| High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing CD Sago, MP Lokugamage, K Paunovska, DA Vanover, CM Monaco, ... Proceedings of the National Academy of Sciences 115 (42), E9944-E9952, 2018 | 255 | 2018 |
| Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs MP Lokugamage, D Vanover, J Beyersdorf, MZC Hatit, L Rotolo, ... Nature biomedical engineering 5 (9), 1059-1068, 2021 | 228 | 2021 |
| A direct comparison of in vitro and in vivo nucleic acid delivery mediated by hundreds of nanoparticles reveals a weak correlation K Paunovska, CD Sago, CM Monaco, WH Hudson, MG Castro, ... Nano letters 18 (3), 2148-2157, 2018 | 179 | 2018 |
| Treatment of influenza and SARS-CoV-2 infections via mRNA-encoded Cas13a in rodents EL Blanchard, D Vanover, SS Bawage, PM Tiwari, L Rotolo, J Beyersdorf, ... Nature biotechnology 39 (6), 717-726, 2021 | 159 | 2021 |
| Visualization of early events in mRNA vaccine delivery in non-human primates via PET–CT and near-infrared imaging KE Lindsay, SM Bhosle, C Zurla, J Beyersdorf, KA Rogers, D Vanover, ... Nature biomedical engineering 3 (5), 371-380, 2019 | 153 | 2019 |
| Arginine‐rich peptide‐based mRNA nanocomplexes efficiently instigate cytotoxic T cell immunity dependent on the amphipathic organization of the peptide VK Udhayakumar, A De Beuckelaer, J McCaffrey, CM McCrudden, ... Advanced healthcare materials 6 (13), 1601412, 2017 | 151 | 2017 |
| Structural analysis of respiratory syncytial virus reveals the position of M2-1 between the matrix protein and the ribonucleoprotein complex G Kiss, JM Holl, GM Williams, E Alonas, D Vanover, AW Lifland, ... Journal of virology 88 (13), 7602-7617, 2014 | 148 | 2014 |
| Engineered mRNA-expressed antibodies prevent respiratory syncytial virus infection PM Tiwari, D Vanover, KE Lindsay, SS Bawage, JL Kirschman, S Bhosle, ... Nature communications 9 (1), 3999, 2018 | 116 | 2018 |
| Characterizing exogenous mRNA delivery, trafficking, cytoplasmic release and RNA–protein correlations at the level of single cells JL Kirschman, S Bhosle, D Vanover, EL Blanchard, KH Loomis, C Zurla, ... Nucleic acids research 45 (12), e113-e113, 2017 | 73 | 2017 |
| Species-dependent in vivo mRNA delivery and cellular responses to nanoparticles MZC Hatit, MP Lokugamage, CN Dobrowolski, K Paunovska, H Ni, ... Nature nanotechnology 17 (3), 310-318, 2022 | 72 | 2022 |
| Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung L Rotolo, D Vanover, NC Bruno, HE Peck, C Zurla, J Murray, RK Noel, ... Nature materials 22 (3), 369-379, 2023 | 61 | 2023 |
| Aerosol delivery of synthetic mRNA to vaginal mucosa leads to durable expression of broadly neutralizing antibodies against HIV KE Lindsay, D Vanover, M Thoresen, H King, P Xiao, P Badial, M Araínga, ... Molecular Therapy 28 (3), 805-819, 2020 | 41 | 2020 |
| RSV glycoprotein and genomic RNA dynamics reveal filament assembly prior to the plasma membrane D Vanover, DV Smith, EL Blanchard, E Alonas, JL Kirschman, AW Lifland, ... Nature communications 8 (1), 667, 2017 | 40 | 2017 |
| Combining single RNA sensitive probes with subdiffraction-limited and live-cell imaging enables the characterization of virus dynamics in cells E Alonas, AW Lifland, M Gudheti, D Vanover, J Jung, C Zurla, ... ACS nano 8 (1), 302-315, 2014 | 39 | 2014 |
| Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells SF Enam, SR Kader, N Bodkin, JG Lyon, M Calhoun, C Azrak, PM Tiwari, ... Journal of neuroinflammation 17, 1-24, 2020 | 36 | 2020 |
| Unifying in vitro and in vivo IVT mRNA expression discrepancies in skeletal muscle via mechanotransduction SM Bhosle, KH Loomis, JL Kirschman, EL Blanchard, DA Vanover, ... Biomaterials 159, 189-203, 2018 | 26 | 2018 |
| In Vitro Transcribed mRNA Vaccines with Programmable Stimulation of Innate Immunity KH Loomis, KE Lindsay, C Zurla, SM Bhosle, DA Vanover, EL Blanchard, ... Bioconjugate Chemistry 29 (9), 3072-3083, 2018 | 25 | 2018 |
| High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo SG Huayamares, MP Lokugamage, R Rab, AJDS Sanchez, H Kim, ... Journal of Controlled Release 357, 394-403, 2023 | 24 | 2023 |
| Polymerase-tagged respiratory syncytial virus reveals a dynamic rearrangement of the ribonucleocapsid complex during infection EL Blanchard, MR Braun, AW Lifland, B Ludeke, SL Noton, D Vanover, ... PLoS pathogens 16 (10), e1008987, 2020 | 20 | 2020 |
| Proximity ligation assays for in situ detection of innate immune activation: focus on in vitro-transcribed mRNA EL Blanchard, KH Loomis, SM Bhosle, D Vanover, P Baumhof, B Pitard, ... Molecular Therapy-Nucleic Acids 14, 52-66, 2019 | 15 | 2019 |
