Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues. CI Brannan, AS Perkins, KS Vogel, N Ratner, ML Nordlund, SW Reid, ... Genes & development 8 (9), 1019-1029, 1994 | 764 | 1994 |
Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis JE DeClue, AG Papageorge, JA Fletcher, SR Diehl, N Ratner, WC Vass, ... Cell 69 (2), 265-273, 1992 | 711 | 1992 |
Activity of selumetinib in neurofibromatosis type 1–related plexiform neurofibromas E Dombi, A Baldwin, LJ Marcus, MJ Fisher, B Weiss, AR Kim, P Whitcomb, ... New England Journal of Medicine 375 (26), 2550-2560, 2016 | 627 | 2016 |
Glycogen synthase kinase 3 phosphorylates kinesin light chains and negatively regulates kinesin‐based motility G Morfini, G Szebenyi, R Elluru, N Ratner, ST Brady The EMBO journal, 2002 | 513 | 2002 |
A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor N Ratner, SJ Miller Nature Reviews Cancer 15 (5), 290-301, 2015 | 477 | 2015 |
The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling RJ Shaw, JG Paez, M Curto, A Yaktine, WM Pruitt, I Saotome, JP O'Bryan, ... Developmental cell 1 (1), 63-72, 2001 | 414 | 2001 |
The protein product of the neurofibromatosis type 1 gene is expressed at highest abundance in neurons, Schwann cells, and oligodendrocytes MM Daston, H Scrable, M Nordlund, AK Sturbaum, LM Nissen, N Ratner Neuron 8 (3), 415-428, 1992 | 395 | 1992 |
MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors WJ Jessen, SJ Miller, E Jousma, J Wu, TA Rizvi, ME Brundage, D Eaves, ... The Journal of clinical investigation 123 (1), 340-347, 2013 | 352 | 2013 |
Cognitive function and academic performance in neurofibrornatosis 1: Consensus statement from the NF1 Cognitive Disorders Task Force KN North, V Riccardi, C Samango-Sprouse, R Ferner, B Moore, E Legius, ... Neurology 48 (4), 1121-1127, 1997 | 345 | 1997 |
Neurofibromin-deficient Schwann cells secrete a potent migratory stimulus for Nf1+/– mast cells Y Feng-Chun, DA Ingram, S Chen, CM Hingtgen, N Ratner, KR Monk, ... The Journal of clinical investigation 112 (12), 1851-1861, 2003 | 256 | 2003 |
Mechanisms and roles of axon-Schwann cell interactions G Corfas, MO Velardez, CP Ko, N Ratner, E Peles Journal of Neuroscience 24 (42), 9250-9260, 2004 | 255 | 2004 |
Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells J Wu, JP Williams, TA Rizvi, JJ Kordich, D Witte, D Meijer, ... Cancer cell 13 (2), 105-116, 2008 | 235 | 2008 |
Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues SJ Miller, F Rangwala, J Williams, P Ackerman, S Kong, AG Jegga, ... Cancer research 66 (5), 2584-2591, 2006 | 220 | 2006 |
Epidermal growth factor receptor expression in neurofibromatosis type 1–related tumors and NF1 animal models JE DeClue, S Heffelfinger, G Benvenuto, B Ling, S Li, W Rui, WC Vass, ... The Journal of clinical investigation 105 (9), 1233-1241, 2000 | 211 | 2000 |
Ruffling membrane, stress fiber, cell spreading and proliferation abnormalities in human Schwannoma cells PD Pelton, LS Sherman, TA Rizvi, MA Marchionni, P Wood, RA Friedman, ... Oncogene 17 (17), 2195-2209, 1998 | 206 | 1998 |
A neuronal cell surface heparan sulfate proteoglycan is required for dorsal root ganglion neuron stimulation of Schwann cell proliferation. N Ratner, RP Bunge, L Glaser The Journal of cell biology 101 (3), 744-754, 1985 | 202 | 1985 |
Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria SR Plotkin, JO Blakeley, DG Evans, CO Hanemann, TJM Hulsebos, ... American journal of medical genetics Part A 161 (3), 405-416, 2013 | 193 | 2013 |
S100 is present in developing chicken neurons and schwann cell and promotes motor neuron survival in vivo A Bhattacharyya, RW Oppenheim, D Prevette, BW Moore, R Brackenbury, ... Journal of neurobiology 23 (4), 451-466, 1992 | 192 | 1992 |
Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts LS Sherman, R Atit, T Rosenbaum, AD Cox, N Ratner Journal of Biological Chemistry 275 (39), 30740-30745, 2000 | 180 | 2000 |
Nf1-Deficient Mouse Schwann Cells Are Angiogenic and Invasive and Can Be Induced To Hyperproliferate: Reversion of Some Phenotypes by an Inhibitor of … HA Kim, B Ling, N Ratner Molecular and Cellular Biology 17 (2), 862-872, 1997 | 178 | 1997 |