Lipopolysaccharide stimulates platelet secretion and potentiates platelet aggregation via TLR4/MyD88 and the cGMP-dependent protein kinase pathway G Zhang, J Han, EJ Welch, DY Richard, TA Voyno-Yasenetskaya, ... The Journal of Immunology 182 (12), 7997-8004, 2009 | 420 | 2009 |
AMPK activation by metformin suppresses abnormal extracellular matrix remodeling in adipose tissue and ameliorates insulin resistance in obesity T Luo, A Nocon, J Fry, A Sherban, X Rui, B Jiang, XJ Xu, J Han, Y Yan, ... Diabetes 65 (8), 2295-2310, 2016 | 188 | 2016 |
Acute and chronic shear stress differently regulate endothelial internalization of nanocarriers targeted to platelet-endothelial cell adhesion molecule-1 J Han, BJ Zern, VV Shuvaev, PF Davies, S Muro, V Muzykantov ACS nano 6 (10), 8824-8836, 2012 | 114 | 2012 |
Redox Regulation via Glutaredoxin-1 and Protein S-Glutathionylation R Matsui, B Ferran, A Oh, D Croteau, D Shao, J Han, DR Pimentel, ... Antioxidants & redox signaling 32 (10), 677-700, 2020 | 97 | 2020 |
PECAM‐targeted delivery of SOD inhibits endothelial inflammatory response VV Shuvaev, J Han, KJ Yu, S Huang, BJ Hawkins, M Madesh, M Nakada, ... The FASEB Journal 25 (1), 348-357, 2011 | 96 | 2011 |
A redox-resistant sirtuin-1 mutant protects against hepatic metabolic and oxidant stress D Shao, JL Fry, J Han, X Hou, DR Pimentel, R Matsui, RA Cohen, ... Journal of Biological Chemistry 289 (11), 7293-7306, 2014 | 76 | 2014 |
Antioxidant protection by PECAM-targeted delivery of a novel NADPH-oxidase inhibitor to the endothelium in vitro and in vivo ED Hood, CF Greineder, C Dodia, J Han, C Mesaros, VV Shuvaev, ... Journal of controlled release 163 (2), 161-169, 2012 | 75 | 2012 |
Glutaredoxin-1 up-regulation induces soluble vascular endothelial growth factor receptor 1, attenuating post-ischemia limb revascularization CE Murdoch, M Shuler, DJF Haeussler, R Kikuchi, P Bearelly, J Han, ... Journal of Biological Chemistry 289 (12), 8633-8644, 2014 | 70 | 2014 |
Caveolin-1 protects against sepsis by modulating inflammatory response, alleviating bacterial burden, and suppressing thymocyte apoptosis H Feng, L Guo, Z Song, H Gao, D Wang, W Fu, J Han, Z Li, B Huang, ... Journal of Biological Chemistry 285 (33), 25154-25160, 2010 | 68 | 2010 |
A critical role for Lyn kinase in strengthening endothelial integrity and barrier function J Han, G Zhang, EJ Welch, Y Liang, J Fu, SM Vogel, CA Lowell, X Du, ... Blood, The Journal of the American Society of Hematology 122 (25), 4140-4149, 2013 | 66 | 2013 |
Catalase and superoxide dismutase conjugated with platelet-endothelial cell adhesion molecule antibody distinctly alleviate abnormal endothelial permeability caused by … J Han, VV Shuvaev, VR Muzykantov Journal of pharmacology and experimental therapeutics 338 (1), 82-91, 2011 | 64 | 2011 |
Flow shear stress differentially regulates endothelial uptake of nanocarriers targeted to distinct epitopes of PECAM-1 J Han, VV Shuvaev, PF Davies, DM Eckmann, S Muro, VR Muzykantov Journal of Controlled Release 210, 39-47, 2015 | 61 | 2015 |
Anti-Inflammatory Effect of Targeted Delivery of SOD to Endothelium: Mechanism, Synergism with NO Donors and Protective Effects In Vitro and In Vivo VV Shuvaev, J Han, S Tliba, E Arguiri, M Christofidou-Solomidou, ... PLoS One 8 (10), e77002, 2013 | 61 | 2013 |
Glutaredoxin-1 deficiency causes fatty liver and dyslipidemia by inhibiting sirtuin-1 D Shao, J Han, X Hou, J Fry, JB Behring, F Seta, MT Long, HK Roy, ... Antioxidants & redox signaling 27 (6), 313-327, 2017 | 54 | 2017 |
Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor CF Greineder, AM Chacko, S Zaytsev, BJ Zern, R Carnemolla, ED Hood, ... PloS one 8 (11), e80110, 2013 | 51 | 2013 |
The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells J Han, RM Weisbrod, D Shao, Y Watanabe, X Yin, MM Bachschmid, ... Redox biology 9, 306-319, 2016 | 49 | 2016 |
Targeted interception of signaling reactive oxygen species in the vascular endothelium J Han, VV Shuvaev, VR Muzykantov Therapeutic delivery 3 (2), 263-276, 2012 | 43 | 2012 |
T‐cadherin modulates endothelial barrier function AV Andreeva, J Han, MA Kutuzov, J Profirovic, VA Tkachuk, ... Journal of cellular physiology 223 (1), 94-102, 2010 | 32 | 2010 |
Zyxin is involved in thrombin signaling via interaction with PAR‐1 receptor J Han, G Liu, J Profirovic, J Niu, T Voyno-Yasenetskaya The FASEB Journal 23 (12), 4193-4206, 2009 | 32 | 2009 |
LIM kinase 1 promotes endothelial barrier disruption and neutrophil infiltration in mouse lungs M Gorovoy, J Han, H Pan, E Welch, R Neamu, Z Jia, D Predescu, S Vogel, ... Circulation research 105 (6), 549-556, 2009 | 29 | 2009 |