| ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids KR Bowles, MC Silva, K Whitney, T Bertucci, JE Berlind, JD Lai, JC Garza, ... Cell 184 (17), 4547-4563. e17, 2021 | 95 | 2021 |
| The endothelial cell receptor stabilin-2 regulates VWF-FVIII complex half-life and immunogenicity LL Swystun, JD Lai, C Notley, I Georgescu, AS Paine, J Mewburn, ... The Journal of clinical investigation 128 (9), 4057-4073, 2018 | 72 | 2018 |
| Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons Y Shi, ST Hung, G Rocha, S Lin, GR Linares, KA Staats, C Seah, Y Wang, ... JCI insight 4 (15), 2019 | 52 | 2019 |
| Biological considerations of plasma-derived and recombinant factor VIII immunogenicity J Lai, C Hough, J Tarrant, D Lillicrap Blood, The Journal of the American Society of Hematology 129 (24), 3147-3154, 2017 | 48 | 2017 |
| The endothelial lectin clearance receptor CLEC4M binds and internalizes factor VIII in a VWF‐dependent and independent manner LL Swystun, C Notley, I Georgescu, JD Lai, K Nesbitt, PD James, ... Journal of Thrombosis and Haemostasis 17 (4), 681-694, 2019 | 44 | 2019 |
| PIKFYVE inhibition mitigates disease in models of diverse forms of ALS ST Hung, GR Linares, WH Chang, Y Eoh, G Krishnan, S Mendonca, ... Cell 186 (4), 786-802. e28, 2023 | 37 | 2023 |
| Factor VIII inhibitors: advances in basic and translational science JD Lai, D Lillicrap International Journal of Laboratory Hematology 39, 6-13, 2017 | 37 | 2017 |
| Concurrent influenza vaccination reduces anti-FVIII antibody responses in murine hemophilia A JD Lai, PC Moorehead, K Sponagle, KN Steinitz, BM Reipert, C Hough, ... Blood, The Journal of the American Society of Hematology 127 (26), 3439-3449, 2016 | 34 | 2016 |
| N-linked glycosylation modulates the immunogenicity of recombinant human factor VIII in hemophilia A mice JD Lai, LL Swystun, D Cartier, K Nesbitt, C Zhang, C Hough, JW Dennis, ... Haematologica 103 (11), 1925, 2018 | 29 | 2018 |
| C9ORF72 protein function and immune dysregulation in amyotrophic lateral sclerosis JD Lai, JK Ichida Neuroscience Letters 713, 134523, 2019 | 28 | 2019 |
| The scavenger receptor SCARA5 is an endocytic receptor for von Willebrand factor expressed by littoral cells in the human spleen LL Swystun, K Ogiwara, JD Lai, JRM Ojala, O Rawley, F Lassalle, ... Journal of Thrombosis and Haemostasis 17 (8), 1384-1396, 2019 | 24 | 2019 |
| Early cellular interactions and immune transcriptome profiles in human factor VIII‐exposed hemophilia A mice JD Lai, D Cartier, RB Hartholt, LL Swystun, AS Van Velzen, ... Journal of Thrombosis and Haemostasis 16 (3), 533-545, 2018 | 22 | 2018 |
| War and peace: factor VIII and the adaptive immune response MT Georgescu, JD Lai, C Hough, D Lillicrap Cellular Immunology 301, 2-7, 2016 | 21 | 2016 |
| Genetic connectivity across marginal habitats: the elephants of the Namib Desert Y Ishida, PJ Van Coeverden de Groot, KEA Leggett, AS Putnam, VE Fox, ... Ecology and Evolution 6 (17), 6189-6201, 2016 | 20 | 2016 |
| To clear or to fear: An innate perspective on factor VIII immunity JD Lai, MT Georgescu, C Hough, D Lillicrap Cellular Immunology 301, 82-89, 2016 | 20 | 2016 |
| KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injury JD Lai, JE Berlind, G Fricklas, C Lie, JP Urenda, K Lam, NS Maria, ... Cell Stem Cell 31 (4), 519-536. e8, 2024 | 8* | 2024 |
