Bromodomain and extra-terminal (BET) family proteins: New therapeutic targets in major diseases B Padmanabhan, S Mathur, R Manjula, S Tripathi Journal of biosciences 41, 295-311, 2016 | 110 | 2016 |
SIRT1 and SIRT2 activity control in neurodegenerative diseases R Manjula, K Anuja, FJ Alcain Frontiers in pharmacology 11, 585821, 2021 | 109 | 2021 |
A compendium of molecules involved in vector-pathogen interactions pertaining to malaria SK Sreenivasamurthy, G Dey, M Ramu, M Kumar, MK Gupta, AK Mohanty, ... Malaria journal 12, 1-7, 2013 | 60 | 2013 |
Assessment of ligand binding at a site relevant to SOD 1 oxidation and aggregation R Manjula, GSA Wright, RW Strange, B Padmanabhan FEBS letters 592 (10), 1725-1737, 2018 | 27 | 2018 |
Identification of new inhibitors for human SIRT1: an in-silico approach B Padmanabhan, M Ramu, S Mathur, S Unni, S Thiyagarajan Medicinal Chemistry 12 (4), 347-361, 2016 | 18 | 2016 |
A novel phenanthridionone based scaffold as a potential inhibitor of the BRD2 bromodomain: crystal structure of the complex S Tripathi, S Mathur, P Deshmukh, R Manjula, B Padmanabhan PloS one 11 (5), e0156344, 2016 | 14 | 2016 |
Rational discovery of a SOD1 tryptophan oxidation inhibitor with therapeutic potential for amyotrophic lateral sclerosis R Manjula, S Unni, GSA Wright, S Bharath MM, B Padmanabhan Journal of Biomolecular Structure and Dynamics 37 (15), 3936-3946, 2019 | 13 | 2019 |
Design, synthesis, in-vitro evaluation and molecular docking studies of novel indole derivatives as inhibitors of SIRT1 and SIRT2 R Manjula, N Gokhale, S Unni, P Deshmukh, R Reddyrajula, ... Bioorganic Chemistry 92, 103281, 2019 | 12 | 2019 |
A structurally preserved allosteric site in the MIF superfamily affects enzymatic activity and CD74 activation in D-dopachrome tautomerase E Chen, K Reiss, D Shah, R Manjula, B Allen, EL Murphy, JW Murphy, ... Journal of Biological Chemistry 297 (3), 2021 | 11 | 2021 |
SIRT1 and SIRT2 activity control in neurodegenerative diseases. Front Pharmacol 11: 585821 R Manjula, K Anuja, FJ Alcain | 6 | 2020 |
A cysteine variant at an allosteric site alters MIF dynamics and biological function in homo-and heterotrimeric assemblies E Skeens, G Pantouris, D Shah, R Manjula, MJ Ombrello, NK Maluf, ... Frontiers in Molecular Biosciences 9, 783669, 2022 | 5 | 2022 |
Role of AMP-activated protein kinase and sirtuins as antiaging proteins M Ramu, SS Vishal, N Gogia Anti-aging drug discovery on the basis of hallmarks of aging, 241-278, 2022 | 2 | 2022 |
Nanoantibiotics: The Next-Generation Antimicrobials R Manjula, M Chavadi Functional Bionanomaterials: From Biomolecules to Nanoparticles, 375-388, 2020 | 2 | 2020 |
Plant MDL proteins synergize with the cytokine MIF at CXCR2 and CXCR4 receptors in human cells L Spiller, R Manjula, F Leissing, J Basquin, P Bourilhon, D Sinitski, ... Science Signaling 16 (812), eadg2621, 2023 | 1 | 2023 |
Biotechnology of Microalgae: A Green Approach Towards Exploitation of Omega-3 Fatty Acids R Manjula, M Chavadi Phycobiotechnology, 307-323, 2021 | 1 | 2021 |
A Small Molecule Allele-selective Transcriptional Inhibitor of the MIF Immune Susceptibility Locus J Li, L Leng, G Pantouris, R Manjula, M Piecychna, L Abriola, B Hu, ... Journal of Biological Chemistry, 107443, 2024 | | 2024 |
Iguratimod, an allosteric inhibitor of macrophage migration inhibitory factor (MIF), prevents mortality and oxidative stress in a murine model of acetaminophen overdose J Bloom, G Pantouris, M He, B Aljabari, L Mishra, R Manjula, A Parkins, ... Molecular Medicine 30 (1), 43, 2024 | | 2024 |
Engineering of the high-affinity chemokine CXCL13 to screen CXCR5 antagonists to treat cancer and autoimmune diseases M Ramu, E Rosenberg, S Kartz, F Foss, EJ Lolis Biophysical Journal 122 (3), 474a, 2023 | | 2023 |
Structures of Arabidopsis thaliana MDL Proteins and Synergistic Effects with the Cytokine MIF on Human Receptors L Spiller, R Manjula, F Leissing, J Basquin, P Bourilhon, D Sinitski, ... bioRxiv, 2023.01. 30.525655, 2023 | | 2023 |
Next-Generation Sequencing for Strain Tracking and Community Profiling of Food Microbes G Pavan, M Chavadi, M Hanumanthappa, M Ramu Global Food Safety, 207-230, 2023 | | 2023 |