Biological targets and mechanisms of action of natural products from marine cyanobacteria LA Salvador-Reyes, H Luesch Natural product reports 32 (3), 478-503, 2015 | 164 | 2015 |
Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor Y Liu, LA Salvador, S Byeon, Y Ying, JC Kwan, BK Law, J Hong, ... Journal of Pharmacology and Experimental Therapeutics 335 (2), 351-361, 2010 | 147 | 2010 |
Cytotoxic halogenated macrolides and modified peptides from the apratoxin-producing marine cyanobacterium Lyngbya bouillonii from Guam S Matthew, LA Salvador, PJ Schupp, VJ Paul, H Luesch Journal of natural products 73 (9), 1544-1552, 2010 | 132 | 2010 |
Veraguamides A− G, Cyclic Hexadepsipeptides from a Dolastatin 16-Producing Cyanobacterium Symploca cf. hydnoides from Guam LA Salvador, JS Biggs, VJ Paul, H Luesch Journal of natural products 74 (5), 917-927, 2011 | 86 | 2011 |
Potent elastase inhibitors from cyanobacteria: Structural basis and mechanisms mediating cytoprotective and anti-inflammatory effects in bronchial epithelial cells LA Salvador, K Taori, JS Biggs, J Jakoncic, DA Ostrov, VJ Paul, H Luesch Journal of medicinal chemistry 56 (3), 1276-1290, 2013 | 75 | 2013 |
Caldora penicillata gen. nov., comb. nov.(Cyanobacteria), a pantropical marine species with biomedical relevance N Engene, A Tronholm, LA Salvador‐Reyes, H Luesch, VJ Paul Journal of phycology 51 (4), 670-681, 2015 | 69 | 2015 |
Caylobolide B, a macrolactone from symplostatin 1-producing marine cyanobacteria Phormidium spp. from Florida LA Salvador, VJ Paul, H Luesch Journal of natural products 73 (9), 1606-1609, 2010 | 67 | 2010 |
Cyanobacterial peptides as a prototype for the design of potent β-secretase inhibitors and the development of selective chemical probes for other aspartic proteases Y Liu, W Zhang, L Li, LA Salvador, T Chen, W Chen, KM Felsenstein, ... Journal of medicinal chemistry 55 (23), 10749-10765, 2012 | 56 | 2012 |
Modulation of activity profiles for largazole-based HDAC inhibitors through alteration of prodrug properties LA Salvador, H Park, FH Al-Awadhi, Y Liu, B Kim, SL Zeller, QY Chen, ... ACS medicinal chemistry letters 5 (8), 905-910, 2014 | 45 | 2014 |
Synergistic Cytotoxicity of Renieramycin M and Doxorubicin in MCF-7 Breast Cancer Cells JO Tun, LA Salvador-Reyes, MC Velarde, N Saito, K Suwanborirux, ... Marine Drugs 17, 356, 2019 | 44 | 2019 |
Targeted natural products discovery from marine cyanobacteria using combined phylogenetic and mass spectrometric evaluation LA Salvador-Reyes, N Engene, VJ Paul, H Luesch Journal of natural products 78 (3), 486-492, 2015 | 43 | 2015 |
Discovery and mechanism of natural products as modulators of histone acetylation L A Salvador, H Luesch Current drug targets 13 (8), 1029-1047, 2012 | 41 | 2012 |
Evaluation of class I HDAC isoform selectivity of largazole analogues B Kim, H Park, LA Salvador, PE Serrano, JC Kwan, SL Zeller, QY Chen, ... Bioorganic & medicinal chemistry letters 24 (16), 3728-3731, 2014 | 35 | 2014 |
Kempopeptin C, a Novel Marine-Derived Serine Protease Inhibitor Targeting Invasive Breast Cancer FH Al-Awadhi, LA Salvador, BK Law, VJ Paul, H Luesch Marine drugs 15 (9), 290, 2017 | 34 | 2017 |
Amantelides A and B, polyhydroxylated macrolides with differential broad-spectrum cytotoxicity from a Guamanian marine cyanobacterium LA Salvador-Reyes, J Sneed, VJ Paul, H Luesch Journal of natural products 78 (8), 1957-1962, 2015 | 32 | 2015 |
Mindapyrroles A–C, Pyoluteorin Analogues from a Shipworm-Associated Bacterium NM Lacerna, BW Miller, AL Lim, JO Tun, JMD Robes, MJB Cleofas, Z Lin, ... Journal of natural products 82 (4), 1024-1028, 2019 | 24 | 2019 |
Largazole pharmacokinetics in rats by LC-MS/MS M Yu, LA Salvador, SKB Sy, Y Tang, RSP Singh, QY Chen, Y Liu, J Hong, ... Marine drugs 12 (3), 1623-1640, 2014 | 23 | 2014 |
Paralytic Shellfish Toxin Uptake, Assimilation, Depuration, and Transformation in the Southeast Asian Green-Lipped Mussel (Perna viridis) JK • Andres, AT Yñiguez, JMM Maister, AD Turner, DEB Olano, ... Toxins 11, 268, 2019 | 22 | 2019 |
Apratyramide, a marine-derived peptidic stimulator of VEGF-A and other growth factors with potential application in wound healing W Cai, LA Salvador-Reyes, W Zhang, QY Chen, S Matthew, R Ratnayake, ... ACS chemical biology 13 (1), 91-99, 2018 | 21 | 2018 |
Largazole is a Brain-Penetrant Class I HDAC Inhibitor with Extended Applicability to Glioblastoma and CNS Diseases FH Al-Awadhi, LA Salvador-Reyes, LA Elsadek, R Ratnayake, QY Chen, ... ACS Chemical Neuroscience 11 (13), 1937-1943, 2020 | 20 | 2020 |