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Philippe Billiald
Philippe Billiald
University Paris-Saclay
在 universite-paris-saclay.fr 的电子邮件经过验证
标题
引用次数
引用次数
年份
Safety and tolerability, pharmacokinetics, and pharmacodynamics of ACT017, an antiplatelet GPVI (glycoprotein VI) Fab: First-in-human healthy volunteer trial
C Voors-Pette, K Lebozec, P Dogterom, L Jullien, P Billiald, P Ferlan, ...
Arteriosclerosis, thrombosis, and vascular biology 39 (5), 956-964, 2019
1192019
The future of glycoprotein VI as an antithrombotic target
M Zahid, P Mangin, S Loyau, B Hechler, P Billiald, C Gachet, ...
Journal of Thrombosis and Haemostasis 10 (12), 2418-2427, 2012
1072012
Design, development and characterization of ACT017, a humanized Fab that blocks platelet's glycoprotein VI function without causing bleeding risks
K Lebozec, M Jandrot-Perrus, G Avenard, O Favre-Bulle, P Billiald
MAbs 9 (6), 945-958, 2017
952017
Non-invasive molecular imaging of fibrosis using a collagen-targeted peptidomimetic of the platelet collagen receptor glycoprotein VI
J Muzard, L Sarda-Mantel, S Loyau, A Meulemans, L Louedec, ...
PloS one 4 (5), e5585, 2009
862009
A recombinant single-chain antibody fragment that neutralizes toxin II from the venom of the scorpion Androctonus australis hector
M Mousli, C Devaux, H Rochat, M Goyffon, P Billiald
FEBS letters 442 (2-3), 183-188, 1999
661999
Construction and functional evaluation of a single‐chain antibody fragment that neutralizes toxin AahI from the venom of the scorpion Androctonus australis hector
C Devaux, E Moreau, M Goyffon, H Rochat, P Billiald
European journal of biochemistry 268 (3), 694-702, 2001
652001
Approach to the direct intramolecular localization of antigenic determinants in Androctonus australis hemocyanin with monoclonal antibodies by molecular immunoelectron microscopy
J Lamy, J Lamy, P Billiald, PY Sizaret, G Cave, J Frank, G Motta
Biochemistry 24 (20), 5532-5542, 1985
631985
Engineering venom’s toxin-neutralizing antibody fragments and its therapeutic potential
LM Alvarenga, M Zahid, A di Tommaso, MO Juste, N Aubrey, P Billiald, ...
Toxins 6 (8), 2541-2567, 2014
622014
Quaternary structure of Limulus polyphemus hemocyanin
J Lamy, J Lamy, PY Sizaret, P Billiald, P Jolles, J Jolles, RJ Feldmann, ...
Biochemistry 22 (24), 5573-5583, 1983
581983
Design and humanization of a murine scFv that blocks human platelet glycoprotein VI in vitro
J Muzard, M Bouabdelli, M Zahid, V Ollivier, JJ Lacapère, ...
The FEBS Journal 276 (15), 4207-4222, 2009
502009
Design and evaluation of a diabody to improve protection against a potent scorpion neurotoxin
N Aubrey, C Devaux, PY Sizaret, H Rochat, M Goyffon, P Billiald
Cellular and Molecular Life Sciences CMLS 60, 617-628, 2003
492003
Envenomations VI. Scorpionism in Africa
M Goyffon, P Billiald
Medecine Tropicale: Revue du Corps de Sante Colonial 67 (5), 439-446, 2007
472007
Grafting of protein L-binding activity onto recombinant antibody fragments
J Muzard, S Adi-Bessalem, M Juste, F Laraba-Djebari, N Aubrey, ...
Analytical biochemistry 388 (2), 331-338, 2009
442009
scFv single chain antibody variable fragment as inverse agonist of the β2-adrenergic receptor
JC Peter, P Eftekhari, P Billiald, G Wallukat, J Hoebeke
Journal of Biological Chemistry 278 (38), 36740-36747, 2003
422003
Creation of recombinant antigen-binding molecules derived from hybridomas secreting specific antibodies
C Fields, D O'connell, S Xiao, GU Lee, P Billiald, J Muzard
Nature protocols 8 (6), 1125-1148, 2013
392013
A method to confer Protein L binding ability to any antibody fragment
Z Lakhrif, M Pugnière, C Henriquet, A Di Tommaso, I Dimier-Poisson, ...
MAbs 8 (2), 379-388, 2016
382016
Quality and cost assessment of a recombinant antibody fragment produced from mammalian, yeast and prokaryotic host cells: A case study prior to pharmaceutical development
K Lebozec, M Jandrot-Perrus, G Avenard, O Favre-Bulle, P Billiald
New biotechnology 44, 31-40, 2018
322018
Population pharmacokinetic/pharmacodynamic modeling of glenzocimab (ACT017) a glycoprotein VI inhibitor of collagen‐induced platelet aggregation
L Renaud, K Lebozec, C Voors‐Pette, P Dogterom, P Billiald, ...
The Journal of Clinical Pharmacology 60 (9), 1198-1208, 2020
302020
Targeting platelet GPVI with glenzocimab: a novel mechanism for inhibition
P Billiald, A Slater, M Welin, JC Clark, S Loyau, M Pugnière, IG Jiacomini, ...
Blood Advances 7 (7), 1258-1268, 2023
292023
Using a recombinant bispecific antibody to block Na+-channel toxins protects against experimental scorpion envenoming
M Juste, MF Martin-Eauclaire, C Devaux, P Billiald, N Aubrey
Cellular and molecular life sciences 64 (2), 206-218, 2007
292007
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