Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme JM White, SE Delos, M Brecher, K Schornberg Critical reviews in biochemistry and molecular biology 43 (3), 189-219, 2008 | 1066 | 2008 |
Influenza virus pleiomorphy characterized by cryoelectron tomography A Harris, G Cardone, DC Winkler, JB Heymann, M Brecher, JM White, ... Proceedings of the National Academy of Sciences 103 (50), 19123-19127, 2006 | 617 | 2006 |
Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction Z Li, M Brecher, YQ Deng, J Zhang, S Sakamuru, B Liu, R Huang, ... Cell research 27 (8), 1046-1064, 2017 | 202 | 2017 |
Cathepsin cleavage potentiates the Ebola virus glycoprotein to undergo a subsequent fusion-relevant conformational change M Brecher, KL Schornberg, SE Delos, ML Fusco, EO Saphire, JM White Journal of virology 86 (1), 364-372, 2012 | 193 | 2012 |
The primed ebolavirus glycoprotein (19-kilodalton GP1, 2): sequence and residues critical for host cell binding D Dube, MB Brecher, SE Delos, SC Rose, EW Park, KL Schornberg, ... Journal of virology 83 (7), 2883-2891, 2009 | 193 | 2009 |
Effects of Zika Virus Strain and Aedes Mosquito Species on Vector Competence. KLD Ciota AT, Bialosuknia SM, Zink SD, Brecher M, Ehrbar DJ, Morrissette MN Emerging Infectious Diseases 23 (7), 1110-1117, 2017 | 155 | 2017 |
A conformational switch high-throughput screening assay and allosteric inhibition of the flavivirus NS2B-NS3 protease M Brecher, Z Li, B Liu, J Zhang, CA Koetzner, A Alifarag, SA Jones, Q Lin, ... PLoS pathogens 13 (5), e1006411, 2017 | 144 | 2017 |
Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease Z Li, S Sakamuru, R Huang, M Brecher, CA Koetzner, J Zhang, H Chen, ... Antiviral research 150, 217-225, 2018 | 74 | 2018 |
Novel broad spectrum inhibitors targeting the flavivirus methyltransferase M Brecher, H Chen, B Liu, NK Banavali, SA Jones, J Zhang, Z Li, ... PLoS One 10 (6), e0130062, 2015 | 67 | 2015 |
The flavivirus protease as a target for drug discovery M Brecher, J Zhang, H Li Virologica Sinica 28, 326-336, 2013 | 63 | 2013 |
Identification and characterization of novel broad-spectrum inhibitors of the flavivirus methyltransferase M Brecher, H Chen, Z Li, NK Banavali, SA Jones, J Zhang, LD Kramer, ... ACS infectious diseases 1 (8), 340-349, 2015 | 62 | 2015 |
DNA forms of arboviral RNA genomes are generated following infection in mosquito cell cultures DK Nag, M Brecher, LD Kramer Virology 498, 164-171, 2016 | 47 | 2016 |
S-adenosyl-homocysteine is a weakly bound inhibitor for a flaviviral methyltransferase H Chen, B Zhou, M Brecher, N Banavali, SA Jones, Z Li, J Zhang, D Nag, ... PLoS One 8 (10), e76900, 2013 | 25 | 2013 |
Coupling of conformational transitions in the N-terminal domain of the 51-kDa FK506-binding protein (FKBP51) near its site of interaction with the steroid receptor proteins DM LeMaster, SM Mustafi, M Brecher, J Zhang, A Héroux, H Li, ... Journal of Biological Chemistry 290 (25), 15746-15757, 2015 | 24 | 2015 |
Visualization of the two-step fusion process of the retrovirus avian sarcoma/leukosis virus by cryo-electron tomography G Cardone, M Brecher, J Fontana, DC Winkler, C Butan, JM White, ... Journal of virology 86 (22), 12129-12137, 2012 | 24 | 2012 |
Cysteines flanking the internal fusion peptide are required for the avian sarcoma/leukosis virus glycoprotein to mediate the lipid mixing stage of fusion with high efficiency SE Delos, MB Brecher, Z Chen, DC Melder, MJ Federspiel, JM White Journal of virology 82 (6), 3131-3134, 2008 | 24 | 2008 |
Refolding of a fully functional flavivirus methyltransferase revealed that S‐adenosyl methionine but not S‐adenosyl homocysteine is copurified with flavivirus methyltransferase MB Brecher, Z Li, J Zhang, H Chen, Q Lin, B Liu, H Li Protein Science 24 (1), 117-128, 2015 | 17 | 2015 |
Structural basis of conformational transitions in the active site and 80′ s loop in the FK506-binding protein FKBP12 SM Mustafi, M Brecher, J Zhang, H Li, DM Lemaster, G Hernández Biochemical Journal 458 (3), 525-536, 2014 | 15 | 2014 |
Extensive recoding of dengue virus type 2 specifically reduces replication in primate cells without gain-of-function in Aedes aegypti mosquitoes CB Stauft, SH Shen, Y Song, O Gorbatsevych, E Asare, B Futcher, ... PloS one 13 (9), e0198303, 2018 | 14 | 2018 |
Pfit Is a Structurally Novel Crohn's Disease-Associated Superantigen L Liu, H Chen, MB Brecher, Z Li, B Wei, B Nandi, J Zhang, H Ling, ... PLoS pathogens 9 (12), e1003837, 2013 | 4 | 2013 |