Immunodesign of experimental sepsis by cecal ligation and puncture D Rittirsch, MS Huber-Lang, MA Flierl, PA Ward Nature protocols 4 (1), 31-36, 2009 | 2088 | 2009 |
Harmful molecular mechanisms in sepsis D Rittirsch, MA Flierl, PA Ward Nature Reviews Immunology 8 (10), 776-787, 2008 | 1573 | 2008 |
Generation of C5a in the absence of C3: a new complement activation pathway M Huber-Lang, JV Sarma, FS Zetoune, D Rittirsch, TA Neff, SR McGuire, ... Nature medicine 12 (6), 682-687, 2006 | 1176 | 2006 |
Molecular intercommunication between the complement and coagulation systems U Amara, MA Flierl, D Rittirsch, A Klos, H Chen, B Acker, UB Brückner, ... The Journal of Immunology 185 (9), 5628-5636, 2010 | 784 | 2010 |
Interaction between the coagulation and complement system U Amara, D Rittirsch, M Flierl, U Bruckner, A Klos, F Gebhard, JD Lambris, ... Current topics in complement II, 68-76, 2008 | 592 | 2008 |
The disconnect between animal models of sepsis and human sepsis D Rittirsch, LM Hoesel, PA Ward Journal of Leucocyte Biology 81 (1), 137-143, 2007 | 560 | 2007 |
Phagocyte-derived catecholamines enhance acute inflammatory injury MA Flierl, D Rittirsch, BA Nadeau, AJ Chen, JV Sarma, FS Zetoune, ... Nature 449 (7163), 721-725, 2007 | 514 | 2007 |
Functional roles for C5a receptors in sepsis D Rittirsch, MA Flierl, BA Nadeau, DE Day, M Huber-Lang, CR Mackay, ... Nature medicine 14 (5), 551-557, 2008 | 481 | 2008 |
Danger signals activating the immune response after trauma S Hirsiger, HP Simmen, CML Werner, GA Wanner, D Rittirsch Mediators of inflammation 2012 (1), 315941, 2012 | 281 | 2012 |
Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation ML Ekaney, GP Otto, M Sossdorf, C Sponholz, M Boehringer, W Loesche, ... Critical care 18, 1-9, 2014 | 230 | 2014 |
Adverse functions of IL‐17A in experimental sepsis MA Flierl, D Rittirsch, H Gao, LM Hoesel, BA Nadeau, DE Day, ... Wiley Periodicals, Inc., 2008 | 230 | 2008 |
Catecholamines—crafty weapons in the inflammatory arsenal of immune/inflammatory cells or opening Pandora’s box? MA Flierl, D Rittirsch, M Huber-Lang, JV Sarma, PA Ward Molecular medicine 14, 195-204, 2008 | 224 | 2008 |
Early complementopathy after multiple injuries in humans AM Burk, M Martin, MA Flierl, D Rittirsch, M Helm, L Lampl, U Bruckner, ... Shock 37 (4), 348-354, 2012 | 196 | 2012 |
Molecular events in the cardiomyopathy of sepsis MA Flierl, D Rittirsch, MS Huber-Lang, JV Sarma, PA Ward Molecular medicine 14, 327-336, 2008 | 195 | 2008 |
Upregulation of phagocyte-derived catecholamines augments the acute inflammatory response MA Flierl, D Rittirsch, BA Nadeau, JV Sarma, DE Day, AB Lentsch, ... PloS one 4 (2), e4414, 2009 | 192 | 2009 |
Acute lung injury induced by lipopolysaccharide is independent of complement activation D Rittirsch, MA Flierl, DE Day, BA Nadeau, SR McGuire, LM Hoesel, ... The Journal of Immunology 180 (11), 7664-7672, 2008 | 171 | 2008 |
C5 deficiency and C5a or C5aR blockade protects against cerebral malaria SN Patel, J Berghout, FE Lovegrove, K Ayi, A Conroy, L Serghides, ... The Journal of experimental medicine 205 (5), 1133-1143, 2008 | 127 | 2008 |
Inhibition of the alternative complement activation pathway in traumatic brain injury by a monoclonal anti-factor B antibody: a randomized placebo-controlled study in mice I Leinhase, M Rozanski, D Harhausen, JM Thurman, OI Schmidt, ... Journal of Neuroinflammation 4, 1-12, 2007 | 126 | 2007 |
Reduced neuronal cell death after experimental brain injury in mice lacking a functional alternative pathway of complement activation I Leinhase, VM Holers, JM Thurman, D Harhausen, OI Schmidt, ... BMC neuroscience 7, 1-12, 2006 | 122 | 2006 |
Changes and regulation of the C5a receptor on neutrophils during septic shock in humans H Unnewehr, D Rittirsch, JV Sarma, F Zetoune, MA Flierl, M Perl, S Denk, ... The Journal of Immunology 190 (8), 4215-4225, 2013 | 121 | 2013 |