Identification and characterization of Cardiac Glycosides as senolytic compounds F Triana-Martínez, P Picallos-Rabina, S Da Silva-Álvarez, F Pietrocola, ... Nature communications 10 (1), 4731, 2019 | 317 | 2019 |
Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes E Dominguez, A Galmozzi, JW Chang, KL Hsu, J Pawlak, W Li, C Godio, ... Nature chemical biology 10 (2), 113-121, 2014 | 144 | 2014 |
Role of the inflammation-autophagy-senescence integrative network in osteoarthritis C Vinatier, E Domínguez, J Guicheux, B Caramés Frontiers in physiology 9, 706, 2018 | 137 | 2018 |
Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy U Nogueira-Recalde, I Lorenzo-Gómez, FJ Blanco, MI Loza, D Grassi, ... EBioMedicine 45, 588-605, 2019 | 120 | 2019 |
Synthesis and binding affinity of new pyrazole and isoxazole derivatives as potential atypical antipsychotics M Barcelo, E Ravina, CF Masaguer, E Dominguez, FM Areias, J Brea, ... Bioorganic & medicinal chemistry letters 17 (17), 4873-4877, 2007 | 103 | 2007 |
Beyond tumor suppression: senescence in cancer stemness and tumor dormancy F Triana-Martínez, MI Loza, E Domínguez Cells 9 (2), 346, 2020 | 93 | 2020 |
Absorption of intact protein molecules across the pulmonary air-tissue barrier KG Bensch, E Dominguez, AA Liebow Science 157 (3793), 1204-1206, 1967 | 75 | 1967 |
Lack of adipocyte-fndc5/irisin expression and secretion reduces thermogenesis and enhances adipogenesis D Pérez-Sotelo, A Roca-Rivada, I Baamonde, J Baltar, AI Castro, ... Scientific reports 7 (1), 16289, 2017 | 61 | 2017 |
Extensive linkage disequilibrium mapping at HTR2A and DRD3 for schizophrenia susceptibility genes in the Galician population E Domínguez, MI Loza, F Padín, A Gesteira, E Paz, M Páramo, J Brenlla, ... Schizophrenia research 90 (1-3), 123-129, 2007 | 49 | 2007 |
The tumor suppressor SASH1 interacts with the signal adaptor CRKL to inhibit epithelial–mesenchymal transition and metastasis in colorectal cancer FC Franke, J Müller, M Abal, ED Medina, U Nitsche, H Weidmann, ... Cellular and Molecular Gastroenterology and Hepatology 7 (1), 33-53, 2019 | 46 | 2019 |
Emerging opportunities and concerns for drug discovery at serotonin 5-5-ht2b receptors J Brea, J Castro-Palomino, S Yeste, E Cubero, A Párraga, E Domínguez, ... Current topics in medicinal chemistry 10 (5), 493-503, 2010 | 42 | 2010 |
Synthesis, binding affinity, and molecular docking analysis of new benzofuranone derivatives as potential antipsychotics R Aranda, K Villalba, E Ravina, CF Masaguer, J Brea, F Areias, ... Journal of medicinal chemistry 51 (19), 6085-6094, 2008 | 41 | 2008 |
Synthesis, 3D‐QSAR, and Structural Modeling of Benzolactam Derivatives with Binding Affinity for the D2 and D3 Receptors L López, J Selent, R Ortega, CF Masaguer, E Domínguez, F Areias, ... ChemMedChem 5 (8), 1300-1317, 2010 | 37 | 2010 |
In silico directed chemical probing of the adenosine receptor family FM Areias, J Brea, E Gregori-Puigjané, MEA Zaki, MA Carvalho, ... Bioorganic & medicinal chemistry 18 (9), 3043-3052, 2010 | 37 | 2010 |
Application of activity-based protein profiling to study enzyme function in adipocytes A Galmozzi, E Dominguez, BF Cravatt, E Saez Methods in enzymology 538, 151-169, 2014 | 34 | 2014 |
Parallel regulation by olanzapine of the patterns of expression of 5-HT2A and D3 receptors in rat central nervous system and blood cells JF Padín, MA Rodríguez, E Domínguez, IG Dopeso-Reyes, M Buceta, ... Neuropharmacology 51 (4), 923-932, 2006 | 34 | 2006 |
A comprehensive tyrosine phosphoproteomic analysis reveals novel components of the platelet CLEC-2 signaling cascade I Izquierdo, MN Barrachina, L Hermida-Nogueira, V Casas, LA Morán, ... Thrombosis and Haemostasis 120 (02), 262-276, 2020 | 29 | 2020 |
Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif L Carro, E Raviña, E Domínguez, J Brea, MI Loza, CF Masaguer Bioorganic & medicinal chemistry letters 19 (21), 6059-6062, 2009 | 23 | 2009 |
The human VGF-derived bioactive peptide TLQP-21 binds heat shock 71 kDa protein 8 (HSPA8) on the surface of SH-SY5Y cells S Akhter, S Chakraborty, D Moutinho, E Álvarez-Coiradas, I Rosa, ... PLoS One 12 (9), e0185176, 2017 | 19 | 2017 |
A common haplotype of DRD3 affected by recent positive selection is associated with protection from schizophrenia J Costas, N Carrera, E Domínguez, E Vilella, L Martorell, J Valero, ... Human genetics 124, 607-613, 2009 | 18 | 2009 |