Englerin A, a Selective Inhibitor of Renal Cancer Cell Growth, from Phyllanthus engleri R Ratnayake, D Covell, TT Ransom, KR Gustafson, JA Beutler Organic letters 11 (1), 57-60, 2009 | 288 | 2009 |
Citromycetins and Bilains A–C: New Aromatic Polyketides and Diketopiperazines from Australian Marine-Derived and Terrestrial Penicillium spp. RJ Capon, M Stewart, R Ratnayake, E Lacey, JH Gill Journal of Natural Products 70 (11), 1746-1752, 2007 | 158 | 2007 |
Kibdelones: Novel anticancer polyketides from a rare Australian actinomycete R Ratnayake, E Lacey, S Tennant, JH Gill, RJ Capon Chemistry–A European Journal 13 (5), 1610-1619, 2007 | 101 | 2007 |
C3 and 2D C3 Marfey’s Methods for Amino Acid Analysis in Natural Products S Vijayasarathy, P Prasad, LJ Fremlin, R Ratnayake, AA Salim, Z Khalil, ... Journal of Natural Products 79 (2), 421-427, 2016 | 97 | 2016 |
Englerin A stimulates PKCθ to inhibit insulin signaling and to simultaneously activate HSF1: pharmacologically induced synthetic lethality C Sourbier, BT Scroggins, R Ratnayake, TL Prince, S Lee, MJ Lee, ... Cancer cell 23 (2), 228-237, 2013 | 97 | 2013 |
A tryptoline ring‐distortion strategy leads to complex and diverse biologically active molecules from the indole alkaloid yohimbine NG Paciaroni, R Ratnayake, JH Matthews, VM Norwood IV, AC Arnold, ... Chemistry–A European Journal 23 (18), 4327-4335, 2017 | 77 | 2017 |
Aspergillazines A–E: novel heterocyclic dipeptides from an Australian strain of Aspergillus unilateralis RJ Capon, R Ratnayake, M Stewart, E Lacey, S Tennant, JH Gill Organic & Biomolecular Chemistry 3 (1), 123-129, 2005 | 69 | 2005 |
Grassypeptolides A− C, cytotoxic bis-thiazoline containing marine cyclodepsipeptides JC Kwan, R Ratnayake, KA Abboud, VJ Paul, H Luesch The Journal of organic chemistry 75 (23), 8012-8023, 2010 | 68 | 2010 |
Acremolides A−D, Lipodepsipeptides from an Australian Marine-Derived Fungus, Acremonium sp. R Ratnayake, LJ Fremlin, E Lacey, JH Gill, RJ Capon Journal of natural products 71 (3), 403-408, 2008 | 67 | 2008 |
Gatorbulin-1, a distinct cyclodepsipeptide chemotype, targets a seventh tubulin pharmacological site S Matthew, QY Chen, R Ratnayake, CS Fermaintt, D Lucena-Agell, ... Proceedings of the National Academy of Sciences 118 (9), e2021847118, 2021 | 62 | 2021 |
Isokibdelones: Novel Heterocyclic Polyketides from a Kibdelosporangium sp. R Ratnayake, E Lacey, S Tennant, JH Gill, RJ Capon Organic Letters 8 (23), 5267-5270, 2006 | 61 | 2006 |
Flavonoids from eight tropical plant species that inhibit the multidrug resistance transporter ABCG2 MA Versiani, T Diyabalanage, R Ratnayake, CJ Henrich, SE Bates, ... Journal of natural products 74 (2), 262-266, 2011 | 44 | 2011 |
A tetrapeptide class of biased analgesics from an Australian fungus targets the µ-opioid receptor Z Dekan, S Sianati, A Yousuf, KJ Sutcliffe, A Gillis, C Mallet, P Singh, ... Proceedings of the National Academy of Sciences 116 (44), 22353-22358, 2019 | 42 | 2019 |
Chlorinated englerins with selective inhibition of renal cancer cell growth RK Akee, T Ransom, R Ratnayake, JB McMahon, JA Beutler Journal of natural products 75 (3), 459-463, 2012 | 38 | 2012 |
Caldoramide, a Modified Pentapeptide from the Marine Cyanobacterium Caldora penicillata SP Gunasekera, L Imperial, C Garst, R Ratnayake, LH Dang, VJ Paul, ... Journal of natural products 79 (7), 1867-1871, 2016 | 36 | 2016 |
Development of apratoxin S10 (Apra S10) as an anti-pancreatic cancer agent and its preliminary evaluation in an orthotopic patient-derived xenograft (PDX) model W Cai, R Ratnayake, MH Gerber, QY Chen, Y Yu, H Derendorf, ... Investigational new drugs 37, 364-374, 2019 | 34 | 2019 |
Tasiamide F, a potent inhibitor of cathepsins D and E from a marine cyanobacterium FH Al-Awadhi, R Ratnayake, VJ Paul, H Luesch Bioorganic & medicinal chemistry 24 (15), 3276-3282, 2016 | 34 | 2016 |
Discovery, total synthesis and key structural elements for the immunosuppressive activity of cocosolide, a symmetrical glycosylated macrolide dimer from marine cyanobacteria SP Gunasekera, Y Li, R Ratnayake, D Luo, J Lo, JH Reibenspies, Z Xu, ... Chemistry–A European Journal 22 (24), 8158-8166, 2016 | 34 | 2016 |
Multidimensional screening platform for simultaneously targeting oncogenic KRAS and hypoxia-inducible factors pathways in colorectal cancer MS Bousquet, JJ Ma, R Ratnayake, PA Havre, J Yao, NH Dang, VJ Paul, ... ACS chemical biology 11 (5), 1322-1331, 2016 | 34 | 2016 |
Preventing morphine-seeking behavior through the re-engineering of vincamine’s biological activity VM Norwood IV, AC Brice-Tutt, SO Eans, HM Stacy, G Shi, R Ratnayake, ... Journal of medicinal chemistry 63 (10), 5119-5138, 2020 | 33 | 2020 |