| Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory GM Shankar, S Li, TH Mehta, A Garcia-Munoz, NE Shepardson, I Smith, ... Nature medicine 14 (8), 837-842, 2008 | 4457 | 2008 |
| Natural oligomers of the amyloid-β protein specifically disrupt cognitive function JP Cleary, DM Walsh, JJ Hofmeister, GM Shankar, MA Kuskowski, ... Nature neuroscience 8 (1), 79-84, 2005 | 2238 | 2005 |
| Natural oligomers of the Alzheimer amyloid-β protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway GM Shankar, BL Bloodgood, M Townsend, DM Walsh, DJ Selkoe, ... Journal of Neuroscience 27 (11), 2866-2875, 2007 | 2035 | 2007 |
| Soluble oligomers of amyloid β protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake S Li, S Hong, NE Shepardson, DM Walsh, GM Shankar, D Selkoe Neuron 62 (6), 788-801, 2009 | 1164 | 2009 |
| Effects of secreted oligomers of amyloid β‐protein on hippocampal synaptic plasticity: a potent role for trimers M Townsend, GM Shankar, T Mehta, DM Walsh, DJ Selkoe The Journal of physiology 572 (2), 477-492, 2006 | 823 | 2006 |
| Soluble Aβ oligomers inhibit long-term potentiation through a mechanism involving excessive activation of extrasynaptic NR2B-containing NMDA receptors S Li, M Jin, T Koeglsperger, NE Shepardson, GM Shankar, DJ Selkoe Journal of Neuroscience 31 (18), 6627-6638, 2011 | 770 | 2011 |
| Protein aggregation in the brain: the molecular basis for Alzheimer’s and Parkinson’s diseases GB Irvine, OM El-Agnaf, GM Shankar, DM Walsh Molecular medicine 14, 451-464, 2008 | 705 | 2008 |
| Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo I Klyubin, DM Walsh, CA Lemere, WK Cullen, GM Shankar, V Betts, ... Nature medicine 11 (5), 556-561, 2005 | 694 | 2005 |
| Alzheimer's disease: synaptic dysfunction and Aβ GM Shankar, DM Walsh Molecular neurodegeneration 4, 1-13, 2009 | 633 | 2009 |
| Certain inhibitors of synthetic amyloid β-peptide (Aβ) fibrillogenesis block oligomerization of natural Aβ and thereby rescue long-term potentiation DM Walsh, M Townsend, MB Podlisny, GM Shankar, JV Fadeeva, ... Journal of Neuroscience 25 (10), 2455-2462, 2005 | 402 | 2005 |
| The presence of sodium dodecyl sulphate-stable Aβ dimers is strongly associated with Alzheimer-type dementia JM Mc Donald, GM Savva, C Brayne, AT Welzel, G Forster, GM Shankar, ... Brain 133 (5), 1328-1341, 2010 | 323 | 2010 |
| The role of cell-derived oligomers of Aβ in Alzheimer's disease and avenues for therapeutic intervention DM Walsh, I Klyubin, GM Shankar, M Townsend, JV Fadeeva, V Betts, ... Biochemical Society Transactions 33 (5), 1087-1090, 2005 | 305 | 2005 |
| Cholesterol level and statin use in Alzheimer disease: I. Review of epidemiological and preclinical studies NE Shepardson, GM Shankar, DJ Selkoe Archives of neurology 68 (10), 1239-1244, 2011 | 290 | 2011 |
| A specific enzyme-linked immunosorbent assay for measuring β-amyloid protein oligomers in human plasma and brain tissue of patients with Alzheimer disease W Xia, T Yang, G Shankar, IM Smith, Y Shen, DM Walsh, DJ Selkoe Archives of neurology 66 (2), 190-199, 2009 | 263 | 2009 |
| Dramatic response of BRAF V600E mutant papillary craniopharyngioma to targeted therapy PK Brastianos, GM Shankar, CM Gill, A Taylor-Weiner, N Nayyar, ... Journal of the National Cancer Institute 108 (2), djv310, 2016 | 224 | 2016 |
| Cholesterol level and statin use in Alzheimer disease: II. Review of human trials and recommendations NE Shepardson, GM Shankar, DJ Selkoe Archives of neurology 68 (11), 1385-1392, 2011 | 217 | 2011 |
| Loss of neprilysin function promotes amyloid plaque formation and causes cerebral amyloid angiopathy W Farris, SG Schütz, JR Cirrito, GM Shankar, X Sun, A George, ... The American journal of pathology 171 (1), 241-251, 2007 | 210 | 2007 |
| Germline and somatic BAP1 mutations in high-grade rhabdoid meningiomas GM Shankar, M Abedalthagafi, RA Vaubel, PH Merrill, N Nayyar, CM Gill, ... Neuro-oncology 19 (4), 535-545, 2017 | 188 | 2017 |
| Complement component C3 and complement receptor type 3 contribute to the phagocytosis and clearance of fibrillar Aβ by microglia H Fu, B Liu, JL Frost, S Hong, M Jin, B Ostaszewski, GM Shankar, ... Glia 60 (6), 993-1003, 2012 | 187 | 2012 |
| Liquid biopsy for brain tumors GM Shankar, L Balaj, SL Stott, B Nahed, BS Carter Expert review of molecular diagnostics 17 (10), 943-947, 2017 | 159 | 2017 |
