microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial–mesenchymal transition A Parikh, C Lee, P Joseph, S Marchini, A Baccarini, V Kolev, C Romualdi, ... Nature communications 5 (1), 2977, 2014 | 287 | 2014 |
A germline DNA polymorphism enhances alternative splicing of the KLF6 tumor suppressor gene and is associated with increased prostate cancer risk G Narla, A DiFeo, HL Reeves, DJ Schaid, J Hirshfeld, E Hod, A Katz, ... Cancer research 65 (4), 1213-1222, 2005 | 265 | 2005 |
Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth RA Mosig, O Dowling, A DiFeo, MCM Ramirez, IC Parker, E Abe, J Diouri, ... Human molecular genetics 16 (9), 1113-1123, 2007 | 250 | 2007 |
Critical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance AB Nagaraj, P Joseph, O Kovalenko, S Singh, A Armstrong, R Redline, ... Oncotarget 6 (27), 23720, 2015 | 221 | 2015 |
Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread G Narla, A DiFeo, S Yao, A Banno, E Hod, HL Reeves, RF Qiao, ... Cancer Research 65 (13), 5761-5768, 2005 | 201 | 2005 |
Mutations in capillary morphogenesis gene-2 result in the allelic disorders juvenile hyaline fibromatosis and infantile systemic hyalinosis O Dowling, A Difeo, MC Ramirez, T Tukel, G Narla, L Bonafe, H Kayserili, ... The American Journal of Human Genetics 73 (4), 957-966, 2003 | 194 | 2003 |
Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ... The Journal of clinical investigation 127 (6), 2081-2090, 2017 | 186 | 2017 |
Frequent inactivation of the tumor suppressor Kruppel‐like factor 6 (KLF6) in hepatocellular carcinoma S Kremer‐Tal, HL Reeves, G Narla, SN Thung, M Schwartz, A Difeo, ... Hepatology 40 (5), 1047-1052, 2004 | 173 | 2004 |
The role of KLF6 and its splice variants in cancer therapy A DiFeo, JA Martignetti, G Narla Drug Resistance Updates 12 (1-2), 1-7, 2009 | 171 | 2009 |
Positively selected enhancer elements endow osteosarcoma cells with metastatic competence JJ Morrow, I Bayles, APW Funnell, TE Miller, A Saiakhova, MM Lizardo, ... Nature medicine 24 (2), 176-185, 2018 | 146 | 2018 |
KLF6-SV1 overexpression accelerates human and mouse prostate cancer progression and metastasis G Narla, A DiFeo, Y Fernandez, S Dhanasekaran, F Huang, J Sangodkar, ... The Journal of clinical investigation 118 (8), 2711-2721, 2008 | 135 | 2008 |
Roles of KLF6 and KLF6-SV1 in ovarian cancer progression and intraperitoneal dissemination A DiFeo, G Narla, J Hirshfeld, O Camacho-Vanegas, J Narla, SL Rose, ... Clinical Cancer Research 12 (12), 3730-3739, 2006 | 135 | 2006 |
Ribosome‐inactivating proteins isolated from dietary bitter melon induce apoptosis and inhibit histone deacetylase‐1 selectively in premalignant and malignant prostate cancer cells SD Xiong, K Yu, XH Liu, LH Yin, A Kirschenbaum, S Yao, G Narla, ... International Journal of Cancer 125 (4), 774-782, 2009 | 120 | 2009 |
Myosin IIA associates with NK cell lytic granules to enable their interaction with F-actin and function at the immunological synapse KB Sanborn, GD Rak, SY Maru, K Demers, A Difeo, JA Martignetti, ... The Journal of Immunology 182 (11), 6969-6984, 2009 | 119 | 2009 |
Loss of matrix metalloproteinase-2 amplifies murine toxin-induced liver fibrosis by upregulating collagen I expression BD Radbill, R Gupta, MCM Ramirez, A DiFeo, JA Martignetti, CE Alvarez, ... Digestive diseases and sciences 56, 406-416, 2011 | 109 | 2011 |
Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation S Kremer-Tal, G Narla, Y Chen, E Hod, A DiFeo, S Yea, JS Lee, ... Journal of hepatology 46 (4), 645-654, 2007 | 98 | 2007 |
Targeting the FOXO1/KLF6 axis regulates EGFR signaling and treatment response J Sangodkar, NS Dhawan, H Melville, VJ Singh, E Yuan, H Rana, ... The Journal of clinical investigation 122 (7), 2637-2651, 2012 | 96 | 2012 |
E-cadherin is a novel transcriptional target of the KLF6 tumor suppressor A DiFeo, G Narla, O Camacho-Vanegas, H Nishio, SL Rose, RE Buller, ... Oncogene 25 (44), 6026-6031, 2006 | 96 | 2006 |
Functional inactivation of the KLF6 tumor suppressor gene by loss of heterozygosity and increased alternative splicing in glioblastoma O Camacho‐Vanegas, G Narla, MS Teixeira, A DiFeo, A Misra, G Singh, ... International journal of cancer 121 (6), 1390-1395, 2007 | 94 | 2007 |
KLF6-SV1 drives breast cancer metastasis and is associated with poor survival R Hatami, AM Sieuwerts, S Izadmehr, Z Yao, RF Qiao, L Papa, MP Look, ... Science translational medicine 5 (169), 169ra12-169ra12, 2013 | 92 | 2013 |