Menadione-induced reactive oxygen species generation via redox cycling promotes apoptosis of murine pancreatic acinar cells DN Criddle, S Gillies, HK Baumgartner-Wilson, M Jaffar, EC Chinje, ... Journal of Biological Chemistry 281 (52), 40485-40492, 2006 | 400 | 2006 |
Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP R Mukherjee, OA Mareninova, IV Odinokova, W Huang, J Murphy, ... Gut 65 (8), 1333-1346, 2016 | 240 | 2016 |
Inhibitors of ORAI1 prevent cytosolic calcium-associated injury of human pancreatic acinar cells and acute pancreatitis in 3 mouse models L Wen, S Voronina, MA Javed, M Awais, P Szatmary, D Latawiec, ... Gastroenterology 149 (2), 481-492. e7, 2015 | 229 | 2015 |
Fatty acid ethyl ester synthase inhibition ameliorates ethanol-induced Ca2+-dependent mitochondrial dysfunction and acute pancreatitis W Huang, DM Booth, MC Cane, M Chvanov, MA Javed, VL Elliott, ... Gut 63 (8), 1313-1324, 2014 | 186 | 2014 |
Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry CM Walsh, M Chvanov, LP Haynes, OH Petersen, AV Tepikin, ... Biochemical Journal 425 (1), 159-168, 2010 | 183 | 2010 |
Direct activation of cytosolic Ca2+ signaling and enzyme secretion by cholecystokinin in human pancreatic acinar cells JA Murphy, DN Criddle, M Sherwood, M Chvanov, R Mukherjee, ... Gastroenterology 135 (2), 632-641, 2008 | 176 | 2008 |
Modulation of calcium signalling by mitochondria C Walsh, S Barrow, S Voronina, M Chvanov, OH Petersen, A Tepikin Biochimica et Biophysica Acta (BBA)-Bioenergetics 1787 (11), 1374-1382, 2009 | 174 | 2009 |
Caffeine protects against experimental acute pancreatitis by inhibition of inositol 1, 4, 5-trisphosphate receptor-mediated Ca2+ release W Huang, MC Cane, R Mukherjee, P Szatmary, X Zhang, V Elliott, ... Gut 66 (2), 301-313, 2017 | 115 | 2017 |
Caspase-8-mediated apoptosis induced by oxidative stress is independent of the intrinsic pathway and dependent on cathepsins HK Baumgartner, JV Gerasimenko, C Thorne, LH Ashurst, SL Barrow, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 293 (1 …, 2007 | 100 | 2007 |
Free radicals and the pancreatic acinar cells: role in physiology and pathology M Chvanov, OH Petersen, A Tepikin Philosophical Transactions of the Royal Society B: Biological Sciences 360 …, 2005 | 99 | 2005 |
Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift JA Armstrong, NJ Cash, Y Ouyang, JC Morton, M Chvanov, D Latawiec, ... Journal of Biological Chemistry 293 (21), 8032-8047, 2018 | 85 | 2018 |
Calcium‐dependent release of NO from intracellular S‐nitrosothiols M Chvanov, OV Gerasimenko, OH Petersen, AV Tepikin The EMBO journal 25 (13), 3024-3032, 2006 | 63 | 2006 |
ATP depletion induces translocation of STIM1 to puncta and formation of STIM1–ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP M Chvanov, CM Walsh, LP Haynes, SG Voronina, G Lur, ... Pflügers Archiv-European Journal of Physiology 457, 505-517, 2008 | 55 | 2008 |
The role of Ca2+ influx in endocytic vacuole formation in pancreatic acinar cells S Voronina, D Collier, M Chvanov, B Middlehurst, AJ Beckett, IA Prior, ... Biochemical Journal 465 (3), 405-412, 2015 | 51 | 2015 |
Expression of human cationic trypsinogen (PRSS1) in murine acinar cells promotes pancreatitis and apoptotic cell death T Athwal, W Huang, R Mukherjee, D Latawiec, M Chvanov, R Clarke, ... Cell death & disease 5 (4), e1165-e1165, 2014 | 47 | 2014 |
Effects of the mitochondria‐targeted antioxidant mitoquinone in murine acute pancreatitis W Huang, N Cash, L Wen, P Szatmary, R Mukherjee, J Armstrong, ... Mediators of Inflammation 2015 (1), 901780, 2015 | 43 | 2015 |
TRO40303 ameliorates alcohol-induced pancreatitis through reduction of fatty acid ethyl ester–induced mitochondrial injury and necrotic cell death MA Javed, L Wen, M Awais, D Latawiec, W Huang, M Chvanov, ... Pancreas 47 (1), 18-24, 2018 | 40 | 2018 |
Mechanisms of Pancreatic Injury Induced by Basic Amino Acids Differ Between L-Arginine, L-Ornithine, and L-Histidine X Zhang, T Jin, N Shi, L Yao, X Yang, C Han, L Wen, D Du, P Szatmary, ... Frontiers in Physiology 9, 1922, 2019 | 36 | 2019 |
Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis M Chvanov, F De Faveri, D Moore, MW Sherwood, M Awais, S Voronina, ... The Journal of physiology 596 (13), 2547-2564, 2018 | 34 | 2018 |
Novel lipophilic probe for detecting near-membrane reactive oxygen species responses and its application for studies of pancreatic acinar cells: effects of pyocyanin and L … M Chvanov, W Huang, T Jin, L Wen, J Armstrong, V Elliot, B Alston, ... Antioxidants & redox signaling 22 (6), 451-464, 2015 | 24 | 2015 |