Endothelial HIF-2α contributes to severe pulmonary hypertension due to endothelial-to-mesenchymal transition H Tang, A Babicheva, KM McDermott, Y Gu, RJ Ayon, S Song, Z Wang, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 314 (2 …, 2018 | 196 | 2018 |
Endothelial dysfunction in pulmonary arterial hypertension: an evolving landscape (2017 Grover Conference Series) B Ranchoux, LD Harvey, RJ Ayon, A Babicheva, S Bonnet, SY Chan, ... Pulmonary circulation 8 (1), 2045893217752912, 2018 | 149 | 2018 |
Increased TMEM16A-encoded calcium-activated chloride channel activity is associated with pulmonary hypertension AS Forrest, TC Joyce, ML Huebner, RJ Ayon, M Wiwchar, J Joyce, ... American Journal of Physiology-Cell Physiology 303 (12), C1229-C1243, 2012 | 146 | 2012 |
PFKFB3-mediated endothelial glycolysis promotes pulmonary hypertension Y Cao, X Zhang, L Wang, Q Yang, Q Ma, J Xu, J Wang, L Kovacs, ... Proceedings of the National Academy of Sciences 116 (27), 13394-13403, 2019 | 145 | 2019 |
SGLT inhibitors attenuate NO-dependent vascular relaxation in the pulmonary artery but not in the coronary artery Y Han, YE Cho, R Ayon, R Guo, KD Youssef, M Pan, A Dai, JXJ Yuan, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 309 (9 …, 2015 | 102 | 2015 |
Chronic hypoxia selectively enhances L- and T-type voltage-dependent Ca2+ channel activity in pulmonary artery by upregulating Cav1.2 and Cav3.2 J Wan, A Yamamura, AM Zimnicka, G Voiriot, KA Smith, H Tang, RJ Ayon, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 305 (2 …, 2013 | 99 | 2013 |
Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension H Tang, A Yamamura, H Yamamura, S Song, DR Fraidenburg, J Chen, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 310 (9 …, 2016 | 85 | 2016 |
Flow shear stress enhances intracellular Ca2+ signaling in pulmonary artery smooth muscle cells from patients with pulmonary arterial hypertension S Song, A Yamamura, H Yamamura, RJ Ayon, KA Smith, H Tang, ... American Journal of Physiology-Cell Physiology 307 (4), C373-C383, 2014 | 76 | 2014 |
Calcium-Sensing Receptor Regulates Cytosolic [Ca2+] and Plays a Major Role in the Development of Pulmonary Hypertension KA Smith, RJ Ayon, H Tang, A Makino, JXJ Yuan Frontiers in Physiology 7, 517, 2016 | 66 | 2016 |
Pathogenic role of mTORC1 and mTORC2 in pulmonary hypertension H Tang, K Wu, J Wang, S Vinjamuri, Y Gu, S Song, Z Wang, Q Zhang, ... JACC: Basic to Translational Science 3 (6), 744-762, 2018 | 55 | 2018 |
STIM2 (Stromal Interaction Molecule 2)–Mediated Increase in Resting Cytosolic Free Ca2+ Concentration Stimulates PASMC Proliferation in Pulmonary Arterial … S Song, SG Carr, KM McDermott, M Rodriguez, A Babicheva, A Balistrieri, ... Hypertension 71 (3), 518-529, 2018 | 54 | 2018 |
Chloroquine is a potent pulmonary vasodilator that attenuates hypoxia‐induced pulmonary hypertension K Wu, Q Zhang, X Wu, W Lu, H Tang, Z Liang, Y Gu, S Song, RJ Ayon, ... British journal of pharmacology 174 (22), 4155-4172, 2017 | 54 | 2017 |
Molecular and Functional Significance of Ca2+-Activated Cl− Channels in Pulmonary Arterial Smooth Muscle N Leblanc, AS Forrest, RJ Ayon, M Wiwchar, JE Angermann, ... Pulmonary circulation 5 (2), 244-268, 2015 | 50 | 2015 |
Divergent changes of p53 in pulmonary arterial endothelial and smooth muscle cells involved in the development of pulmonary hypertension Z Wang, K Yang, Q Zheng, C Zhang, H Tang, A Babicheva, Q Jiang, M Li, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 316 (1 …, 2019 | 49 | 2019 |
Hypoxia selectively upregulates cation channels and increases cytosolic [Ca2+] in pulmonary, but not coronary, arterial smooth muscle cells X He, S Song, RJ Ayon, A Balisterieri, SM Black, A Makino, WG Wier, ... American Journal of Physiology-Cell Physiology 314 (4), C504-C517, 2018 | 40 | 2018 |
Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH S Song, RJ Ayon, A Yamamura, H Yamamura, S Dash, A Babicheva, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 312 (3 …, 2017 | 36 | 2017 |
Endothelial upregulation of mechanosensitive channel Piezo1 in pulmonary hypertension Z Wang, J Chen, A Babicheva, PP Jain, M Rodriguez, RJ Ayon, ... American Journal of Physiology-Cell Physiology 321 (6), C1010-C1027, 2021 | 35 | 2021 |
Phosphorylation alters the pharmacology of Ca2+‐activated Cl‐ channels in rabbit pulmonary arterial smooth muscle cells M Wiwchar, R Ayon, IA Greenwood, N Leblanc British journal of pharmacology 158 (5), 1356-1365, 2009 | 33 | 2009 |
MicroRNA-mediated downregulation of K+ channels in pulmonary arterial hypertension A Babicheva, RJ Ayon, T Zhao, JF Ek Vitorin, NM Pohl, A Yamamura, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 318 (1 …, 2020 | 32 | 2020 |
Notch enhances Ca2+ entry by activating calcium-sensing receptors and inhibiting voltage-gated K+ channels S Song, A Babicheva, T Zhao, RJ Ayon, M Rodriguez, S Rahimi, ... American Journal of Physiology-Cell Physiology, 2020 | 25 | 2020 |