EZH2 Regulates Pancreatic Cancer Subtype Identity and Tumor Progression via Transcriptional Repression of GATA6 S Patil, B Steuber, W Kopp, V Kari, L Urbach, X Wang, S Küffer, ... Cancer research 80 (21), 4620-4632, 2020 | 69 | 2020 |
Cytosolic 5′-nucleotidase 1A is overexpressed in pancreatic cancer and mediates gemcitabine resistance by reducing intracellular gemcitabine metabolites MS Patzak, V Kari, S Patil, FH Hamdan, RG Goetze, M Brunner, ... EBioMedicine 40, 394-405, 2019 | 32 | 2019 |
Utilizing high resolution ultrasound to monitor tumor onset and growth in genetically engineered pancreatic cancer models RG Goetze, SM Buchholz, S Patil, G Petzold, V Ellenrieder, E Hessmann, ... JoVE (Journal of Visualized Experiments), e56979, 2018 | 22 | 2018 |
Mutant and wild-type tumor suppressor p53 induces p300 autoacetylation S Kaypee, SA Sahadevan, S Patil, P Ghosh, NS Roy, S Roy, TK Kundu Iscience 4, 260-272, 2018 | 15 | 2018 |
Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation AMY Zhang, YH Xia, JSH Lin, KH Chu, WCK Wang, TJJ Ruiter, JCC Yang, ... Cell Metabolism 35 (12), 2119-2135. e5, 2023 | 14 | 2023 |
TP53-Status-Dependent Oncogenic EZH2 Activity in Pancreatic Cancer L Versemann, S Patil, B Steuber, Z Zhang, W Kopp, HE Krawczyk, ... Cancers 14 (14), 3451, 2022 | 9 | 2022 |
HSP90 Inhibition Synergizes with Cisplatin to Eliminate Basal-like Pancreatic Ductal Adenocarcinoma Cells KM Ewers, S Patil, W Kopp, J Thomale, T Quilitz, A Magerhans, X Wang, ... Cancers 13 (24), 6163, 2021 | 9 | 2021 |
Oligomers of human histone chaperone NPM1 alter p300/KAT3B folding to induce autoacetylation S Kaypee, SA Sahadevan, D Sudarshan, SH Sinha, S Patil, P Senapati, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1862 (8), 1729-1741, 2018 | 8 | 2018 |
Preclinical evaluation of 1, 2-Diamino-4, 5-dibromobenzene in genetically engineered mouse models of pancreatic cancer RG Goetze, SM Buchholz, N Ou, Q Zhang, S Patil, M Schirmer, SK Singh, ... Cells 8 (6), 563, 2019 | 6 | 2019 |
Cell type of pancreatic ductal adenocarcinoma origin: implications for prognosis and clinical outcomes S Patil, Y Dou, JL Kopp Visceral medicine 38 (1), 4-10, 2022 | 5 | 2022 |
Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer S Patil, T Forster, K Reutlinger, W Kopp, L Versemann, J Spitalieri, ... Cells 10 (12), 3463, 2021 | 5 | 2021 |
NFATc1 is a central mediator of EGFR-induced ARID1A chromatin dissociation during acinar cell reprogramming Z Zhang, X Wang, FH Hamdan, A Likhobabina, S Patil, L Aperdannier, ... Cellular and Molecular Gastroenterology and Hepatology 15 (5), 1219-1246, 2023 | 4 | 2023 |
Acvr1b loss promotes formation of precancerous lesions from acinar and ductal cells of origin K Saeki, S Patil, Y Sun, GH Su, JL Kopp bioRxiv, 2023.06. 08.544226, 2023 | | 2023 |
EZH2-GATA6 axis in Pancreatic ductal adenocarcinoma S Patil Georg-August-Universität Göttingen, 2020 | | 2020 |
Kombinierte Radiochemotherapeutika zur Behandlung von endogenen Pankreaskarzinomen im KPC-Modell–eine feasibility Studie RG Goetze, SM Buchholz, S Patil, M Schirmer, E Hessmann, A Neeße Zeitschrift für Gastroenterologie 57 (09), KV 356, 2019 | | 2019 |
EZH2 controls PDAC plasticity by regulating differentiation genes S Patil, Z Najafova, V Kari, X Wang, H Bohnenberger, W Kopp, J Spitalieri, ... Pancreatology 19, S11, 2019 | | 2019 |
Impact of cytosolic 5'-nucleotidase 1A on chemotherapeutic resistance in pancreatic cancer MS Patzak, E Hessmann, V Kari, J Kitz, S Patil, FM Richards, DI Jodrell, ... Pancreatology 18 (4), S91, 2018 | | 2018 |
The Wild-type and Gain-of-function Mutant p53 Enhance p300 Autoacetylation through Conformational Switching S Kaypee, R Ghosh, SA Sahadevan, S Patil, M Shasmal, P Ghosh, N Roy, ... Cold Spring Harbor Laboratory, 2017 | | 2017 |
Role of oncogenic EZH2 histone methyltransferase activity in PDAC cellular plasticity S Patil, H Witte, A Neesse, S Johnsen, V Ellenrieder, E Hessmann Pancreatology 17 (3), S41, 2017 | | 2017 |