Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms IS Kim, Y Gao, T Welte, H Wang, J Liu, M Janghorban, K Sheng, Y Niu, ... Nature cell biology 21 (9), 1113-1126, 2019 | 266 | 2019 |
Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer M Janghorban, AS Farrell, BL Allen-Petersen, C Pelz, CJ Daniel, J Oddo, ... Proceedings of the National Academy of Sciences 111 (25), 9157-9162, 2014 | 213 | 2014 |
Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis AS Farrell, C Pelz, X Wang, CJ Daniel, Z Wang, Y Su, M Janghorban, ... Molecular and cellular biology, 2013 | 138 | 2013 |
Mechanistic insight into Myc stabilization in breast cancer involving aberrant Axin1 expression X Zhang, AS Farrell, CJ Daniel, H Arnold, C Scanlan, BJ Laraway, ... Proceedings of the National Academy of Sciences 109 (8), 2790-2795, 2012 | 97 | 2012 |
Notch signaling as a regulator of the tumor immune response: to target or not to target? M Janghorban, L Xin, JM Rosen, XHF Zhang Frontiers in immunology 9, 1649, 2018 | 95 | 2018 |
The bone microenvironment increases phenotypic plasticity of ER+ breast cancer cells IL Bado, W Zhang, J Hu, Z Xu, H Wang, P Sarkar, L Li, YW Wan, J Liu, ... Developmental cell 56 (8), 1100-1117. e9, 2021 | 79 | 2021 |
Serine 62-phosphorylated MYC associates with nuclear lamins and its regulation by CIP2A is essential for regenerative proliferation K Myant, X Qiao, T Halonen, C Come, A Laine, M Janghorban, ... Cell reports 12 (6), 1019-1031, 2015 | 73 | 2015 |
Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers CC Farrington, E Yuan, S Mazhar, S Izadmehr, L Hurst, BL Allen-Petersen, ... Journal of Biological Chemistry 295 (3), 757-770, 2020 | 56 | 2020 |
The tumor suppressor phosphatase PP2A-B56α regulates stemness and promotes the initiation of malignancies in a novel murine model M Janghorban, EM Langer, X Wang, D Zachman, CJ Daniel, J Hooper, ... PloS one 12 (11), e0188910, 2017 | 22 | 2017 |
Single-cell analysis unveils the role of the tumor immune microenvironment and notch signaling in dormant minimal residual disease M Janghorban, Y Yang, N Zhao, C Hamor, TM Nguyen, XHF Zhang, ... Cancer research 82 (5), 885-899, 2022 | 19 | 2022 |
Altering MYC phosphorylation in the epidermis increases the stem cell population and contributes to the development, progression, and metastasis of squamous cell carcinoma X Wang, EM Langer, CJ Daniel, M Janghorban, V Wu, XJ Wang, ... Oncogenesis 9 (9), 79, 2020 | 14 | 2020 |
PP2A activation as a strategy for treatment of breast cancer DJ Christensen, J Oddo, AS Farrell, MJ Janghorban, MP Vitek, RC Sears Cancer Research 71 (8_Supplement), 615-615, 2011 | 2 | 2011 |
Phenotypic plasticity of ER+ breast cancer in the bone microenvironment IL Bado, H Wang, J Hu, P Sarkar, J Liu, Z Gugala, Z Xu, W Zhang, W Wu, ... bioRxiv, 2020.11. 14.383000, 2020 | 1 | 2020 |
Pharmacological reactivation of the tumor suppressor protein phosphatase 2A as a novel approach for the treatment of breast cancer CC Farrington, X Wang, M Janghorban, J Liang, A Difeo, R Sears, ... Cancer Research 76 (14_Supplement), 3857-3857, 2016 | 1 | 2016 |
Single-cell RNA sequencing reveals immunosuppressive pathways associated with metastatic breast cancer F Ozmen, TY Ozmen, A Ors, M Janghorban, MJ Rames, X Li, F Behbod, ... medRxiv, 2024.09. 25.24314388, 2024 | | 2024 |
The role of MDSCs in breast cancer dormancy and recurrence. M Janghorban, X Zhang, J Rosen CANCER IMMUNOLOGY RESEARCH 8 (3), 106-107, 2020 | | 2020 |
Abstract B44: The role of MDSCs in breast cancer dormancy and recurrence M Janghorban, X Zhang, J Rosen Cancer Immunology Research 8 (3_Supplement), B44-B44, 2020 | | 2020 |
Post-translational regulation of MYC's oncogenic activity R Sears, A Farrell, X Wang, J Liang, M Janghorban, Y Su, ... MOLECULAR CANCER RESEARCH 13, 2015 | | 2015 |
Abstract PR03: Serine 62 phosphorylated MYC associates with nuclear lamins and its regulation by CIP2A is essential for proliferation induction in vivo K Myant, X Qiao, T Halonen, C Come, A Laine, JI Partanen, EL Ogg, ... Molecular Cancer Therapeutics 13 (10_Supplement), PR03-PR03, 2015 | | 2015 |
Abstract IA10: Post-translational regulation of MYC's oncogenic activity R Sears, A Farrell, X Wang, J Liang, M Janghorban, Y Su, ... Molecular Cancer Therapeutics 13 (10_Supplement), IA10-IA10, 2015 | | 2015 |