Discovery and characterization of small molecules that target the GTPase Ral C Yan, D Liu, L Li, MF Wempe, S Guin, M Khanna, J Meier, B Hoffman, ... Nature 515 (7527), 443-447, 2014 | 155 | 2014 |
Targeting glycogen metabolism in bladder cancer CR Lew, S Guin, D Theodorescu Nature Reviews Urology 12 (7), 383-391, 2015 | 103 | 2015 |
Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease S Guin, C Pollard, Y Ru, C Ritterson Lew, JE Duex, G Dancik, C Owens, ... Journal of the National Cancer Institute 106 (5), dju062, 2014 | 72 | 2014 |
The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells HP Yao, YQ Zhou, Q Ma, S Guin, SS Padhye, RW Zhang, MH Wang Molecular cancer 10, 1-12, 2011 | 71 | 2011 |
Sustained expression of the RON receptor tyrosine kinase by pancreatic cancer stem cells as a potential targeting moiety for antibody-directed chemotherapeutics SS Padhye, S Guin, HP Yao, YQ Zhou, R Zhang, MH Wang Molecular pharmaceutics 8 (6), 2310-2319, 2011 | 70 | 2011 |
Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy MH Wang, SS Padhye, S Guin, Q Ma, Y Zhou Acta Pharmacologica Sinica 31 (9), 1181-1188, 2010 | 60 | 2010 |
RON receptor tyrosine kinase as a target for delivery of chemodrugs by antibody directed pathway for cancer cell cytotoxicity S Guin, HP Yao, MH Wang Molecular pharmaceutics 7 (2), 386-397, 2010 | 59 | 2010 |
Contributions of KRAS and RAL in non–small-cell lung cancer growth and progression S Guin, Y Ru, MW Wynes, R Mishra, X Lu, C Owens, AE Barόn, VT Vasu, ... Journal of Thoracic Oncology 8 (12), 1492-1501, 2013 | 56 | 2013 |
Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage … Q Ma, S Guin, SS Padhye, YQ Zhou, RW Zhang, MH Wang Molecular cancer 10, 1-15, 2011 | 56 | 2011 |
Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase Q Ma, K Zhang, S Guin, YQ Zhou, MH Wang Molecular cancer 9, 1-15, 2010 | 42 | 2010 |
The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer S Guin, D Theodorescu Acta Pharmacologica Sinica 36 (3), 291-297, 2015 | 41 | 2015 |
Monoclonal antibody (mAb)-induced down-regulation of RON receptor tyrosine kinase diminishes tumorigenic activities of colon cancer cells Z Li, H Yao, S Guin, SS Padhye, YQ Zhou, MH Wang International journal of oncology 37 (2), 473-482, 2010 | 39 | 2010 |
Loss of glycogen debranching enzyme AGL drives bladder tumor growth via induction of hyaluronic acid synthesis S Guin, Y Ru, N Agarwal, CR Lew, C Owens, GP Comi, D Theodorescu Clinical Cancer Research 22 (5), 1274-1283, 2016 | 32 | 2016 |
CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL) D Oldenburg, Y Ru, B Weinhaus, S Cash, D Theodorescu, S Guin BMC cancer 16, 1-12, 2016 | 30 | 2016 |
Targeting acute hypoxic cancer cells by doxorubicin-immunoliposomes directed by monoclonal antibodies specific to RON receptor tyrosine kinase S Guin, Q Ma, S Padhye, YQ Zhou, HP Yao, MH Wang Cancer chemotherapy and pharmacology 67, 1073-1083, 2011 | 27 | 2011 |
RhoC is an unexpected target of RhoGDI2 in prevention of lung colonization of bladder cancer EM Griner, GM Dancik, JC Costello, C Owens, S Guin, MG Edwards, ... Molecular Cancer Research 13 (3), 483-492, 2015 | 23 | 2015 |
Targeted next-generation sequencing reveals exceptionally high rates of molecular driver mutations in never-smokers with lung adenocarcinoma PC Mack, MI Klein, KL Ayers, X Zhou, S Guin, M Fink, M Rossi, H Ai-Kateb, ... The Oncologist 27 (6), 476-486, 2022 | 21 | 2022 |
Glycogen debranching enzyme (AGL) is a novel regulator of non-small cell lung cancer growth CS Richmond, D Oldenburg, G Dancik, DR Meier, B Weinhaus, ... Oncotarget 9 (24), 16718, 2018 | 14 | 2018 |
Genomic case report of a low grade bladder tumor metastasis to lung MJ Van Every, G Dancik, V Paramesh, GT Gurda, DR Meier, SE Cash, ... BMC urology 18, 1-7, 2018 | 5 | 2018 |
Involvement of glycogen debranching enzyme in bladder cancer B Weinhaus, S Guin Biomedical Reports 6 (6), 595-598, 2017 | 5 | 2017 |