TFAP2C-and p63-dependent networks sequentially rearrange chromatin landscapes to drive human epidermal lineage commitment L Li, Y Wang, JL Torkelson, G Shankar, JM Pattison, HH Zhen, F Fang, ... Cell Stem Cell 24 (2), 271-284. e8, 2019 | 81 | 2019 |
Clinical trial in a dish using iPSCs shows lovastatin improves endothelial dysfunction and cellular cross-talk in LMNA cardiomyopathy N Sayed, C Liu, M Ameen, F Himmati, JZ Zhang, S Khanamiri, JR Moonen, ... Science translational medicine 12 (554), eaax9276, 2020 | 69 | 2020 |
AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma CD Yao, D Haensel, S Gaddam, T Patel, SX Atwood, KY Sarin, ... Nature communications 11 (1), 5079, 2020 | 51 | 2020 |
Endogenous retrovirus-derived lncRNA BANCR promotes cardiomyocyte migration in humans and non-human primates KD Wilson, M Ameen, H Guo, OJ Abilez, L Tian, MR Mumbach, S Diecke, ... Developmental cell 54 (6), 694-709. e9, 2020 | 44 | 2020 |
The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age F Fang, W Cao, W Zhu, N Lam, L Li, S Gaddam, Y Wang, C Kim, ... Cell reports 37 (6), 2021 | 22 | 2021 |
c-FOS drives reversible basal to squamous cell carcinoma transition F Kuonen, NY Li, D Haensel, T Patel, S Gaddam, L Yerly, K Rieger, S Aasi, ... Cell reports 37 (1), 2021 | 15 | 2021 |
Gibbin mesodermal regulation patterns epithelial development A Collier, A Liu, J Torkelson, J Pattison, S Gaddam, H Zhen, T Patel, ... Nature 606 (7912), 188-196, 2022 | 14 | 2022 |
Modeling effects of immunosuppressive drugs on human hearts using induced pluripotent stem cell–derived cardiac organoids and single-cell RNA sequencing K Sallam, D Thomas, S Gaddam, N Lopez, A Beck, L Beach, AJ Rogers, ... Circulation 145 (17), 1367-1369, 2022 | 12 | 2022 |
Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche D Haensel, B Daniel, S Gaddam, C Pan, T Fabo, J Bjelajac, AR Jussila, ... Nature communications 14 (1), 2685, 2023 | 9 | 2023 |
A scalable and cGMP-compatible autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa G Neumayer, JL Torkelson, S Li, K McCarthy, HH Zhen, M Vangipuram, ... Nature Communications 15 (1), 5834, 2024 | 7 | 2024 |
LY6D marks pre-existing resistant basosquamous tumor subpopulations D Haensel, S Gaddam, NY Li, F Gonzalez, T Patel, JM Cloutier, KY Sarin, ... Nature Communications 13 (1), 7520, 2022 | 6 | 2022 |
De novo and inherited variants in coding and regulatory regions in genetic cardiomyopathies N Vadgama, M Ameen, L Sundaram, S Gaddam, ... Human Genomics 16 (1), 55, 2022 | 4 | 2022 |
Biomedical data commons (BMDC) prioritizes B-lymphocyte non-coding genetic variants in type 1 diabetes SN Piekos, S Gaddam, P Bhardwaj, P Radhakrishnan, RV Guha, AE Oro PLoS Computational Biology 17 (9), e1009382, 2021 | 4 | 2021 |
GRHL2 and AP2a coordinate early surface ectoderm lineage commitment during development AE Collier, SN Piekos, A Liu, JM Pattison, F Felix, AA Bailetti, E Sedov, ... Iscience 26 (3), 2023 | 3 | 2023 |
Influence of age on functional memory T cell diversity F Fang, W Cao, W Zhu, N Lam, L Li, S Gaddam, Y Wang, C Kim, ... bioRxiv, 2021.05. 29.446296, 2021 | 2 | 2021 |
Lovastatin improves endothelial dysfunction and cellular crosstalk in LMNA-related dilated cardiomyopathy N Sayed, C Liu, M Ameen, F Himmati, JZ Zhang, S Khanamiri, JR Moonen, ... Science translational medicine 12 (554), 2020 | 1 | 2020 |
087 Basal-to-inflammatory transition and tumor resistance via crosstalk with a pro-inflammatory stromal niche N Li, W Zhang, D Haensel, A Jussila, C Pan, S Gaddam, S Plevritis, A Oro Journal of Investigative Dermatology 144 (8), S16, 2024 | | 2024 |
Acquisition of drug resistance in basal cell nevus syndrome tumors through basal to squamous cell carcinoma transition AR Jussila, D Haensel, S Gaddam, AE Oro Journal of Investigative Dermatology 144 (6), 1368-1377. e6, 2024 | | 2024 |
Super-enhancer interactomes from single cells link clustering and transcription DJ Le, A Hafner, S Gaddam, KC Wang, AN Boettiger bioRxiv, 2024 | | 2024 |
Abstract P1124: Immunosuppression Drug Mediated Cardiovascular Effects R Dexheimer, D Thomas, S Gaddam, A Elezaby, IY Chen, K Wang, ... Circulation Research 133 (Suppl_1), AP1124-AP1124, 2023 | | 2023 |