PRC2 is high maintenance JR Yu, CH Lee, O Oksuz, JM Stafford, D Reinberg Genes & development 33 (15-16), 903-935, 2019 | 232 | 2019 |
Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma JM Stafford, CH Lee, P Voigt, N Descostes, R Saldaña-Meyer, JR Yu, ... Science advances 4 (10), eaau5935, 2018 | 152 | 2018 |
Allosteric activation dictates PRC2 activity independent of its recruitment to chromatin CH Lee, JR Yu, S Kumar, Y Jin, G LeRoy, N Bhanu, S Kaneko, BA Garcia, ... Molecular cell 70 (3), 422-434. e6, 2018 | 131 | 2018 |
Distinct stimulatory mechanisms regulate the catalytic activity of polycomb repressive complex 2 CH Lee, M Holder, D Grau, R Saldaña-Meyer, JR Yu, RA Ganai, J Zhang, ... Molecular cell 70 (3), 435-448. e5, 2018 | 124 | 2018 |
Automethylation of PRC2 promotes H3K27 methylation and is impaired in H3K27M pediatric glioma CH Lee, JR Yu, J Granat, R Saldaña-Meyer, J Andrade, G LeRoy, Y Jin, ... Genes & development 33 (19-20), 1428-1440, 2019 | 98 | 2019 |
TGF-β/Smad signaling through DOCK4 facilitates lung adenocarcinoma metastasis JR Yu, Y Tai, Y Jin, MC Hammell, JE Wilkinson, JS Roe, CR Vakoc, ... Genes & development 29 (3), 250-261, 2015 | 80 | 2015 |
Axo-axonic innervation of neocortical pyramidal neurons by GABAergic chandelier cells requires AnkyrinG-associated L1CAM Y Tai, NB Gallo, M Wang, JR Yu, L Van Aelst Neuron 102 (2), 358-372. e9, 2019 | 74 | 2019 |
LEDGF and HDGF2 relieve the nucleosome-induced barrier to transcription in differentiated cells G LeRoy, O Oksuz, N Descostes, Y Aoi, RA Ganai, HO Kara, JR Yu, ... Science Advances 5 (10), eaay3068, 2019 | 69 | 2019 |
The H3K36me2 writer-reader dependency in H3K27M-DIPG JR Yu, G LeRoy, D Bready, JD Frenster, R Saldaña-Meyer, Y Jin, ... Science Advances 7 (29), 2021 | 29 | 2021 |
Dual role for DOCK7 in tangential migration of interneuron precursors in the postnatal forebrain S Nakamuta, YT Yang, CL Wang, NB Gallo, JR Yu, Y Tai, L Van Aelst The Journal of Cell Biology 216 (12), 4313, 2017 | 20 | 2017 |
Inheritance of Repressed Chromatin Domains during S-phase Requires the Histone Chaperone NPM1 T Escobar, JR Yu, S Liu, K Lucero, N Vasilyev, E Nudler, D Reinberg Science Advances, 2022 | 16 | 2022 |