| Molecular evolution of a novel hyperactive Sleeping Beauty transposase enables robust stable gene transfer in vertebrates L Mátés, MKL Chuah, E Belay, B Jerchow, N Manoj, A Acosta-Sanchez, ... Nature genetics 41 (6), 753-761, 2009 | 1039 | 2009 |
| Efficacy and safety of adeno‐associated viral vectors based on serotype 8 and 9 vs. lentiviral vectors for hemophilia B gene therapy T VandenDriessche, L Thorrez, A Acosta‐Sanchez, I Petrus, L Wang, ... Journal of Thrombosis and Haemostasis 5 (1), 16-24, 2007 | 250 | 2007 |
| Hepatocyte‐targeted expression by integrase‐defective lentiviral vectors induces antigen‐specific tolerance in mice with low genotoxic risk J Mátrai, A Cantore, CC Bartholomae, A Annoni, W Wang, ... Hepatology 53 (5), 1696-1707, 2011 | 156 | 2011 |
| IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection M Guilliams, K Movahedi, T Bosschaerts, T VandenDriessche, MK Chuah, ... The Journal of Immunology 182 (2), 1107-1118, 2009 | 151 | 2009 |
| Neutrophils fuel effective immune responses through gluconeogenesis and glycogenesis P Sadiku, JA Willson, EM Ryan, D Sammut, P Coelho, ER Watts, ... Cell metabolism 33 (2), 411-423. e4, 2021 | 128 | 2021 |
| Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates MK Chuah, I Petrus, P De Bleser, C Le Guiner, G Gernoux, O Adjali, ... Molecular Therapy 22 (9), 1605-1613, 2014 | 86 | 2014 |
| Novel hyperactive transposons for genetic modification of induced pluripotent and adult stem cells: a nonviral paradigm for coaxed differentiation E Belay, J Mátrai, A Acosta-Sanchez, L Ma, M Quattrocelli, L Mátés, ... Stem Cells 28 (10), 1760-1771, 2010 | 60 | 2010 |
| Prospective Latin American cohort evaluating outcomes of patients with COVID-19 and abnormal liver tests on admission M Mendizabal, F Pinero, E Ridruejo, M Anders, MD Silveyra, A Torre, ... Annals of Hepatology 21, 100298, 2021 | 51 | 2021 |
| Genome-wide computational analysis reveals cardiomyocyte-specific transcriptional cis-regulatory motifs that enable efficient cardiac gene therapy MY Rincon, S Sarcar, D Danso-Abeam, M Keyaerts, J Matrai, ... Molecular Therapy 23 (1), 43-52, 2015 | 42 | 2015 |
| The establishment of public health policies and the burden of non-alcoholic fatty liver disease in the Americas LA Díaz, E Fuentes-López, G Ayares, F Idalsoaga, J Arnold, ... The Lancet Gastroenterology & Hepatology 7 (6), 552-559, 2022 | 32 | 2022 |
| Comparison of different prognostic scores for patients with cirrhosis hospitalized with SARS-CoV-2 infection M Mendizabal, E Ridruejo, F Pinero, M Anders, M Padilla, LG Toro, ... Annals of Hepatology 25, 100350, 2021 | 23 | 2021 |
| MAIMS: a software tool for sensitive metabolic tracer analysis through the deconvolution of 13C mass isotopologue profiles of large composite metabolites D Verdegem, HNB Moseley, W Vermaelen, AA Sanchez, B Ghesquière Metabolomics 13, 1-10, 2017 | 12 | 2017 |
| Class a capsid assembly modulator RG7907 clears HBV-infected hepatocytes through core-dependent hepatocyte death and proliferation DB Kum, H Vanrusselt, AA Sanchez, V Taverniti, ER Verrier, TF Baumert, ... Hepatology 78 (4), 1252-1265, 2023 | 9 | 2023 |
| Novel non-HAP class A HBV capsid assembly modulators have distinct in vitro and in vivo profiles H Vanrusselt, DB Kum, V Taverniti, C Liu, A Acosta Sanchez, N Corthout, ... Journal of Virology 97 (10), e00722-23, 2023 | 3 | 2023 |
| ALG-005398 is a potent non-HAP class I HBV capsid assembly modulator that strongly reduces HBsAg levels in vivo Y Debing, D Buh Kum, AA Sanchez, H Vanrusselt, C Liu, J Deval, ... Hepatology 74, 502A-503A, 2021 | 3 | 2021 |
| Capsid assembly modulator ALG-000111 and its prodrug ALG-000286 display excellent in vitro and in vivo antiviral activity Y Debing, DB Kum, C Liu, J Deval, H Vanrusselt, AA Sanchez, Q Zhang, ... Cell 500, 4, 2021 | 2 | 2021 |
| Non-HAP class I capsid assembly modulators have distinct profiles and a differentiated mechanism of action Y Debing, H Vanrusselt, D Buh Kum, A Acosta Sanchez, V Taverniti, ... AASLD 2022, 2022 | 1 | 2022 |
| Combinations of hepatocyte-specific transcription factor binding sites identified de novo using a novel bioinformatics algorithm yield robust liver-specific expression I Petrus, M Chuah, AA Sanchez, B Yan, P De Bleser, B Hooghe, J Matrai, ... Hum Gene Ther 19 (October), 1077-1078, 2008 | 1 | 2008 |
| TOP-358-YI Non-HAP CAM-A ALG-006746 and ALG-006780 induce rapid HBsAg reductions in AAV-HBV mice and have favorable pharmacokinetic profiles H Vanrusselt, J Verheyen, K Gupta, L Degrauwe, C Liu, AA Sanchez, ... Journal of Hepatology 80, S728, 2024 | | 2024 |
| An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients Y Debing, H Vanrusselt, L Degrauwe, DAS de Oliveira, CK Kariuki, ... Antiviral Research 224, 105835, 2024 | | 2024 |
