NG-nitro L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists. IL Buxton, DJ Cheek, D Eckman, DP Westfall, KM Sanders, KD Keef Circulation Research 72 (2), 387-395, 1993 | 595 | 1993 |
Regulation of cardiac and smooth muscle Ca2+ channels (CaV1. 2a, b) by protein kinases KD Keef, JR Hume, J Zhong American Journal of Physiology-Cell Physiology 281 (6), C1743-C1756, 2001 | 325 | 2001 |
Cyclic GMP-dependent protein kinase activates cloned BKCa channels expressed in mammalian cells by direct phosphorylation at serine 1072 M Fukao, HS Mason, FC Britton, JL Kenyon, B Horowitz, KD Keef Journal of Biological Chemistry 274 (16), 10927-10935, 1999 | 309 | 1999 |
Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells. T Ishikawa, JR Hume, KD Keef Circulation research 73 (6), 1128-1137, 1993 | 192 | 1993 |
Enteric inhibitory neural regulation of human colonic circular muscle: role of nitric oxide KD Keef, C Du, SM Ward, B McGregor, KM Sanders Gastroenterology 105 (4), 1009-1016, 1993 | 173 | 1993 |
Control of motility patterns in the human colonic circular muscle layer by pacemaker activity MG Rae, N Fleming, DB McGregor, KM Sanders, KD Keef The Journal of physiology 510 (1), 309-320, 1998 | 160 | 1998 |
The mechanism and spread of pacemaker activity through myenteric interstitial cells of Cajal in human small intestine HT Lee, GW Hennig, NW Fleming, KD Keef, NJ Spencer, SM Ward, ... Gastroenterology 132 (5), 1852-1865, 2007 | 136 | 2007 |
Modulation of Ca2+ Channels by Cyclic Nucleotide Cross Activation of Opposing Protein Kinases in Rabbit Portal Vein V Ruiz-Velasco, J Zhong, JR Hume, KD Keef Circulation Research 82 (5), 557-565, 1998 | 135 | 1998 |
Expression and function of KCNH2 (HERG) in the human jejunum AM Farrelly, S Ro, BP Callaghan, MA Khoyi, N Fleming, B Horowitz, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 284 (6 …, 2003 | 117 | 2003 |
Involvement of cyclic GMP in non-adrenergic, non-cholinergic inhibitory neurotransmission in dog proximal colon. SM Ward, HH Dalziel, ME Bradley, IL Buxton, K Keef, DP Westfall, ... British journal of pharmacology 107 (4), 1075, 1992 | 110 | 1992 |
Regulation of BKCa channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid M Fukao, HS Mason, JL Kenyon, B Horowitz, KD Keef Molecular pharmacology 59 (1), 16-23, 2001 | 104 | 2001 |
Basal activation of ATP-sensitive potassium channels in murine colonic smooth muscle cell SD Koh, KK Bradley, MG Rae, KD Keef, B Horowitz, KM Sanders Biophysical journal 75 (4), 1793-1800, 1998 | 104 | 1998 |
Endothelium‐dependent relaxation and hyperpolarization in guinea‐pig coronary artery: role of epoxyeicosatrienoic acid DM Eckman, N Hopkins, C McBride, KD Keef British journal of pharmacology 124 (1), 181-189, 1998 | 101 | 1998 |
Relationship between nitric oxide and vasoactive intestinal polypeptide in enteric inhibitory neurotransmission KD Keef, CWR Shuttleworth, C Xue, O Bayguinov, NG Publicover, ... Neuropharmacology 33 (11), 1303-1314, 1994 | 84 | 1994 |
Roles of peptides in enteric neuromuscular transmission CWR Shuttleworth, KD Keef Regulatory peptides 56 (2-3), 101-120, 1995 | 81 | 1995 |
Modulation of K+ and Ca2+ channels by histamine H1‐receptor stimulation in rabbit coronary artery cells. T Ishikawa, JR Hume, KD Keef The Journal of Physiology 468 (1), 379-400, 1993 | 81 | 1993 |
Septal interstitial cells of Cajal conduct pacemaker activity to excite muscle bundles in human jejunum HT Lee, GW Hennig, NW Fleming, KD Keef, NJ Spencer, SM Ward, ... Gastroenterology 133 (3), 907-917, 2007 | 74 | 2007 |
Relationship between interstitial cells of Cajal, fibroblast-like cells and inhibitory motor nerves in the internal anal sphincter CA Cobine, GW Hennig, M Kurahashi, KM Sanders, SM Ward, KD Keef Cell and tissue research 344, 17-30, 2011 | 70 | 2011 |
Comparison of the actions of acetylcholine and BRL 38227 in the guinea-pig coronary artery. DM Eckman, JD Frankovich, KD Keef British journal of pharmacology 106 (1), 9, 1992 | 69 | 1992 |
Basal release of nitric oxide induces an oscillatory motor pattern in canine colon. KD Keef, DC Murray, KM Sanders, TK Smith The Journal of Physiology 499 (3), 773-786, 1997 | 67 | 1997 |