A potential therapeutic role for angiotensin-converting enzyme 2 in human pulmonary arterial hypertension AR Hemnes, A Rathinasabapathy, EA Austin, EL Brittain, EJ Carrier, ... European Respiratory Journal 51 (6), 2018 | 218 | 2018 |
Fatty acid metabolic defects and right ventricular lipotoxicity in human pulmonary arterial hypertension EL Brittain, M Talati, JP Fessel, H Zhu, N Penner, MW Calcutt, JD West, ... Circulation 133 (20), 1936-1944, 2016 | 216 | 2016 |
Stimulation of host bone marrow stromal cells by sympathetic nerves promotes breast cancer bone metastasis in mice JP Campbell, MR Karolak, Y Ma, DS Perrien, SK Masood-Campbell, ... PLoS biology 10 (7), e1001363, 2012 | 197 | 2012 |
Evidence for right ventricular lipotoxicity in heritable pulmonary arterial hypertension AR Hemnes, EL Brittain, AW Trammell, JP Fessel, ED Austin, N Penner, ... American journal of respiratory and critical care medicine 189 (3), 325-334, 2014 | 181 | 2014 |
Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension AR Hemnes, AW Trammell, SL Archer, S Rich, C Yu, H Nian, N Penner, ... Circulation 131 (4), 401-409, 2015 | 95 | 2015 |
Mechanisms of lipid accumulation in the bone morphogenetic protein receptor type 2 mutant right ventricle MH Talati, EL Brittain, JP Fessel, N Penner, J Atkinson, M Funke, ... American journal of respiratory and critical care medicine 194 (6), 719-728, 2016 | 92 | 2016 |
Human PAH is characterized by a pattern of lipid-related insulin resistance AR Hemnes, JM Luther, CJ Rhodes, JP Burgess, J Carlson, R Fan, ... JCI insight 4 (1), 2019 | 87 | 2019 |
Endothelial HIF signaling regulates pulmonary fibrosis-associated pulmonary hypertension AJ Bryant, RP Carrick, ME McConaha, BR Jones, SD Shay, CS Moore, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 310 (3 …, 2016 | 80 | 2016 |
Testosterone negatively regulates right ventricular load stress responses in mice AR Hemnes, KB Maynard, HC Champion, L Gleaves, N Penner, J West, ... Pulmonary circulation 2 (3), 352-358, 2012 | 75 | 2012 |
Oxidative injury is a common consequence of BMPR2 mutations KL Lane, M Talati, E Austin, AR Hemnes, JA Johnson, JP Fessel, ... Pulmonary circulation 1 (1), 72-83, 2011 | 72 | 2011 |
Interaction between bone morphogenetic protein receptor type 2 and estrogenic compounds in pulmonary arterial hypertension JP Fessel, X Chen, A Frump, S Gladson, T Blackwell, C Kang, J Johnson, ... Pulmonary circulation 3 (3), 564-577, 2013 | 58 | 2013 |
Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension JP Fessel, CR Flynn, LJ Robinson, NL Penner, S Gladson, CJ Kang, ... American journal of respiratory cell and molecular biology 49 (5), 778-787, 2013 | 56 | 2013 |
Expression of mutant bone morphogenetic protein receptor II worsens pulmonary hypertension secondary to pulmonary fibrosis AJ Bryant, LJ Robinson, CS Moore, TR Blackwell, S Gladson, NL Penner, ... Pulmonary Circulation 5 (4), 681-690, 2015 | 38 | 2015 |
More than a biomarker: the systemic consequences of heparan sulfate fragments released during endothelial surface layer degradation (2017 Grover Conference Series) K Oshima, SM Haeger, JA Hippensteel, PS Herson, EP Schmidt Pulmonary circulation 8 (1), 2045893217745786, 2017 | 32 | 2017 |
Echocardiographic assessment of the right heart in mice E Brittain, NL Penner, J West, A Hemnes JoVE (Journal of Visualized Experiments), e50912, 2013 | 28 | 2013 |
BMPR2 dysfunction impairs insulin signaling and glucose homeostasis in cardiomyocytes AR Hemnes, JP Fessel, X Chen, S Zhu, NL Fortune, C Jetter, M Freeman, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 318 (2 …, 2020 | 25 | 2020 |
Natriuretic peptide receptor C contributes to disproportionate right ventricular hypertrophy in a rodent model of obesity-induced heart failure with preserved ejection fraction … V Agrawal, N Fortune, S Yu, J Fuentes, F Shi, D Nichols, L Gleaves, ... Pulmonary circulation 9 (4), 2045894019878599, 2019 | 25 | 2019 |
Bid maintains mitochondrial cristae structure and function and protects against cardiac disease in an integrative genomics study CT Salisbury-Ruf, CC Bertram, A Vergeade, DS Lark, Q Shi, ML Heberling, ... Elife 7, e40907, 2018 | 25 | 2018 |
Adverse physiologic effects of Western diet on right ventricular structure and function: role of lipid accumulation and metabolic therapy EL Brittain, M Talati, N Fortune, V Agrawal, DF Meoli, J West, AR Hemnes Pulmonary circulation 9 (1), 2045894018817741, 2018 | 23 | 2018 |
Pulmonary vascular effect of insulin in a rodent model of pulmonary arterial hypertension AW Trammell, M Talati, TR Blackwell, NL Fortune, KD Niswender, ... Pulmonary Circulation 7 (3), 624-634, 2017 | 21 | 2017 |