Genetic effects on gene expression across human tissues GTEx Consortium Lead analysts: Aguet François 1 Brown Andrew A. 2 3 4 Castel ... Nature 550 (7675), 204-213, 2017 | 3557 | 2017 |
Exploring the phenotypic consequences of tissue specific gene expression variation inferred from GWAS summary statistics AN Barbeira, SP Dickinson, R Bonazzola, J Zheng, HE Wheeler, ... Nature communications 9 (1), 1825, 2018 | 994 | 2018 |
Landscape of X chromosome inactivation across human tissues T Tukiainen, AC Villani, A Yen, MA Rivas, JL Marshall, R Satija, M Aguirre, ... Nature 550 (7675), 244-248, 2017 | 957 | 2017 |
Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 602 | 2017 |
The impact of rare variation on gene expression across tissues X Li, Y Kim, EK Tsang, JR Davis, FN Damani, C Chiang, GT Hess, ... Nature 550 (7675), 239-243, 2017 | 279 | 2017 |
Co-expression networks reveal the tissue-specific regulation of transcription and splicing A Saha, Y Kim, ADH Gewirtz, B Jo, C Gao, IC McDowell, BE Engelhardt, ... Genome research 27 (11), 1843-1858, 2017 | 183 | 2017 |
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer G Xu, S Chhangawala, E Cocco, P Razavi, Y Cai, JE Otto, L Ferrando, ... Nature genetics 52 (2), 198-207, 2020 | 178 | 2020 |
FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer A Arruabarrena-Aristorena, JLV Maag, S Kittane, Y Cai, WR Karthaus, ... Cancer cell 38 (4), 534-550. e9, 2020 | 94 | 2020 |
Genomic and transcriptomic determinants of response to neoadjuvant therapy in rectal cancer WK Chatila, JK Kim, H Walch, MR Marco, CT Chen, F Wu, DM Omer, ... Nature medicine 28 (8), 1646-1655, 2022 | 83 | 2022 |
The evolution of RET inhibitor resistance in RET-driven lung and thyroid cancers EY Rosen, HH Won, Y Zheng, E Cocco, D Selcuklu, Y Gong, ... Nature communications 13 (1), 1450, 2022 | 77 | 2022 |
Identifying cis-mediators for trans-eQTLs across many human tissues using genomic mediation analysis F Yang, J Wang, BL Pierce, LS Chen, F Aguet, KG Ardlie, BB Cummings, ... Genome research 27 (11), 1859-1871, 2017 | 70 | 2017 |
Trypanosoma brucei TIF2 suppresses VSG switching by maintaining subtelomere integrity SE Jehi, F Wu, B Li Cell research 24 (7), 870-885, 2014 | 65 | 2014 |
TRK xDFG mutations trigger a sensitivity switch from type I to II kinase inhibitors E Cocco, JE Lee, S Kannan, AM Schram, HH Won, S Shifman, A Kulick, ... Cancer discovery 11 (1), 126-141, 2021 | 47 | 2021 |
Genomic Alterations in PIK3CA-Mutated Breast Cancer Result in mTORC1 Activation and Limit the Sensitivity to PI3Kα Inhibitors Y Cai, G Xu, F Wu, F Michelini, C Chan, X Qu, P Selenica, E Ladewig, ... Cancer research 81 (9), 2470-2480, 2021 | 29 | 2021 |
Integrated clinical and genomic analysis identifies driver events and molecular evolution of colitis-associated cancers WK Chatila, H Walch, JF Hechtman, SM Moyer, V Sgambati, DM Faleck, ... Nature communications 14 (1), 110, 2023 | 24 | 2023 |
Intraoperative opioids are associated with decreased recurrence rates in colon adenocarcinoma: a retrospective observational cohort study JB Yuval, J Lee, F Wu, HM Thompson, FS Verheij, HV Gupta, T Irie, ... British journal of anaesthesia 129 (2), 172-181, 2022 | 17 | 2022 |
Adoption of organ preservation and surgeon variability for patients with rectal cancer does not correlate with worse survival JK Kim, H Thompson, RM Jimenez-Rodriguez, F Wu, F Sanchez-Vega, ... Annals of surgical oncology, 1-8, 2021 | 3 | 2021 |
NR2F2 mediates cell growth and endocrine resistance in NF1 loss, ER+ breast cancer Y Cai, P Zhao, F Wu, H Shao, P Razavi, G Xu, M Scaltriti, ... Cancer Research 82 (12_Supplement), 1778-1778, 2022 | 1 | 2022 |
Association between CD8+ PD-1+ T cell infiltration levels and improved response to total neoadjuvant therapy in mismatch-repair proficient locally advanced rectal cancer C Lee, CT Chen, N Urganci, F Wu, C Firat, H Williams, E Seffar, ... Cancer Research 84 (6_Supplement), 1172-1172, 2024 | | 2024 |
Characterization of the tumor microbiome in patients with locally advanced rectal cancer treated with neoadjuvant therapy CM Vanderbilt, WK Chatila, DN Khalil, CT Chen, JK Kim, F Wu, N Schultz, ... Cancer Research 82 (12_Supplement), 3058-3058, 2022 | | 2022 |