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Juan Manuel Leyva Castillo
Juan Manuel Leyva Castillo
Boston children's Hospital
在 childrens.harvard.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
TSLP produced by keratinocytes promotes allergen sensitization through skin and thereby triggers atopic march in mice
JM Leyva-Castillo, P Hener, H Jiang, M Li
Journal of Investigative Dermatology 133 (1), 154-163, 2013
2122013
IL-33 promotes food anaphylaxis in epicutaneously sensitized mice by targeting mast cells
C Galand, JM Leyva-Castillo, J Yoon, A Han, MS Lee, ANJ McKenzie, ...
Journal of Allergy and Clinical Immunology 138 (5), 1356-1366, 2016
1832016
Skin thymic stromal lymphopoietin initiates Th2 responses through an orchestrated immune cascade
JM Leyva-Castillo, P Hener, P Michea, H Karasuyama, S Chan, ...
Nature communications 4 (1), 2847, 2013
1542013
Mechanical skin injury promotes food anaphylaxis by driving intestinal mast cell expansion
JM Leyva-Castillo, C Galand, C Kam, O Burton, M Gurish, MA Musser, ...
Immunity 50 (5), 1262-1275. e4, 2019
1422019
RORα-expressing T regulatory cells restrain allergic skin inflammation
N Malhotra, JM Leyva-Castillo, U Jadhav, O Barreiro, C Kam, NK O’Neill, ...
Science immunology 3 (21), eaao6923, 2018
942018
Human RELA haploinsufficiency results in autosomal-dominant chronic mucocutaneous ulceration
YR Badran, F Dedeoglu, JM Leyva Castillo, W Bainter, TK Ohsumi, ...
Journal of Experimental Medicine 214 (7), 1937-1947, 2017
752017
IL-23 induced in keratinocytes by endogenous TLR4 ligands polarizes dendritic cells to drive IL-22 responses to skin immunization
J Yoon, JM Leyva-Castillo, G Wang, C Galand, MK Oyoshi, L Kumar, ...
Journal of Experimental Medicine 213 (10), 2147-2166, 2016
752016
A regulatory T cell Notch4–GDF15 axis licenses tissue inflammation in asthma
H Harb, E Stephen-Victor, E Crestani, M Benamar, A Massoud, Y Cui, ...
Nature immunology 21 (11), 1359-1370, 2020
632020
ILC2 activation by keratinocyte-derived IL-25 drives IL-13 production at sites of allergic skin inflammation
JM Leyva-Castillo, C Galand, S Mashiko, R Bissonnette, A McGurk, ...
Journal of Allergy and Clinical Immunology 145 (6), 1606-1614. e4, 2020
592020
IL-22 derived from γδ T cells restricts Staphylococcus aureus infection of mechanically injured skin
N Malhotra, J Yoon, JM Leyva-Castillo, C Galand, N Archer, LS Miller, ...
Journal of Allergy and Clinical Immunology 138 (4), 1098-1107. e3, 2016
542016
IL-22 promotes allergic airway inflammation in epicutaneously sensitized mice
JM Leyva-Castillo, J Yoon, RS Geha
Journal of Allergy and Clinical Immunology 143 (2), 619-630. e7, 2019
402019
Counterregulation between thymic stromal lymphopoietin–and IL-23–driven immune axes shapes skin inflammation in mice with epidermal barrier defects
J Li, JM Leyva-Castillo, P Hener, A Eisenmann, S Zaafouri, N Jonca, ...
Journal of Allergy and Clinical Immunology 138 (1), 150-161. e13, 2016
292016
Mast cell–derived IL-13 downregulates IL-12 production by skin dendritic cells to inhibit the TH1 cell response to cutaneous antigen exposure
JM Leyva-Castillo, M Das, E Artru, J Yoon, C Galand, RS Geha
Journal of Allergy and Clinical Immunology 147 (6), 2305-2315. e3, 2021
272021
Allergic skin inflammation and S. aureus skin colonization are mutually reinforcing
JM Leyva-Castillo, A McGurk, MDR Geha
Clinical Immunology 218, 108511, 2020
162020
Basophil-derived IL-4 promotes cutaneous Staphylococcus aureus infection
JM Leyva-Castillo, M Das, J Kane, M Strakosha, S Singh, DSH Wong, ...
JCI insight 6 (21), 2021
122021
Thymic stromal lymphopoietin and atopic diseases
JM Leyva-Castillo, M Li
Revue Française d'Allergologie 54 (5), 364-376, 2014
122014
Single-cell transcriptome profile of mouse skin undergoing antigen-driven allergic inflammation recapitulates findings in atopic dermatitis skin lesions
JM Leyva-Castillo, L Sun, SY Wu, S Rockowitz, P Sliz, RS Geha
Journal of Allergy and Clinical Immunology 150 (2), 373-384, 2022
82022
Linker-Improved Chimeric Endolysin Selectively Kills Staphylococcus aureus In Vitro, on Reconstituted Human Epidermis, and in a Murine Model of Skin Infection
F Eichenseher, BL Herpers, P Badoux, JM Leyva-Castillo, RS Geha, ...
Antimicrobial Agents and Chemotherapy 66 (5), e02273-21, 2022
52022
The IL-4Rα Q576R polymorphism is associated with increased severity of atopic dermatitis and exaggerates allergic skin inflammation in mice
B Yang, H Wilkie, M Das, M Timilshina, W Bainter, B Woods, M Daya, ...
Journal of Allergy and Clinical Immunology 151 (5), 1296-1306. e7, 2023
32023
Cutaneous type 2 innate lymphoid cells come in distinct flavors
JM Leyva-Castillo, RS Geha
JID Innovations 1 (3), 100059, 2021
32021
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