Palmitoylation targets the calcineurin phosphatase to the phosphatidylinositol 4-kinase complex at the plasma membrane I Ulengin-Talkish, MAH Parson, ML Jenkins, J Roy, AZL Shih, N St-Denis, ... Nature communications 12 (1), 6064, 2021 | 24 | 2021 |
Oncogenic mutations of PIK3CA lead to increased membrane recruitment driven by reorientation of the ABD, p85 and C-terminus ML Jenkins, H Ranga-Prasad, MAH Parson, NJ Harris, MK Rathinaswamy, ... Nature Communications 14 (1), 181, 2023 | 16 | 2023 |
A previously uncharacterized O-glycopeptidase from Akkermansia muciniphila requires the Tn-antigen for cleavage of the peptide bond BJ Medley, L Leclaire, N Thompson, KE Mahoney, B Pluvinage, ... Journal of Biological Chemistry 298 (10), 2022 | 14 | 2022 |
Biochemical insight into novel Rab-GEF activity of the mammalian TRAPPIII complex NJ Harris, ML Jenkins, U Dalwadi, KD Fleming, SE Nam, MAH Parson, ... Journal of Molecular Biology 433 (18), 167145, 2021 | 13 | 2021 |
Investigating how intrinsically disordered regions contribute to protein function using HDX-MS MAH Parson, ML Jenkins, JE Burke Biochemical Society Transactions 50 (6), 1607-1617, 2022 | 6 | 2022 |
Spartin-mediated lipid transfer facilitates lipid droplet turnover N Wan, Z Hong, MAH Parson, JL Korfhage, JE Burke, TJ Melia, ... Proceedings of the National Academy of Sciences 121 (3), e2314093121, 2024 | 5 | 2024 |
ATP-competitive and allosteric inhibitors induce differential conformational changes at the autoinhibitory interface of Akt1 AL Shaw, MAH Parson, L Truebestein, ML Jenkins, TA Leonard, JE Burke Structure 31 (3), 343-354. e3, 2023 | 5 | 2023 |
PKD autoinhibition in trans regulates activation loop autophosphorylation in cis R Reinhardt, K Hirzel, G Link, SA Eisler, T Hägele, MAH Parson, JE Burke, ... Proceedings of the National Academy of Sciences 120 (7), e2212909120, 2023 | 5 | 2023 |
Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11 MC Thibodeau, NJ Harris, ML Jenkins, MAH Parson, JT Evans, MK Scott, ... Journal of Biological Chemistry 299 (1), 2023 | 5 | 2023 |
ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages TA Bates, M Trank-Greene, X Nguyenla, A Anastas, SK Gurmessa, ... Elife 12, RP91930, 2024 | 3 | 2024 |
Allosteric activation or inhibition of PI3Kγ mediated through conformational changes in the p110γ helical domain NJ Harris, ML Jenkins, SE Nam, MK Rathinaswamy, MAH Parson, ... Elife 12, RP88058, 2023 | 1 | 2023 |
Molecular basis for plasma membrane recruitment of PI4KA by EFR3 S Suresh, AL Shaw, JG Pemberton, MK Scott, NJ Harris, MAH Parson, ... bioRxiv, 2024 | | 2024 |
Structure of calcineurin bound to PI4KA reveals dual interface in both PI4KA and FAM126A AL Shaw, S Suresh, MAH Parson, NJ Harris, ML Jenkins, CK Yip, ... Structure, 2024 | | 2024 |