Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells M Ono, N Kosaka, N Tominaga, Y Yoshioka, F Takeshita, R Takahashi, ... Science signaling 7 (332), ra63-ra63, 2014 | 701 | 2014 |
Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood–brain barrier N Tominaga, N Kosaka, M Ono, T Katsuda, Y Yoshioka, K Tamura, ... Nature communications 6 (1), 6716, 2015 | 691 | 2015 |
Disruption of circulating extracellular vesicles as a novel therapeutic strategy against cancer metastasis N Nishida-Aoki, N Tominaga, F Takeshita, H Sonoda, Y Yoshioka, ... Molecular Therapy 25 (1), 181-191, 2017 | 202 | 2017 |
Trash or Treasure: extracellular microRNAs and cell-to-cell communication N Kosaka, Y Yoshioka, K Hagiwara, N Tominaga, T Katsuda, T Ochiya Frontiers in genetics 4, 173, 2013 | 184 | 2013 |
RPN2-mediated glycosylation of tetraspanin CD63 regulates breast cancer cell malignancy N Tominaga, K Hagiwara, N Kosaka, K Honma, H Nakagama, T Ochiya Molecular cancer 13, 1-11, 2014 | 121 | 2014 |
A novel platform for cancer therapy using extracellular vesicles N Tominaga, Y Yoshioka, T Ochiya Advanced drug delivery reviews 95, 50-55, 2015 | 112 | 2015 |
Altered biodistribution of deglycosylated extracellular vesicles through enhanced cellular uptake N Nishida-Aoki, N Tominaga, N Kosaka, T Ochiya Journal of extracellular vesicles 9 (1), 1713527, 2020 | 69 | 2020 |
Dark side of the exosome: the role of the exosome in cancer metastasis and targeting the exosome as a strategy for cancer therapy N Kosaka, Y Yoshioka, N Tominaga, K Hagiwara, T Katsuda, T Ochiya Future Oncology 10 (4), 671-681, 2014 | 66 | 2014 |
Development of 95-gene classifier as a powerful predictor of recurrences in node-negative and ER-positive breast cancer patients Y Naoi, K Kishi, T Tanei, R Tsunashima, N Tominaga, Y Baba, SJ Kim, ... Breast cancer research and treatment 128, 633-641, 2011 | 60 | 2011 |
Clinicopathological analysis of GATA3-positive breast cancers with special reference to response to neoadjuvant chemotherapy N Tominaga, Y Naoi, K Shimazu, T Nakayama, N Maruyama, ... Annals of oncology 23 (12), 3051-3057, 2012 | 55 | 2012 |
Functional analysis of exosomal microRNA in cell–cell communication research N Kosaka, Y Yoshioka, K Hagiwara, N Tominaga, T Ochiya Circulating MicroRNAs: Methods and Protocols, 1-10, 2013 | 45 | 2013 |
Prediction of pathologic complete response to sequential paclitaxel and 5‐fluorouracil/epirubicin/cyclophosphamide therapy using a 70‐gene classifier for breast cancers Y Naoi, K Kishi, T Tanei, R Tsunashima, N Tominaga, Y Baba, SJ Kim, ... Cancer 117 (16), 3682-3690, 2011 | 37 | 2011 |
Ochiya,. Exosomes from bone marrow mesenchymal stem cells contain a microRNA that promotes dormancy in metastatic breast cancer cells M Ono, N Kosaka, N Tominaga, Y Yoshioka, F Takeshita, RU Takahashi, ... Sci Signal 7, 332, 2014 | 30 | 2014 |
Brain metastatic cancer cells release microRNA-181c-containing extracellular vesicles capable of destructing blood-brain barrier. Nat Commun. 2015; 6: 6716 N Tominaga, N Kosaka, M Ono, T Katsuda, Y Yoshioka, K Tamura, ... Trends Cell Biol 20 (4), 187-195, 0 | 28 | |
Micromanaging of tumor metastasis by extracellular vesicles N Tominaga, T Katsuda, T Ochiya Seminars in Cell & Developmental Biology 40, 52-59, 2015 | 20 | 2015 |
High genomic grade index associated with poor prognosis for lymph node‐negative and estrogen receptor‐positive breast cancers and with good response to chemotherapy Y Naoi, K Kishi, T Tanei, R Tsunashima, N Tominaga, Y Baba, SJ Kim, ... Cancer 117 (3), 472-479, 2011 | 19 | 2011 |
4-Phenylbutyrate restores localization and membrane repair to human dysferlin mutations K Tominaga, N Tominaga, EO Williams, L Rufibach, V Schöwel, S Spuler, ... IScience 25 (1), 2022 | 6 | 2022 |
Anti-cancer role and therapeutic potential of extracellular vesicles N Tominaga Cancers 13 (24), 6303, 2021 | 6 | 2021 |
70-Gene classifier for differentiation between paclitaxel-and docetaxel-sensitive breast cancers Y Naoi, T Tanei, K Kishi, R Tsunashima, N Tominaga, Y Baba, ... Cancer letters 314 (2), 206-212, 2012 | 4 | 2012 |
Dantrolene reduces platelet-derived growth factor (PDGF)-induced vascular smooth muscle cell proliferation and neointimal formation following vascular injury in mice C Sakai, M Mikawa, T Yamamoto, T Uchida, Y Nakamura, H Akase, ... Biochemical and Biophysical Research Communications 623, 51-58, 2022 | 2 | 2022 |