | 2014 |
镁合金直接化学镀 Ni-B 镀层的腐蚀电化学行为研究 彭淑合, 贾飞, 唐毅, 王周成 腐蚀科学与防护技术 21 (2), 191-193, 2009 | 9 | 2009 |
Isolation and identification of steroidal saponins from Dioscorea panthaica Prain et Burkill. BG Li, YF Tang, Y Shi | 7 | 1986 |
Engaging a non-catalytic cysteine Residue drives potent and selective inhibition of Caspase-6 KS Van Horn, D Wang, D Medina-Cleghorn, PS Lee, C Bryant, C Altobelli, ... Journal of the American Chemical Society 145 (18), 10015-10021, 2023 | 5 | 2023 |
LC3B Binds to the Autophagy Protease ATG4b with High Affinity Using a Bipartite Interface Y Tang, A Kay, Z Jiang, MR Arkin Biochemistry 61 (21), 2295-2302, 2022 | 2 | 2022 |
Engaging a non-catalytic cysteine residue drives unprecedented selectivity of caspase inhibition K Van Horn, D Wang, D Medina-Cleghorn, P Lee, C Bryant, C Altobelli, ... | 1 | 2022 |
Tau Secretion and Propagation Is Regulated by p300/CBP via Autophagy-Lysosomal Pathway in Tauopathy X Chen, Y Li, C Wang, Y Tang, SA Mok, RM Tsai, JC Rojas, A Karydas, ... bioRxiv, 418640, 2018 | 1 | 2018 |