Palmitoylome profiling reveals S-palmitoylation–dependent antiviral activity of IFITM3 JS Yount, B Moltedo, YY Yang, G Charron, TM Moran, CB López, ... Nature chemical biology 6 (8), 610-614, 2010 | 377 | 2010 |
The tumour suppressor CYLD is a negative regulator of RIG‐I‐mediated antiviral response CS Friedman, MA O'donnell, D Legarda‐Addison, A Ng, WB Cárdenas, ... EMBO reports 9 (9), 930-936, 2008 | 377 | 2008 |
Robust fluorescent detection of protein fatty-acylation with chemical reporters G Charron, MM Zhang, JS Yount, J Wilson, AS Raghavan, E Shamir, ... Journal of the American Chemical Society 131 (13), 4967-4975, 2009 | 347 | 2009 |
S-palmitoylation and ubiquitination differentially regulate interferon-induced transmembrane protein 3 (IFITM3)-mediated resistance to influenza virus JS Yount, RA Karssemeijer, HC Hang Journal of Biological Chemistry 287 (23), 19631-19641, 2012 | 208 | 2012 |
Opposing activities of IFITM proteins in SARS‐CoV‐2 infection G Shi, AD Kenney, E Kudryashova, A Zani, L Zhang, KK Lai, ... The EMBO journal 40 (3), e106501, 2021 | 207 | 2021 |
Mass-tag labeling reveals site-specific and endogenous levels of protein S-fatty acylation A Percher, S Ramakrishnan, E Thinon, X Yuan, JS Yount, HC Hang Proceedings of the National Academy of Sciences 113 (16), 4302-4307, 2016 | 153 | 2016 |
MDA5 participates in the detection of paramyxovirus infection and is essential for the early activation of dendritic cells in response to Sendai Virus defective interfering … JS Yount, L Gitlin, TM Moran, CB López The Journal of Immunology 180 (7), 4910-4918, 2008 | 148 | 2008 |
Human genetic determinants of viral diseases AD Kenney, JA Dowdle, L Bozzacco, TM McMichael, C St. Gelais, ... Annual review of genetics 51, 241-263, 2017 | 140 | 2017 |
Phosphorylation of the antiviral protein interferon-inducible transmembrane protein 3 (IFITM3) dually regulates its endocytosis and ubiquitination NM Chesarino, TM McMichael, JC Hach, JS Yount Journal of Biological Chemistry 289 (17), 11986-11992, 2014 | 139* | 2014 |
A novel role for viral-defective interfering particles in enhancing dendritic cell maturation JS Yount, TA Kraus, CM Horvath, TM Moran, CB López The Journal of Immunology 177 (7), 4503-4513, 2006 | 135 | 2006 |
SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways S Chen, S Bonifati, Z Qin, C St. Gelais, KM Kodigepalli, BS Barrett, ... Proceedings of the National Academy of Sciences 115 (16), E3798-E3807, 2018 | 126 | 2018 |
Unique type I interferon responses determine the functional fate of migratory lung dendritic cells during influenza virus infection B Moltedo, W Li, JS Yount, TM Moran PLoS pathogens 7 (11), e1002345, 2011 | 120 | 2011 |
E3 ubiquitin ligase NEDD4 promotes influenza virus infection by decreasing levels of the antiviral protein IFITM3 NM Chesarino, TM McMichael, JS Yount PLoS pathogens 11 (8), e1005095, 2015 | 114 | 2015 |
Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1 C St. Gelais, S de Silva, JC Hach, TE White, F Diaz-Griffero, JS Yount, ... Journal of virology 88 (10), 5834-5844, 2014 | 113 | 2014 |
IFITM 3 requires an amphipathic helix for antiviral activity NM Chesarino, AA Compton, TM McMichael, AD Kenney, L Zhang, ... EMBO reports 18 (10), 1740-1751, 2017 | 111 | 2017 |
Antibacterial flavonoids from medicinal plants covalently inactivate type III protein secretion substrates LK Tsou, M Lara-Tejero, J RoseFigura, ZJ Zhang, YC Wang, JS Yount, ... Journal of the American Chemical Society 138 (7), 2209-2218, 2016 | 107 | 2016 |
Natural mutations in IFITM3 modulate post‐translational regulation and toggle antiviral specificity AA Compton, N Roy, F Porrot, A Billet, N Casartelli, JS Yount, C Liang, ... EMBO reports 17 (11), 1657-1671, 2016 | 96 | 2016 |
From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections M Chemudupati, AD Kenney, S Bonifati, A Zani, TM McMichael, L Wu, ... Biochimica Et Biophysica Acta (BBA)-Molecular Cell Research 1866 (3), 382-394, 2019 | 95 | 2019 |
Neutralizing antibody against SARS-CoV-2 spike in COVID-19 patients, health care workers, and convalescent plasma donors C Zeng, JP Evans, R Pearson, P Qu, YM Zheng, RT Robinson, ... JCI insight 5 (22), 2020 | 94 | 2020 |
SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity JM Antonucci, C St. Gelais, S De Silva, JS Yount, C Tang, X Ji, C Shepard, ... Nature medicine 22 (10), 1072-1074, 2016 | 94 | 2016 |