Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate AJ Lopatkin, JM Stokes, EJ Zheng, JH Yang, MK Takahashi, L You, ... Nature microbiology 4 (12), 2109-2117, 2019 | 191 | 2019 |
Benchmarking AlphaFold‐enabled molecular docking predictions for antibiotic discovery F Wong, A Krishnan, EJ Zheng, H Stärk, AL Manson, AM Earl, T Jaakkola, ... Molecular systems biology 18 (9), e11081, 2022 | 125 | 2022 |
Eradicating bacterial persisters with combinations of strongly and weakly metabolism-dependent antibiotics EJ Zheng, JM Stokes, JJ Collins Cell chemical biology 27 (12), 1544-1552. e3, 2020 | 64 | 2020 |
Discovery of a structural class of antibiotics with explainable deep learning F Wong, EJ Zheng, JA Valeri, NM Donghia, MN Anahtar, S Omori, A Li, ... Nature 626 (7997), 177-185, 2024 | 39 | 2024 |
Modulating the evolutionary trajectory of tolerance using antibiotics with different metabolic dependencies EJ Zheng, IW Andrews, AT Grote, AL Manson, MA Alcantar, AM Earl, ... Nature Communications 13 (1), 2525, 2022 | 26 | 2022 |
Discovering small-molecule senolytics with deep neural networks F Wong, S Omori, NM Donghia, EJ Zheng, JJ Collins Nature Aging 3 (6), 734-750, 2023 | 24 | 2023 |
Anahtar F Wong, EJ Zheng, JA Valeri, NM Donghia MN, Omori, S., Li, A., Cubillos-Ruiz, A., Krishnan, A., Jin, W., Manson, AL …, 2023 | 23 | 2023 |
Identification of inhibitors of the E. coli chaperone SurA using in silico and in vitro techniques EW Bell, EJ Zheng, LM Ryno Bioorganic & Medicinal Chemistry Letters 28 (22), 3540-3548, 2018 | 10 | 2018 |
Discovery of antibiotics that selectively kill metabolically dormant bacteria EJ Zheng, JA Valeri, IW Andrews, A Krishnan, P Bandyopadhyay, ... Cell Chemical Biology 31 (4), 712-728. e9, 2024 | 5 | 2024 |
Melis N Anahtar, Satotaka Omori, Alicia Li, Andres Cubillos-Ruiz, Aarti Krishnan, Wengong Jin, et al F Wong, EJ Zheng, JA Valeri, NM Donghia Discovery of a structural class of antibiotics with explainable deep …, 2023 | 5 | 2023 |
Bacterial metabolic state more accurately predicts antibiotic lethality than growth rate. Nat Microbiol. 2019; 4 (12): 2109–17 AJ Lopatkin, JM Stokes, EJ Zheng, JH Yang, MK Takahashi, L You, ... Epub 2019/08/28. https://doi. org/10.1038/s41564-019-0536-0 PMID: 31451773, 0 | 4 | |
An online research immersion program to increase introductory science student confidence and science identity EJ Zheng, E Oakes, J Roden Biochemistry and Molecular Biology Education 52 (1), 45-57, 2024 | 2 | 2024 |
Harnessing antibiotic metabolic dependence to design therapies for tolerance and persistence with improved efficacy and safety EJ Zheng Harvard University, 2022 | | 2022 |