The microbiome and butyrate regulate energy metabolism and autophagy in the mammalian colon DR Donohoe, N Garge, X Zhang, W Sun, TM O'Connell, MK Bunger, ... Cell metabolism 13 (5), 517-526, 2011 | 1888 | 2011 |
A class of reactive acyl-CoA species reveals the non-enzymatic origins of protein acylation GR Wagner, DP Bhatt, TM O’Connell, JW Thompson, LG Dubois, ... Cell metabolism 25 (4), 823-837. e8, 2017 | 244 | 2017 |
Cachexia induced by cancer and chemotherapy yield distinct perturbations to energy metabolism F Pin, R Barreto, ME Couch, A Bonetto, TM O'Connell Journal of cachexia, sarcopenia and muscle 10 (1), 140-154, 2019 | 193 | 2019 |
Use of pharmaco‐metabonomics for early prediction of acetaminophen‐induced hepatotoxicity in humans JH Winnike, Z Li, FA Wright, JM Macdonald, TM O'connell, PB Watkins Clinical Pharmacology & Therapeutics 88 (1), 45-51, 2010 | 180 | 2010 |
Antibiotic-induced changes in the microbiota disrupt redox dynamics in the gut AT Reese, EH Cho, B Klitzman, SP Nichols, NA Wisniewski, MM Villa, ... Elife 7, e35987, 2018 | 158 | 2018 |
Metabolomic profiling reveals mitochondrial-derived lipid biomarkers that drive obesity-associated inflammation BP Sampey, AJ Freemerman, J Zhang, PF Kuan, JA Galanko, ... PloS one 7 (6), e38812, 2012 | 141 | 2012 |
The complex role of branched chain amino acids in diabetes and cancer TM O’Connell Metabolites 3 (4), 931-945, 2013 | 138 | 2013 |
Tumor-derived IL-6 and trans-signaling among tumor, fat, and muscle mediate pancreatic cancer cachexia JE Rupert, A Narasimhan, DHA Jengelley, Y Jiang, J Liu, E Au, ... Journal of Experimental Medicine 218 (6), e20190450, 2021 | 126 | 2021 |
Metabolomic analysis of bronchoalveolar lavage fluid from cystic fibrosis patients JE Wolak, CR Esther Jr, TM O’Connell Biomarkers 14 (1), 55-60, 2009 | 125 | 2009 |
Microbial nitrogen limitation in the mammalian large intestine AT Reese, FC Pereira, A Schintlmeister, D Berry, M Wagner, LP Hale, ... Nature microbiology 3 (12), 1441-1450, 2018 | 124 | 2018 |
Acetaminophen dosing of humans results in blood transcriptome and metabolome changes consistent with impaired oxidative phosphorylation RD Fannin, M Russo, TM O'Connell, K Gerrish, JH Winnike, J Macdonald, ... Hepatology 51 (1), 227-236, 2010 | 114 | 2010 |
The application of metabonomics to predict drug‐induced liver injury TM O'Connell, PB Watkins Clinical Pharmacology & Therapeutics 88 (3), 394-399, 2010 | 90 | 2010 |
Disrupted maturation of the microbiota and metabolome among extremely preterm infants with postnatal growth failure NE Younge, CB Newgard, CM Cotten, RN Goldberg, MJ Muehlbauer, ... Scientific reports 9 (1), 8167, 2019 | 88 | 2019 |
1H Nuclear Magnetic Resonance Metabolomics Analysis Identifies Novel Urinary Biomarkers for Lung Function JL McClay, DE Adkins, NG Isern, TM O’Connell, JB Wooten, BK Zedler, ... Journal of proteome research 9 (6), 3083-3090, 2010 | 88 | 2010 |
Effects of a prolonged standardized diet on normalizing the human metabolome JH Winnike, MG Busby, PB Watkins, TM O’Connell The American journal of clinical nutrition 90 (6), 1496-1501, 2009 | 88 | 2009 |
Metabolomic profiling of a modified alcohol liquid diet model for liver injury in the mouse uncovers new markers of disease BU Bradford, TM O'Connell, J Han, O Kosyk, S Shymonyak, PK Ross, ... Toxicology and applied pharmacology 232 (2), 236-243, 2008 | 80 | 2008 |
Recent advances in metabolomics in oncology. TM O'Connell Bioanalysis 4 (4), 431-451, 2012 | 75 | 2012 |
The application of micro-coil NMR probe technology to metabolomics of urine and serum JH Grimes, TM O’Connell Journal of biomolecular NMR 49, 297-305, 2011 | 69 | 2011 |
A comparison of transcriptomic and metabonomic technologies for identifying biomarkers predictive of two-year rodent cancer bioassays RS Thomas, TM O'Connell, L Pluta, RD Wolfinger, L Yang, TJ Page Toxicological Sciences 96 (1), 40-46, 2007 | 67 | 2007 |
A role for gut microbiota in host niche differentiation LK Greene, CV Williams, RE Junge, KL Mahefarisoa, T Rajaonarivelo, ... The ISME Journal 14 (7), 1675-1687, 2020 | 66 | 2020 |