HER2-Mediated Internalization of Cytotoxic Agents in ERBB2 Amplified or Mutant Lung Cancers BT Li, F Michelini, S Misale, E Cocco, L Baldino, Y Cai, S Shifman, HY Tu, ... Cancer discovery 10 (5), 674-687, 2020 | 190 | 2020 |
Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer JJ Tao, P Castel, N Radosevic-Robin, M Elkabets, N Auricchio, N Aceto, ... Science signaling 7 (318), ra29-ra29, 2014 | 168 | 2014 |
ALIX regulates tumor-mediated immunosuppression by controlling EGFR activity and PD-L1 presentation J Monypenny, H Milewicz, F Flores-Borja, G Weitsman, A Cheung, ... Cell reports 24 (3), 630-641, 2018 | 122 | 2018 |
Proapoptotic kinase MST2 coordinates signaling crosstalk between RASSF1A, Raf-1, and Akt D Romano, D Matallanas, G Weitsman, C Preisinger, T Ng, W Kolch Cancer research 70 (3), 1195-1203, 2010 | 116 | 2010 |
Estrogen Receptor-α Phosphorylated at Ser118 Is Present at the Promoters of Estrogen-Regulated Genes and Is Not Altered Due to HER-2 Overexpression GE Weitsman, L Li, GP Skliris, JR Davie, K Ung, Y Niu, L Curtis-Snell, ... Cancer research 66 (20), 10162-10170, 2006 | 111 | 2006 |
Vitamin D enhances caspase‐dependent and‐independent TNFα‐induced breast cancer cell death: The role of reactive oxygen species and mitochondria GE Weitsman, A Ravid, UA Liberman, R Koren International journal of cancer 106 (2), 178-186, 2003 | 72 | 2003 |
Vitamin D sensitizes breast cancer cells to the action of H2O2: mitochondria as a convergence point in the death pathway GE Weitsman, R Koren, E Zuck, C Rotem, UA Liberman, A Ravid Free Radical Biology and Medicine 39 (2), 266-278, 2005 | 67 | 2005 |
Ado-trastuzumab emtansine in patients with HER2 amplified salivary gland cancers (SGCs): Results from a phase II basket trial. BT Li, R Shen, M Offin, DJ Buonocore, ML Myers, A Venkatesh, P Razavi, ... Journal of Clinical Oncology 37 (15_suppl), 6001-6001, 2019 | 64 | 2019 |
Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface J Claus, G Patel, F Autore, A Colomba, G Weitsman, TN Soliman, ... Elife 7, e32271, 2018 | 62 | 2018 |
How Förster resonance energy transfer imaging improves the understanding of protein interaction networks in cancer biology GO Fruhwirth, LP Fernandes, G Weitsman, G Patel, M Kelleher, K Lawler, ... ChemPhysChem 12 (3), 442-461, 2011 | 62 | 2011 |
Assessment of multiple different estrogen receptor-β antibodies for their ability to immunoprecipitate under chromatin immunoprecipitation conditions GE Weitsman, G Skliris, K Ung, B Peng, M Younes, PH Watson, ... Breast cancer research and treatment 100, 23-31, 2006 | 57 | 2006 |
From autoinhibition to inhibition in trans: the Raf-1 regulatory domain inhibits Rok-α kinase activity T Niault, I Sobczak, K Meissl, G Weitsman, D Piazzolla, G Maurer, F Kern, ... Journal of Cell Biology 187 (3), 335-342, 2009 | 55 | 2009 |
Potential role of estrogen receptor α (ERα) phosphorylated at Serine118 in human breast cancer in vivo LC Murphy, GE Weitsman, GP Skliris, EM Teh, L Li, B Peng, JR Davie, ... The Journal of steroid biochemistry and molecular biology 102 (1-5), 139-146, 2006 | 53 | 2006 |
Effect of phosphorylation on EGFR dimer stability probed by single-molecule dynamics and FRET/FLIM O Coban, LC Zanetti-Dominguez, DR Matthews, DJ Rolfe, G Weitsman, ... Biophysical journal 108 (5), 1013-1026, 2015 | 52 | 2015 |
Time‐domain microfluidic fluorescence lifetime flow cytometry for high‐throughput F örster resonance energy transfer screening J Nedbal, V Visitkul, E Ortiz‐Zapater, G Weitsman, P Chana, DR Matthews, ... Cytometry Part A 87 (2), 104-118, 2015 | 43 | 2015 |
A multi-functional imaging approach to high-content protein interaction screening DR Matthews, GO Fruhwirth, G Weitsman, LM Carlin, E Ofo, M Keppler, ... PloS one 7 (4), e33231, 2012 | 42 | 2012 |
Vitamin D enhances caspase‐dependent and independent TNF‐induced breast cancer cell death: the role of reactive oxygen species GE Weitsman, A Ravid, UA Liberman, R Koren Annals of the New York Academy of Sciences 1010 (1), 437-440, 2003 | 42 | 2003 |
HER2-HER3 dimer quantification by FLIM-FRET predicts breast cancer metastatic relapse independently of HER2 IHC status G Weitsman, PR Barber, LK Nguyen, K Lawler, G Patel, N Woodman, ... Oncotarget 7 (32), 51012, 2016 | 38 | 2016 |
Reactive oxygen species induce phosphorylation of serine 118 and 167 on estrogen receptor alpha GE Weitsman, W Weebadda, K Ung, LC Murphy Breast cancer research and treatment 118, 269-279, 2009 | 35 | 2009 |
Feedback activation of HER3 attenuates response to EGFR inhibitors in colon cancer cells A Bosch-Vilaró, B Jacobs, V Pomella, LA Asbagh, R Kirkland, J Michel, ... Oncotarget 8 (3), 4277, 2017 | 32 | 2017 |