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Sunny Guin, PhD
Sunny Guin, PhD
Sema4 Genomics
在 sema4genomics.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Discovery and characterization of small molecules that target the GTPase Ral
C Yan, D Liu, L Li, MF Wempe, S Guin, M Khanna, J Meier, B Hoffman, ...
Nature 515 (7527), 443-447, 2014
1552014
Targeting glycogen metabolism in bladder cancer
CR Lew, S Guin, D Theodorescu
Nature Reviews Urology 12 (7), 383-391, 2015
1032015
Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease
S Guin, C Pollard, Y Ru, C Ritterson Lew, JE Duex, G Dancik, C Owens, ...
Journal of the National Cancer Institute 106 (5), dju062, 2014
722014
The monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells
HP Yao, YQ Zhou, Q Ma, S Guin, SS Padhye, RW Zhang, MH Wang
Molecular cancer 10, 1-12, 2011
712011
Sustained expression of the RON receptor tyrosine kinase by pancreatic cancer stem cells as a potential targeting moiety for antibody-directed chemotherapeutics
SS Padhye, S Guin, HP Yao, YQ Zhou, R Zhang, MH Wang
Molecular pharmaceutics 8 (6), 2310-2319, 2011
702011
Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy
MH Wang, SS Padhye, S Guin, Q Ma, Y Zhou
Acta Pharmacologica Sinica 31 (9), 1181-1188, 2010
602010
RON receptor tyrosine kinase as a target for delivery of chemodrugs by antibody directed pathway for cancer cell cytotoxicity
S Guin, HP Yao, MH Wang
Molecular pharmaceutics 7 (2), 386-397, 2010
592010
Contributions of KRAS and RAL in non–small-cell lung cancer growth and progression
S Guin, Y Ru, MW Wynes, R Mishra, X Lu, C Owens, AE Barόn, VT Vasu, ...
Journal of Thoracic Oncology 8 (12), 1492-1501, 2013
562013
Ribosomal protein S6 kinase (RSK)-2 as a central effector molecule in RON receptor tyrosine kinase mediated epithelial to mesenchymal transition induced by macrophage …
Q Ma, S Guin, SS Padhye, YQ Zhou, RW Zhang, MH Wang
Molecular cancer 10, 1-15, 2011
562011
Deletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase
Q Ma, K Zhang, S Guin, YQ Zhou, MH Wang
Molecular cancer 9, 1-15, 2010
422010
The RAS-RAL axis in cancer: evidence for mutation-specific selectivity in non-small cell lung cancer
S Guin, D Theodorescu
Acta Pharmacologica Sinica 36 (3), 291-297, 2015
412015
Monoclonal antibody (mAb)-induced down-regulation of RON receptor tyrosine kinase diminishes tumorigenic activities of colon cancer cells
Z Li, H Yao, S Guin, SS Padhye, YQ Zhou, MH Wang
International journal of oncology 37 (2), 473-482, 2010
392010
Loss of glycogen debranching enzyme AGL drives bladder tumor growth via induction of hyaluronic acid synthesis
S Guin, Y Ru, N Agarwal, CR Lew, C Owens, GP Comi, D Theodorescu
Clinical Cancer Research 22 (5), 1274-1283, 2016
322016
CD44 and RHAMM are essential for rapid growth of bladder cancer driven by loss of Glycogen Debranching Enzyme (AGL)
D Oldenburg, Y Ru, B Weinhaus, S Cash, D Theodorescu, S Guin
BMC cancer 16, 1-12, 2016
302016
Targeting acute hypoxic cancer cells by doxorubicin-immunoliposomes directed by monoclonal antibodies specific to RON receptor tyrosine kinase
S Guin, Q Ma, S Padhye, YQ Zhou, HP Yao, MH Wang
Cancer chemotherapy and pharmacology 67, 1073-1083, 2011
272011
RhoC is an unexpected target of RhoGDI2 in prevention of lung colonization of bladder cancer
EM Griner, GM Dancik, JC Costello, C Owens, S Guin, MG Edwards, ...
Molecular Cancer Research 13 (3), 483-492, 2015
232015
Targeted next-generation sequencing reveals exceptionally high rates of molecular driver mutations in never-smokers with lung adenocarcinoma
PC Mack, MI Klein, KL Ayers, X Zhou, S Guin, M Fink, M Rossi, H Ai-Kateb, ...
The Oncologist 27 (6), 476-486, 2022
212022
Glycogen debranching enzyme (AGL) is a novel regulator of non-small cell lung cancer growth
CS Richmond, D Oldenburg, G Dancik, DR Meier, B Weinhaus, ...
Oncotarget 9 (24), 16718, 2018
142018
Genomic case report of a low grade bladder tumor metastasis to lung
MJ Van Every, G Dancik, V Paramesh, GT Gurda, DR Meier, SE Cash, ...
BMC urology 18, 1-7, 2018
52018
Involvement of glycogen debranching enzyme in bladder cancer
B Weinhaus, S Guin
Biomedical Reports 6 (6), 595-598, 2017
52017
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