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Marta Sanchez-Martin
Marta Sanchez-Martin
Ikena Oncology
在 ikenaoncology.com 的电子邮件经过验证 - 首页
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Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia
E Piovan, J Yu, V Tosello, D Herranz, A Ambesi-Impiombato, AC Da Silva, ...
Cancer cell 24 (6), 766-776, 2013
2882013
Multivalent small-molecule pan-RAS inhibitors
ME Welsch, A Kaplan, JM Chambers, ME Stokes, PH Bos, A Zask, ...
Cell 168 (5), 878-889. e29, 2017
2672017
CXCL12-producing vascular endothelial niches control acute T cell leukemia maintenance
LA Pitt, AN Tikhonova, H Hu, T Trimarchi, B King, Y Gong, ...
Cancer cell 27 (6), 755-768, 2015
2652015
Translating cancer genomics into precision medicine with artificial intelligence: applications, challenges and future perspectives
J Xu, P Yang, S Xue, B Sharma, M Sanchez-Martin, F Wang, KA Beaty, ...
Human genetics 138 (2), 109-124, 2019
2352019
The NOTCH1-MYC highway toward T-cell acute lymphoblastic leukemia
M Sanchez-Martin, A Ferrando
Blood, The Journal of the American Society of Hematology 129 (9), 1124-1133, 2017
2332017
Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia
Nature Medicine, 2015
2052015
Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia
K Oshima, H Khiabanian, AC da Silva-Almeida, G Tzoneva, F Abate, ...
Proceedings of the National Academy of Sciences 113 (40), 11306-11311, 2016
1972016
RHOA G17V induces T follicular helper cell specification and promotes lymphomagenesis
JR Cortes, A Ambesi-Impiombato, L Couronné, SA Quinn, CS Kim, ...
Cancer cell 33 (2), 259-273. e7, 2018
1902018
Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia
G Tzoneva, CL Dieck, K Oshima, A Ambesi-Impiombato, ...
Nature 553 (7689), 511-514, 2018
1122018
Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias
K Wang, M Sanchez-Martin, X Wang, KM Knapp, R Koche, L Vu, ...
Leukemia 31 (1), 151-158, 2017
802017
Synergistic antileukemic therapies in NOTCH1-induced T-ALL
Sanchez-Martin M, Ambesi-Impiombato A, Q Y, H D, B M, G T, P E, T MS, ...
PNAS, 2017
652017
Differential action of small molecule HER kinase inhibitors on receptor heterodimerization: therapeutic implications
M Sanchez‐Martin, A Pandiella
International journal of cancer 131 (1), 244-252, 2012
492012
Comprehensive characterisation of compartment-specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma
RR Luis Arnes, Zhaoqi Liu, Jiguang Wang,Hans Carlo Maurer, Irina ...
Gut, 2018
48*2018
Therapeutic targeting of HES1 transcriptional programs in T-ALL
SA Schnell, A Ambesi-Impiombato, M Sanchez-Martin, L Belver, L Xu, ...
Blood, The Journal of the American Society of Hematology 125 (18), 2806-2814, 2015
472015
Structure and mechanisms of NT5C2 mutations driving thiopurine resistance in relapsed lymphoblastic leukemia
CL Dieck, G Tzoneva, F Forouhar, Z Carpenter, A Ambesi-Impiombato, ...
Cancer Cell 34 (1), 136-147. e6, 2018
462018
Tumor-specific HSP90 inhibition as a therapeutic approach in JAK-mutant acute lymphoblastic leukemias
Blood, 2015
42*2015
Leukemia-specific delivery of mutant NOTCH1 targeted therapy
G Roti, J Qi, S Kitara, M Sanchez-Martin, A Saur Conway, AC Varca, A Su, ...
Journal of Experimental Medicine 215 (1), 197-216, 2018
382018
The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia
CL Furness, MB Mansur, VJ Weston, L Ermini, FW van Delft, S Jenkinson, ...
Leukemia 32 (9), 1984-1993, 2018
312018
A phase 1, first-in-human study of IK-930, an oral TEAD inhibitor targeting the Hippo pathway in subjects with advanced solid tumors.
AW Tolcher, NJ Lakhani, M McKean, T Lingaraj, L Victor, ...
Journal of Clinical Oncology 40 (16_suppl), TPS3168-TPS3168, 2022
192022
Jak-STAT inhibition mediates romidepsin and mechlorethamine synergism in cutaneous T-cell lymphoma
JR Cortes, CC Patrone, SA Quinn, Y Gu, M Sanchez-Martin, A Mackey, ...
Journal of Investigative Dermatology 141 (12), 2908-2920. e7, 2021
182021
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