CAR-T cells secreting BiTEs circumvent antigen escape without detectable toxicity BD Choi, X Yu, AP Castano, AA Bouffard, A Schmidts, RC Larson, ... Nature biotechnology 37 (9), 1049-1058, 2019 | 430 | 2019 |
CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma BD Choi, X Yu, AP Castano, H Darr, DB Henderson, AA Bouffard, ... Journal for immunotherapy of cancer 7, 1-8, 2019 | 255 | 2019 |
Tisagenlecleucel CAR T-cell therapy in secondary CNS lymphoma MJ Frigault, J Dietrich, M Martinez-Lage, M Leick, BD Choi, Z DeFilipp, ... Blood, The Journal of the American Society of Hematology 134 (11), 860-866, 2019 | 225 | 2019 |
CAR T cell killing requires the IFNγR pathway in solid but not liquid tumours RC Larson, MC Kann, SR Bailey, NJ Haradhvala, PM Llopis, AA Bouffard, ... Nature 604 (7906), 563-570, 2022 | 208 | 2022 |
Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma Nature Medicine, 2022 | 106 | 2022 |
Safety and efficacy of tisagenlecleucel in primary CNS lymphoma: a phase 1/2 clinical trial MJ Frigault, J Dietrich, K Gallagher, M Roschewski, JT Jordan, D Forst, ... Blood, The Journal of the American Society of Hematology 139 (15), 2306-2315, 2022 | 84 | 2022 |
Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia MB Leick, H Silva, I Scarfò, R Larson, BD Choi, AA Bouffard, K Gallagher, ... Cancer cell 40 (5), 494-508. e5, 2022 | 70 | 2022 |
Single-center experience using anakinra for steroid-refractory immune effector cell-associated neurotoxicity syndrome (ICANS) M Wehrli, K Gallagher, YB Chen, MB Leick, SL McAfee, AR El-Jawahri, ... Journal for immunotherapy of cancer 10 (1), 2022 | 70 | 2022 |
Blockade or deletion of IFNγ reduces macrophage activation without compromising CAR T-cell function in hematologic malignancies SR Bailey, S Vatsa, RC Larson, AA Bouffard, I Scarfò, MC Kann, ... Blood Cancer Discovery 3 (2), 136-153, 2022 | 67 | 2022 |
Immune effector cell-associated hemophagocytic lymphohistiocytosis-like syndrome MR Hines, TE Knight, KO McNerney, MB Leick, T Jain, S Ahmed, ... Transplantation and Cellular Therapy 29 (7), 438. e1-438. e16, 2023 | 66 | 2023 |
Clonal hematopoiesis in patients receiving chimeric antigen receptor T-cell therapy PG Miller, AS Sperling, EJ Brea, MB Leick, GG Fell, M Jan, SH Gohil, ... Blood advances 5 (15), 2982-2986, 2021 | 62 | 2021 |
Loss of imprinting of IGF2 and the epigenetic progenitor model of cancer MB Leick, CJ Shoff, EC Wang, JL Congress, GI Gallicano American journal of stem cells 1 (1), 59, 2012 | 62 | 2012 |
The future of targeting FLT3 activation in AML MB Leick, MJ Levis Current hematologic malignancy reports 12, 153-167, 2017 | 51 | 2017 |
SARS-CoV-2 T-cell immunity to variants of concern following vaccination KME Gallagher, MB Leick, RC Larson, TR Berger, K Katsis, JY Yam, ... BioRxiv, 2021 | 38 | 2021 |
Clinical perspective: treatment of aggressive B cell lymphomas with FDA-approved CAR-T cell therapies MB Leick, MV Maus, MJ Frigault Molecular Therapy 29 (2), 433-441, 2021 | 25 | 2021 |
Cell-based artificial APC resistant to lentiviral transduction for efficient generation of CAR-T cells from various cell sources A Schmidts, LC Marsh, AA Srivastava, AA Bouffard, AC Boroughs, I Scarfò, ... Journal for immunotherapy of cancer 8 (2), 2020 | 22 | 2020 |
Intraventricular CARv3-TEAM-E T cells in recurrent glioblastoma BD Choi, ER Gerstner, MJ Frigault, MB Leick, CW Mount, L Balaj, ... New England Journal of Medicine 390 (14), 1290-1298, 2024 | 20 | 2024 |
Toxicities associated with immunotherapies for hematologic malignancies MB Leick, MV Maus Best Practice & Research Clinical Haematology 31 (2), 158-165, 2018 | 18 | 2018 |
HIV-associated hematological malignancies M Hentrich, SK Barta Springer, 2016 | 18 | 2016 |
Dose-finding study of hepatic arterial infusion of oxaliplatin-based treatment in patients with advanced solid tumors metastatic to the liver AM Tsimberidou, MB Leick, J Lim, S Fu, J Wheler, SA Piha-Paul, D Hong, ... Cancer chemotherapy and pharmacology 71, 389-397, 2013 | 17 | 2013 |