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Manjula Ramu
Manjula Ramu
Associate Research Scientist, Yale University
在 yale.edu 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Bromodomain and extra-terminal (BET) family proteins: New therapeutic targets in major diseases
B Padmanabhan, S Mathur, R Manjula, S Tripathi
Journal of biosciences 41, 295-311, 2016
1102016
SIRT1 and SIRT2 activity control in neurodegenerative diseases
R Manjula, K Anuja, FJ Alcain
Frontiers in pharmacology 11, 585821, 2021
1092021
A compendium of molecules involved in vector-pathogen interactions pertaining to malaria
SK Sreenivasamurthy, G Dey, M Ramu, M Kumar, MK Gupta, AK Mohanty, ...
Malaria journal 12, 1-7, 2013
602013
Assessment of ligand binding at a site relevant to SOD 1 oxidation and aggregation
R Manjula, GSA Wright, RW Strange, B Padmanabhan
FEBS letters 592 (10), 1725-1737, 2018
272018
Identification of new inhibitors for human SIRT1: an in-silico approach
B Padmanabhan, M Ramu, S Mathur, S Unni, S Thiyagarajan
Medicinal Chemistry 12 (4), 347-361, 2016
182016
A novel phenanthridionone based scaffold as a potential inhibitor of the BRD2 bromodomain: crystal structure of the complex
S Tripathi, S Mathur, P Deshmukh, R Manjula, B Padmanabhan
PloS one 11 (5), e0156344, 2016
142016
Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis
R Manjula, S Unni, GSA Wright, S Bharath MM, B Padmanabhan
Journal of Biomolecular Structure and Dynamics 37 (15), 3936-3946, 2019
132019
Design, synthesis, in-vitro evaluation and molecular docking studies of novel indole derivatives as inhibitors of SIRT1 and SIRT2
R Manjula, N Gokhale, S Unni, P Deshmukh, R Reddyrajula, ...
Bioorganic Chemistry 92, 103281, 2019
122019
A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase
E Chen, K Reiss, D Shah, R Manjula, B Allen, EL Murphy, JW Murphy, ...
Journal of Biological Chemistry 297 (3), 2021
112021
SIRT1 and SIRT2 activity control in neurodegenerative diseases. Front Pharmacol 11: 585821
R Manjula, K Anuja, FJ Alcain
62020
A cysteine variant at an allosteric site alters MIF dynamics and biological function in homo-and heterotrimeric assemblies
E Skeens, G Pantouris, D Shah, R Manjula, MJ Ombrello, NK Maluf, ...
Frontiers in Molecular Biosciences 9, 783669, 2022
52022
Role of AMP-activated protein kinase and sirtuins as antiaging proteins
M Ramu, SS Vishal, N Gogia
Anti-aging drug discovery on the basis of hallmarks of aging, 241-278, 2022
22022
Nanoantibiotics: The Next-Generation Antimicrobials
R Manjula, M Chavadi
Functional Bionanomaterials: From Biomolecules to Nanoparticles, 375-388, 2020
22020
Plant MDL proteins synergize with the cytokine MIF at CXCR2 and CXCR4 receptors in human cells
L Spiller, R Manjula, F Leissing, J Basquin, P Bourilhon, D Sinitski, ...
Science Signaling 16 (812), eadg2621, 2023
12023
Biotechnology of Microalgae: A Green Approach Towards Exploitation of Omega-3 Fatty Acids
R Manjula, M Chavadi
Phycobiotechnology, 307-323, 2021
12021
A Small Molecule Allele-selective Transcriptional Inhibitor of the MIF Immune Susceptibility Locus
J Li, L Leng, G Pantouris, R Manjula, M Piecychna, L Abriola, B Hu, ...
Journal of Biological Chemistry, 107443, 2024
2024
Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose
J Bloom, G Pantouris, M He, B Aljabari, L Mishra, R Manjula, A Parkins, ...
Molecular Medicine 30 (1), 43, 2024
2024
Engineering of the high-affinity chemokine CXCL13 to screen CXCR5 antagonists to treat cancer and autoimmune diseases
M Ramu, E Rosenberg, S Kartz, F Foss, EJ Lolis
Biophysical Journal 122 (3), 474a, 2023
2023
Structures of Arabidopsis thaliana MDL Proteins and Synergistic Effects with the Cytokine MIF on Human Receptors
L Spiller, R Manjula, F Leissing, J Basquin, P Bourilhon, D Sinitski, ...
bioRxiv, 2023.01. 30.525655, 2023
2023
Next-Generation Sequencing for Strain Tracking and Community Profiling of Food Microbes
G Pavan, M Chavadi, M Hanumanthappa, M Ramu
Global Food Safety, 207-230, 2023
2023
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