| Ligand bias at metabotropic glutamate 1a receptors: molecular determinants that distinguish β-arrestin-mediated from G protein-mediated signaling AC Emery, JO DiRaddo, E Miller, HA Hathaway, S Pshenichkin, ... Molecular pharmacology 82 (2), 291-301, 2012 | 54 | 2012 |
| A real-time method for measuring cAMP production modulated by Gαi/o-coupled metabotropic glutamate receptors JO DiRaddo, EJ Miller, HA Hathaway, E Grajkowska, B Wroblewska, ... Journal of Pharmacology and Experimental Therapeutics 349 (3), 373-382, 2014 | 38 | 2014 |
| Small molecule and peptide-based CXCR4 modulators as therapeutic agents. A patent review for the period from 2010 to 2018 YA Tahirovic, S Pelly, E Jecs, EJ Miller, SK Sharma, DC Liotta, LJ Wilson Expert opinion on therapeutic patents 30 (2), 87-101, 2020 | 34 | 2020 |
| Discovery of Tetrahydroisoquinoline-Containing CXCR4 Antagonists with Improved in vitro ADMET Properties EJ Miller, E Jecs, VM Truax, BM Katzman, YA Tahirovic, RJ Wilson, ... Journal of Medicinal Chemistry, 2018 | 31 | 2018 |
| Design, synthesis, and pharmacological evaluation of second-generation tetrahydroisoquinoline-based CXCR4 antagonists with favorable ADME properties HH Nguyen, MB Kim, RJ Wilson, CJ Butch, KM Kuo, EJ Miller, ... Journal of Medicinal Chemistry 61 (16), 7168-7188, 2018 | 26 | 2018 |
| Discovery of a Fluorinated Enigmol Analog with Enhanced in Vivo Pharmacokinetic and Anti-Tumor Properties EJ Miller, SG Mays, MT Baillie, RB Howard, DG Culver, M Saindane, ... ACS Medicinal Chemistry Letters 7 (5), 537-542, 2016 | 21 | 2016 |
| Synthesis and SAR of 1, 2, 3, 4-tetrahydroisoquinoline-based CXCR4 antagonists RJ Wilson, E Jecs, EJ Miller, HH Nguyen, YA Tahirovic, VM Truax, ... ACS Medicinal Chemistry Letters 9 (1), 17-22, 2018 | 19 | 2018 |
| Chloride is an agonist of group II and III metabotropic glutamate receptors JO DiRaddo, EJ Miller, C Bowman-Dalley, B Wroblewska, M Javidnia, ... Molecular pharmacology 88 (3), 450-459, 2015 | 18 | 2015 |
| The bioactive protein-ligand conformation of GluN2C-selective positive allosteric modulators bound to the NMDA receptor TM Kaiser, SA Kell, H Kusumoto, G Shaulsky, S Bhattacharya, MP Epplin, ... Molecular pharmacology 93 (2), 141-156, 2018 | 17 | 2018 |
| Synthesis of novel tetrahydroisoquinoline CXCR4 antagonists with rigidified side-chains E Jecs, EJ Miller, RJ Wilson, HH Nguyen, YA Tahirovic, BM Katzman, ... ACS medicinal chemistry letters 9 (2), 89-93, 2018 | 16 | 2018 |
| Discovery of N-Alkyl Piperazine Side Chain Based CXCR4 Antagonists with Improved Drug-like Properties YA Tahirovic, VM Truax, RJ Wilson, E Jecs, HH Nguyen, EJ Miller, ... ACS Medicinal Chemistry Letters 9 (5), 446-451, 2018 | 14 | 2018 |
| ω-Functionalized lipid prodrugs of HIV NtRTI tenofovir with enhanced pharmacokinetic properties N Pribut, M D’Erasmo, M Dasari, KE Giesler, S Iskandar, SK Sharma, ... Journal of Medicinal Chemistry 64 (17), 12917-12937, 2021 | 10 | 2021 |
| Amino-heterocycle tetrahydroisoquinoline CXCR4 antagonists with improved ADME profiles via late-stage Buchwald couplings HH Nguyen, YA Tahirovic, VM Truax, RJ Wilson, E Jecs, EJ Miller, ... ACS Medicinal Chemistry Letters 12 (10), 1605-1612, 2021 | 4 | 2021 |
| Synthesis and Evaluation of Novel Tetrahydronaphthyridine CXCR4 Antagonists with Improved Drug-like Profiles E Jecs, YA Tahirovic, RJ Wilson, EJ Miller, M Kim, V Truax, HH Nguyen, ... Journal of Medicinal Chemistry 65 (5), 4058-4084, 2022 | 3 | 2022 |
| Expanding the toolbox of metabolically stable lipid prodrug strategies KS Toti, N Pribut, M D’Erasmo, M Dasari, SK Sharma, PW Bartsch, ... Frontiers in Pharmacology 13, 1083284, 2023 | 2 | 2023 |
| Nucleoside prodrugs and uses related thereto E Miller, N Pribut, M D'erasimo, M Dasari, K Giesler, S Iskandar, DC Liotta US Patent App. 17/637,365, 2022 | 2 | 2022 |
| Sphingosine Analogs, Compositions, and Methods Related Thereto DC Liotta, J Holt, MG Natchus, MT Baillie, EJ Miller, MR Galinski US Patent App. 14/348,452, 2014 | 2 | 2014 |
| Selective Agonists of mGlu3 Receptors: N-Acetylaspatylglutamate (NAAG) and 2-Hydroxymethylglutamate (HMG) B Wroblewska, S Pshenichkin, EJ Miller, J DiRaddo, E Grajkowska, ... CURRENT NEUROPHARMACOLOGY 9, 67-68, 2011 | 2 | 2011 |
| Discovery of 5′-Substituted 5-Fluoro-2′-deoxyuridine Monophosphate Analogs: A Novel Class of Thymidylate Synthase Inhibitors M Dasari, SC Pelly, J Geng, HB Gold, N Pribut, SK Sharma, MP D’Erasmo, ... ACS Pharmacology & Translational Science 6 (5), 702-709, 2023 | 1 | 2023 |
| Orally bioavailable small molecule CXCR4 antagonists with enhanced efficacy in mouse models of genitourinary cancers EJ Miller, CQ Sun, P Gregorova, E Jecs, YA Tahirovic, RJ Wilson, ... Cancer Research 82 (12_Supplement), 2649-2649, 2022 | 1 | 2022 |
