Identification of a hormonal basis for gallbladder filling M Choi, A Moschetta, AL Bookout, L Peng, M Umetani, SR Holmstrom, ... Nature medicine 12 (11), 1253-1255, 2006 | 350 | 2006 |
The G protein-coupled bile acid receptor, TGR5, stimulates gallbladder filling T Li, SR Holmstrom, S Kir, M Umetani, DR Schmidt, SA Kliewer, ... Molecular endocrinology 25 (6), 1066-1071, 2011 | 272 | 2011 |
Regulation of bile acid synthesis by fat-soluble vitamins A and D DR Schmidt, SR Holmstrom, KF Tacer, AL Bookout, SA Kliewer, ... Journal of Biological Chemistry 285 (19), 14486-14494, 2010 | 246 | 2010 |
Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice Y Zhang, SR Breevoort, J Angdisen, M Fu, DR Schmidt, SR Holmstrom, ... The Journal of clinical investigation 122 (5), 1688-1699, 2012 | 237 | 2012 |
Direct and distinguishable inhibitory roles for SUMO isoforms in the control of transcriptional synergy S Holmstrom, ME Van Antwerp, JA Iñiguez-Lluhí Proceedings of the National Academy of Sciences 100 (26), 15758-15763, 2003 | 184 | 2003 |
Experimental microdissection enables functional harmonisation of pancreatic cancer subtypes C Maurer, SR Holmstrom, J He, P Laise, T Su, A Ahmed, H Hibshoosh, ... Gut 68 (6), 1034-1043, 2019 | 181 | 2019 |
LRH-1 and PTF1-L coregulate an exocrine pancreas-specific transcriptional network for digestive function SR Holmstrom, T Deering, GH Swift, FJ Poelwijk, DJ Mangelsdorf, ... Genes & development 25 (16), 1674-1679, 2011 | 133 | 2011 |
Role of TGR5 (GPBAR1) in liver disease V Keitel, D Häussinger Seminars in liver disease 38 (04), 333-339, 2018 | 88 | 2018 |
A small conserved surface in SUMO is the critical structural determinant of its transcriptional inhibitory properties S Chupreta, S Holmstrom, L Subramanian, JA Iñiguez-Lluhí Molecular and cellular biology 25 (10), 4272-4282, 2005 | 85 | 2005 |
SUMO-mediated inhibition of glucocorticoid receptor synergistic activity depends on stable assembly at the promoter but not on DAXX SR Holmstrom, S Chupreta, AYL So, JA Iñiguez-Lluhí Molecular endocrinology 22 (9), 2061-2075, 2008 | 70 | 2008 |
AKR1B7 is induced by the farnesoid X receptor and metabolizes bile acids DR Schmidt, S Schmidt, SR Holmstrom, M Makishima, TY Ruth, ... Journal of Biological Chemistry 286 (4), 2425-2432, 2011 | 45 | 2011 |
Effect of the antimalarial drug halofantrine in the long QT syndrome due to a mutation of the cardiac sodium channel gene SCN5A K Piippo, S Holmström, H Swan, M Viitasalo, M Raatikka, L Toivonen, ... American Journal of Cardiology 87 (7), 909-911, 2001 | 29 | 2001 |
Deficiency of the endocytic protein Hip1 leads to decreased Gdpd3 expression, low phosphocholine, and kypholordosis R Wijayatunge, SR Holmstrom, SB Foley, VE Mgbemena, V Bhargava, ... Molecular and cellular biology, 2018 | 9 | 2018 |
Protein breakdown precedes pancreatic tumor development SR Holmstrom, KP Olive Nature Medicine 20 (10), 1097-1099, 2014 | 8 | 2014 |
Functional interaction of BRCA1 and CREBBP in murine hematopoiesis SR Holmstrom, R Wijayatunge, K McCrum, VE Mgbemena, TS Ross Iscience 19, 809-820, 2019 | 5 | 2019 |
Transcriptional deconvolution reveals consistent functional subtypes of pancreatic cancer epithelium and stroma J He, HC Maurer, SR Holmstrom, T Su, A Ahmed, H Hibshoosh, ... bioRxiv, 288779, 2018 | 4 | 2018 |
Ras-dependent activation of BMAL2 regulates hypoxic metabolism in pancreatic cancer HC Maurer, A Curiel-Garcia, S Holmstrom, P Laise, CF Palermo, ... bioRxiv, 2023 | 1 | 2023 |
Abstract IA16: Reconstructing compartment− specific regulatory programs in pancreatic cancer HC Maurer, J He, MJ Alvarez, F Giorgi, S Holmstrom, A Califano, KP Olive Cancer Research 76 (24_Supplement), IA16-IA16, 2016 | 1 | 2016 |
BMAL2 is a KRAS-dependent master regulator of hypoxic response in pancreatic ductal adenocarcinoma AC Garcia, CH Maurer, K Hollinshead, P Laise, A Andren, SA Sastra, ... Cancer Research 83 (7_Supplement), 4803-4803, 2023 | | 2023 |
BRCA1 and TP53 codeficiency causes a PARP inhibitor–sensitive erythroproliferative neoplasm G Lopez-Perez, R Wijayatunge, KB McCrum, SR Holmstrom, ... JCI insight 7 (24), 2022 | | 2022 |