Cyclin D as a therapeutic target in cancer EA Musgrove, CE Caldon, J Barraclough, A Stone, RL Sutherland Nature Reviews Cancer 11 (8), 558-572, 2011 | 1553 | 2011 |
Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events RA McCloy, S Rogers, CE Caldon, T Lorca, A Castro, A Burgess Cell cycle 13 (9), 1400-1412, 2014 | 970 | 2014 |
Cell cycle control in breast cancer cells CE Caldon, RJ Daly, RL Sutherland, EA Musgrove Journal of cellular biochemistry 97 (2), 261-274, 2006 | 329 | 2006 |
Cyclin-dependent kinase 2 inhibitors in cancer therapy: an update S Tadesse, EC Caldon, W Tilley, S Wang Journal of medicinal chemistry 62 (9), 4233-4251, 2018 | 210 | 2018 |
Evolution of a molecular switch: universal bacterial GTPases regulate ribosome function CE Caldon, P Yoong, PE March Molecular microbiology 41 (2), 289-297, 2001 | 208 | 2001 |
Targeting CDK2 in cancer: challenges and opportunities for therapy S Tadesse, AT Anshabo, N Portman, E Lim, W Tilley, CE Caldon, S Wang Drug discovery today 25 (2), 406-413, 2020 | 200 | 2020 |
Estrogen signaling and the DNA damage response in hormone dependent breast cancers CE Caldon Frontiers in Oncology, 137, 2014 | 187 | 2014 |
The androgen receptor is a tumor suppressor in estrogen receptor–positive breast cancer TE Hickey, LA Selth, KM Chia, G Laven-Law, HH Milioli, D Roden, ... Nature medicine 27 (2), 310-320, 2021 | 173 | 2021 |
Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancer CE Caldon, EA Musgrove Cell division 5, 1-13, 2010 | 159 | 2010 |
Cyclin E2 overexpression is associated with endocrine resistance but not insensitivity to CDK2 inhibition in human breast cancer cells CE Caldon, CM Sergio, J Kang, A Muthukaruppan, MN Boersma, A Stone, ... Molecular cancer therapeutics 11 (7), 1488-1499, 2012 | 149 | 2012 |
Function of the universally conserved bacterial GTPases CE Caldon, PE March Current opinion in microbiology 6 (2), 135-139, 2003 | 146 | 2003 |
Increased proliferation and altered growth factor dependence of human mammary epithelial cells overexpressing the Gab2 docking protein T Brummer, D Schramek, VM Hayes, HL Bennett, CE Caldon, ... Journal of Biological Chemistry 281 (1), 626-637, 2006 | 143 | 2006 |
Overcoming CDK4/6 inhibitor resistance in ER-positive breast cancer N Portman, S Alexandrou, E Carson, S Wang, E Lim, CE Caldon Endocrine-related cancer 26 (1), R15-R30, 2019 | 139 | 2019 |
Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer J Achinger-Kawecka, F Valdes-Mora, PL Luu, KA Giles, CE Caldon, W Qu, ... Nature communications 11 (1), 320, 2020 | 127 | 2020 |
Identification of functional networks of estrogen-and c-Myc-responsive genes and their relationship to response to tamoxifen therapy in breast cancer EA Musgrove, CM Sergio, S Loi, CK Inman, LR Anderson, MC Alles, ... PloS one 3 (8), e2987, 2008 | 119 | 2008 |
Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer Q Du, SA Bert, NJ Armstrong, CE Caldon, JZ Song, SS Nair, CM Gould, ... Nature communications 10 (1), 416, 2019 | 111 | 2019 |
Regulation of cyclin expression and cell cycle progression in breast epithelial cells by the helix–loop–helix protein Id1 A Swarbrick, MC Åkerfeldt, CSL Lee, CM Sergio, CE Caldon, LJK Hunter, ... Oncogene 24 (3), 381-389, 2005 | 108 | 2005 |
ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer M Kalyuga, D Gallego-Ortega, HJ Lee, DL Roden, MJ Cowley, CE Caldon, ... PLoS biology 10 (12), e1001461, 2012 | 103 | 2012 |
Cell cycle proteins in epithelial cell differentiation: implications for breast cancer CE Caldon, RL Sutherland, EA Musgrove Cell cycle 9 (10), 1918-1928, 2010 | 97 | 2010 |
Functional interaction of 13 yeast SCF complexes with a set of yeast E2 enzymes in vitro BM Kus, CE Caldon, R Andorn‐Broza, AM Edwards Proteins: Structure, Function, and Bioinformatics 54 (3), 455-467, 2003 | 95 | 2003 |