CPT1A-mediated fat oxidation, mechanisms, and therapeutic potential IR Schlaepfer, M Joshi Endocrinology 161 (2), bqz046, 2020 | 399 | 2020 |
Lipid catabolism via CPT1 as a therapeutic target for prostate cancer IR Schlaepfer, L Rider, LU Rodrigues, MA Gijón, CT Pac, L Romero, ... Molecular cancer therapeutics 13 (10), 2361-2371, 2014 | 296 | 2014 |
The CHRNA5/A3/B4 gene cluster variability as an important determinant of early alcohol and tobacco initiation in young adults IR Schlaepfer, NR Hoft, AC Collins, RP Corley, JK Hewitt, CJ Hopfer, ... Biological psychiatry 63 (11), 1039-1046, 2008 | 205 | 2008 |
Association of the neuronal nicotinic receptor β2 subunit gene (CHRNB2) with subjective responses to alcohol and nicotine MA Ehringer, HV Clegg, AC Collins, RP Corley, T Crowley, JK Hewitt, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 144 …, 2007 | 149 | 2007 |
Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase DR Jensen, IR Schlaepfer, CL Morin, DS Pennington, T Marcell, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 1997 | 149 | 1997 |
The genetic components of alcohol and nicotine co-addiction: from genes to behavior IR Schlaepfer, NR Hoft, MA Ehringer Current drug abuse reviews 1 (2), 124-134, 2008 | 124 | 2008 |
The neuronal nicotinic receptor subunit genes (CHRNA6 and CHRNB3) are associated with subjective responses to tobacco JS Zeiger, BC Haberstick, I Schlaepfer, AC Collins, RP Corley, TJ Crowley, ... Human molecular genetics 17 (5), 724-734, 2008 | 120 | 2008 |
Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample NR Hoft, RP Corley, MB McQueen, IR Schlaepfer, D Huizinga, ... Neuropsychopharmacology 34 (3), 698-706, 2009 | 113 | 2009 |
Aberrant lipid metabolism promotes prostate cancer: role in cell survival under hypoxia and extracellular vesicles biogenesis G Deep, IR Schlaepfer International Journal of Molecular Sciences 17 (7), 1061, 2016 | 105 | 2016 |
Lipid metabolism and endocrine resistance in prostate cancer, and new opportunities for therapy GE Stoykova, IR Schlaepfer International journal of molecular sciences 20 (11), 2626, 2019 | 104 | 2019 |
Hypoxia induces triglycerides accumulation in prostate cancer cells and extracellular vesicles supporting growth and invasiveness following reoxygenation IR Schlaepfer, DK Nambiar, A Ramteke, R Kumar, D Dhar, C Agarwal, ... Oncotarget 6 (26), 22836, 2015 | 103 | 2015 |
Tumor necrosis factor-alpha eliminates binding of NF-Y and an octamer-binding protein to the lipoprotein lipase promoter in 3T3-L1 adipocytes. CL Morin, IR Schlaepfer, RH Eckel The Journal of clinical investigation 95 (4), 1684-1689, 1995 | 93 | 1995 |
Progestin modulates the lipid profile and sensitivity of breast cancer cells to docetaxel IR Schlaepfer, CA Hitz, MA Gijón, BC Bergman, RH Eckel, BM Jacobsen Molecular and cellular endocrinology 363 (1-2), 111-121, 2012 | 82 | 2012 |
Targeting fatty acid oxidation to promote anoikis and inhibit ovarian cancer progression BT Sawyer, L Qamar, TM Yamamoto, A McMellen, ZL Watson, JK Richer, ... Molecular Cancer Research 18 (7), 1088-1098, 2020 | 81 | 2020 |
Lipid catabolism inhibition sensitizes prostate cancer cells to antiandrogen blockade TW Flaig, M Salzmann-Sullivan, LJ Su, Z Zhang, M Joshi, MA Gijón, J Kim, ... Oncotarget 8 (34), 56051, 2017 | 80 | 2017 |
Raman and coherent anti-Stokes Raman scattering microscopy studies of changes in lipid content and composition in hormone-treated breast and prostate cancer cells MC Potcoava, GL Futia, J Aughenbaugh, IR Schlaepfer, EA Gibson Journal of Biomedical Optics 19 (11), 111605-111605, 2014 | 75 | 2014 |
Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[18F]Fluoro-d-Glucose Uptake in Prostate Cancer Mouse Xenografts IR Schlaepfer, LM Glodé, CA Hitz, CT Pac, KE Boyle, P Maroni, G Deep, ... Molecular Imaging and Biology 17, 529-538, 2015 | 69 | 2015 |
ATG14 facilitated lipophagy in cancer cells induce ER stress mediated mitoptosis through a ROS dependent pathway S Mukhopadhyay, IR Schlaepfer, BC Bergman, PK Panda, PP Praharaj, ... Free Radical Biology and Medicine 104, 199-213, 2017 | 63 | 2017 |
Tissue-specific regulation of lipoprotein lipase by isoproterenol in normal-weight humans RH Eckel, DR Jensen, IR Schlaepfer, TJ Yost American Journal of Physiology-Regulatory, Integrative and Comparative …, 1996 | 40 | 1996 |
A novel approach to target hypoxic cancer cells via combining β-oxidation inhibitor etomoxir with radiation A Dheeraj, C Agarwal, IR Schlaepfer, D Raben, R Singh, R Agarwal, ... Hypoxia, 23-33, 2018 | 38 | 2018 |