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| Prognostic relevance of integrated genetic profiling in acute myeloid leukemia JP Patel, M Gönen, ME Figueroa, H Fernandez, Z Sun, J Racevskis, ... New England Journal of Medicine 366 (12), 1079-1089, 2012 | 2336 | 2012 |
| Mutations in GNA11 in uveal melanoma CD Van Raamsdonk, KG Griewank, MB Crosby, MC Garrido, S Vemula, ... New England Journal of Medicine 363 (23), 2191-2199, 2010 | 1620 | 2010 |
| Genetic characterization of TET1, TET2, and TET3 alterations in myeloid malignancies O Abdel-Wahab, A Mullally, C Hedvat, G Garcia-Manero, J Patel, ... Blood 114 (1), 144-147, 2009 | 843 | 2009 |
| The bone marrow microenvironment at single-cell resolution AN Tikhonova, I Dolgalev, H Hu, KK Sivaraj, E Hoxha, ... Nature 569 (7755), 222-228, 2019 | 752 | 2019 |
| Restoration of TET2 function blocks aberrant self-renewal and leukemia progression L Cimmino, I Dolgalev, Y Wang, A Yoshimi, GH Martin, J Wang, V Ng, ... Cell 170 (6), 1079-1095. e20, 2017 | 647 | 2017 |
| The integrated landscape of driver genomic alterations in glioblastoma V Frattini, V Trifonov, JM Chan, A Castano, M Lia, F Abate, ST Keir, AX Ji, ... Nature genetics 45 (10), 1141-1149, 2013 | 599 | 2013 |
| Keap1 loss promotes Kras-driven lung cancer and results in dependence on glutaminolysis R Romero, VI Sayin, SM Davidson, MR Bauer, SX Singh, SE LeBoeuf, ... Nature medicine 23 (11), 1362, 2017 | 550 | 2017 |
| The mutational landscape of adenoid cystic carcinoma AS Ho, K Kannan, DM Roy, LGT Morris, I Ganly, N Katabi, D Ramaswami, ... Nature genetics 45 (7), 791-798, 2013 | 470 | 2013 |
| Diverse and targetable kinase alterations drive histiocytic neoplasms EL Diamond, BH Durham, J Haroche, Z Yao, J Ma, SA Parikh, Z Wang, ... Cancer discovery 6 (2), 154-165, 2016 | 465 | 2016 |
| Whole-exome sequencing reveals frequent genetic alterations in BAP1, NF2, CDKN2A, and CUL1 in malignant pleural mesothelioma G Guo, J Chmielecki, C Goparaju, A Heguy, I Dolgalev, M Carbone, ... Cancer research 75 (2), 264-269, 2015 | 356 | 2015 |
| Concurrent loss of the PTEN and RB1 tumor suppressors attenuates RAF dependence in melanomas harboring V600EBRAF F Xing, Y Persaud, CA Pratilas, BS Taylor, M Janakiraman, QB She, ... Oncogene 31 (4), 446-457, 2012 | 237 | 2012 |
| Control of embryonic stem cell identity by BRD4-dependent transcriptional elongation of super-enhancer-associated pluripotency genes R Di Micco, B Fontanals-Cirera, V Low, P Ntziachristos, SK Yuen, ... Cell reports 9 (1), 234-247, 2014 | 232 | 2014 |
| Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis X Cui, RTT Morales, W Qian, H Wang, JP Gagner, I Dolgalev, ... Biomaterials 161, 164-178, 2018 | 224 | 2018 |
| Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma S Zhang, I Dolgalev, T Zhang, H Ran, DA Levine, BG Neel Nature communications 10 (1), 1-16, 2019 | 215 | 2019 |
| Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm M Cerrone, J Montnach, X Lin, YT Zhao, M Zhang, E Agullo-Pascual, ... Nature communications 8 (1), 106, 2017 | 196 | 2017 |
| SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling C Fedele, S Li, KW Teng, CJR Foster, D Peng, H Ran, P Mita, MJ Geer, ... Journal of Experimental Medicine 218 (1), 2021 | 174 | 2021 |
| SPOP mutations in prostate cancer across demographically diverse patient cohorts M Blattner, DJ Lee, C O'Reilly, K Park, TY MacDonald, F Khani, KR Turner, ... Neoplasia 16 (1), 14-W10, 2014 | 174 | 2014 |
| TGF-β-induced quiescence mediates chemoresistance of tumor-propagating cells in squamous cell carcinoma JA Brown, Y Yonekubo, N Hanson, A Sastre-Perona, A Basin, ... Cell stem cell 21 (5), 650-664. e8, 2017 | 150 | 2017 |
| Extensive remodeling of the immune microenvironment in B cell acute lymphoblastic leukemia MT Witkowski, I Dolgalev, NA Evensen, C Ma, T Chambers, KG Roberts, ... Cancer Cell 37 (6), 867-882. e12, 2020 | 135 | 2020 |
