| Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression LS Qi, MH Larson, LA Gilbert, JA Doudna, JS Weissman, AP Arkin, ... Cell 152 (5), 1173-1183, 2013 | 5684 | 2013 |
| CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes LA Gilbert, MH Larson, L Morsut, Z Liu, GA Brar, SE Torres, ... Cell 154 (2), 442-451, 2013 | 4263 | 2013 |
| Genome-scale CRISPR-mediated control of gene repression and activation LA Gilbert, MA Horlbeck, B Adamson, JE Villalta, Y Chen, EH Whitehead, ... Cell 159 (3), 647-661, 2014 | 2795 | 2014 |
| Dynamic imaging of genomic loci in living human cells by an optimized CRISPR/Cas system B Chen, LA Gilbert, BA Cimini, J Schnitzbauer, W Zhang, GW Li, J Park, ... Cell 155 (7), 1479-1491, 2013 | 2213 | 2013 |
| A protein-tagging system for signal amplification in gene expression and fluorescence imaging ME Tanenbaum, LA Gilbert, LS Qi, JS Weissman, RD Vale Cell 159 (3), 635-646, 2014 | 1599 | 2014 |
| CRISPR interference (CRISPRi) for sequence-specific control of gene expression MH Larson, LA Gilbert, X Wang, WA Lim, JS Weissman, LS Qi Nature protocols 8 (11), 2180-2196, 2013 | 1402 | 2013 |
| Engineering complex synthetic transcriptional programs with CRISPR RNA scaffolds JG Zalatan, ME Lee, R Almeida, LA Gilbert, EH Whitehead, M La Russa, ... Cell 160 (1), 339-350, 2015 | 1077 | 2015 |
| A multiplexed single-cell CRISPR screening platform enables systematic dissection of the unfolded protein response B Adamson, TM Norman, M Jost, MY Cho, JK Nuñez, Y Chen, JE Villalta, ... Cell 167 (7), 1867-1882. e21, 2016 | 995 | 2016 |
| Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation MA Horlbeck, LA Gilbert, JE Villalta, B Adamson, RA Pak, Y Chen, ... elife 5, e19760, 2016 | 739 | 2016 |
| CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells SJ Liu, MA Horlbeck, SW Cho, HS Birk, M Malatesta, D He, FJ Attenello, ... Science 355 (6320), eaah7111, 2017 | 731 | 2017 |
| Genomic hallmarks and structural variation in metastatic prostate cancer DA Quigley, HX Dang, SG Zhao, P Lloyd, R Aggarwal, JJ Alumkal, A Foye, ... Cell 174 (3), 758-769. e9, 2018 | 654 | 2018 |
| CRISPR interference efficiently induces specific and reversible gene silencing in human iPSCs MA Mandegar, N Huebsch, EB Frolov, E Shin, A Truong, MP Olvera, ... Cell stem cell 18 (4), 541-553, 2016 | 534 | 2016 |
| DNA damage-mediated induction of a chemoresistant niche LA Gilbert, MT Hemann Cell 143 (3), 355-366, 2010 | 498 | 2010 |
| Nucleosomes impede Cas9 access to DNA in vivo and in vitro MA Horlbeck, LB Witkowsky, B Guglielmi, JM Replogle, LA Gilbert, ... elife 5, e12677, 2016 | 429 | 2016 |
| Versatile protein tagging in cells with split fluorescent protein D Kamiyama, S Sekine, B Barsi-Rhyne, J Hu, B Chen, LA Gilbert, ... Nature communications 7 (1), 11046, 2016 | 426 | 2016 |
| Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing JK Nuñez, J Chen, GC Pommier, JZ Cogan, JM Replogle, C Adriaens, ... Cell 184 (9), 2503-2519. e17, 2021 | 401 | 2021 |
| Mapping the genetic landscape of human cells MA Horlbeck, A Xu, M Wang, NK Bennett, CY Park, D Bogdanoff, ... Cell 174 (4), 953-967. e22, 2018 | 261 | 2018 |
| The DNA methylation landscape of advanced prostate cancer SG Zhao, WS Chen, H Li, A Foye, M Zhang, M Sjöström, R Aggarwal, ... Nature genetics 52 (8), 778-789, 2020 | 242 | 2020 |
| Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent M Jost, Y Chen, LA Gilbert, MA Horlbeck, L Krenning, G Menchon, A Rai, ... Molecular cell 68 (1), 210-223. e6, 2017 | 226 | 2017 |
| Toxoplasma gondii Targets a Protein Phosphatase 2C to the Nuclei of Infected Host Cells LA Gilbert, S Ravindran, JM Turetzky, JC Boothroyd, PJ Bradley Eukaryotic cell 6 (1), 73-83, 2007 | 213 | 2007 |
Jonathan S. WeissmanUCSF/HHMI在 ucsf.edu 的电子邮件经过验证
