Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms Y Sanchez, J Bachant, H Wang, F Hu, D Liu, M Tetzlaff, SJ Elledge Science 286 (5442), 1166-1171, 1999 | 698 | 1999 |
Mrc1 transduces signals of DNA replication stress to activate Rad53 AA Alcasabas, AJ Osborn, J Bachant, F Hu, PJH Werler, K Bousset, ... Nature Cell Biology 3 (11), 958-965, 2001 | 643 | 2001 |
Sortilin-mediated endocytosis determines levels of the frontotemporal dementia protein, progranulin F Hu, T Padukkavidana, CB Vægter, OA Brady, Y Zheng, IR Mackenzie, ... Neuron 68 (4), 654-667, 2010 | 559 | 2010 |
The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway PM Sullivan, X Zhou, AM Robins, DH Paushter, D Kim, MB Smolka, F Hu Acta neuropathologica communications 4 (1), 1-16, 2016 | 324 | 2016 |
Regulation of the Bub2/Bfa1 GAP complex by Cdc5 and cell cycle checkpoints F Hu, Y Wang, D Liu, Y Li, J Qin, SJ Elledge Cell 107 (5), 655-665, 2001 | 323 | 2001 |
Regulation of TDP‐43 aggregation by phosphorylation andp62/SQSTM1 OA Brady, P Meng, Y Zheng, Y Mao, F Hu Journal of neurochemistry 116 (2), 248-259, 2011 | 244 | 2011 |
Asf1 links Rad53 to control of chromatin assembly F Hu, AA Alcasabas, SJ Elledge Genes & development 15 (9), 1061-1066, 2001 | 200 | 2001 |
The frontotemporal lobar degeneration risk factor, TMEM106B, regulates lysosomal morphology and function OA Brady, Y Zheng, K Murphy, M Huang, F Hu Human molecular genetics 22 (4), 685-695, 2013 | 190 | 2013 |
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin X Zhou, L Sun, F Bastos de Oliveira, X Qi, WJ Brown, MB Smolka, Y Sun, ... Journal of Cell Biology 210 (6), 991-1002, 2015 | 189 | 2015 |
The lysosomal function of progranulin, a guardian against neurodegeneration DH Paushter, H Du, T Feng, F Hu Acta neuropathologica, 1-17, 2018 | 185 | 2018 |
The N-terminal domain of Nogo-A inhibits cell adhesion and axonal outgrowth by an integrin-specific mechanism F Hu, SM Strittmatter The Journal of neuroscience 28 (5), 1262-1269, 2008 | 182 | 2008 |
Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells RQ Miao, Y Gao, KD Harrison, J Prendergast, LM Acevedo, J Yu, F Hu, ... Proceedings of the National Academy of Sciences 103 (29), 10997-11002, 2006 | 168 | 2006 |
The Bfa1/Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit Y Wang, F Hu, SJ Elledge Current Biology 10 (21), 1379-1382, 2000 | 129 | 2000 |
C-terminus of progranulin interacts with the beta-propeller region of sortilin to regulate progranulin trafficking Y Zheng, OA Brady, PS Meng, Y Mao, F Hu PLoS One 6 (6), e21023, 2011 | 121 | 2011 |
A PH domain within OCRL bridges clathrin‐mediated membrane trafficking to phosphoinositide metabolism Y Mao, DM Balkin, R Zoncu, KS Erdmann, L Tomasini, F Hu, MM Jin, ... The EMBO Journal 28 (13), 1831-1842, 2009 | 121 | 2009 |
Genetic variants of Nogo-66 receptor with possible association to schizophrenia block myelin inhibition of axon growth S Budel, T Padukkavidana, BP Liu, Z Feng, F Hu, S Johnson, J Lauren, ... The Journal of Neuroscience 28 (49), 13161-13172, 2008 | 120 | 2008 |
Characterization of myelin ligand complexes with neuronal Nogo-66 receptor family members J Laurén, F Hu, J Chin, J Liao, MS Airaksinen, SM Strittmatter Journal of Biological Chemistry 282 (8), 5715-5725, 2007 | 119 | 2007 |
Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations X Zhou, L Sun, O Bracko, JW Choi, Y Jia, AL Nana, OA Brady, ... Nature Communications 8, 15277, 2017 | 109 | 2017 |
Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function A Manford, T Xia, AK Saxena, C Stefan, F Hu, SD Emr, Y Mao The EMBO journal 29 (9), 1489-1498, 2010 | 106 | 2010 |
Nogo-A interacts with the Nogo-66 receptor through multiple sites to create an isoform-selective subnanomolar agonist F Hu, BP Liu, S Budel, J Liao, J Chin, A Fournier, SM Strittmatter The Journal of neuroscience 25 (22), 5298-5304, 2005 | 97 | 2005 |