Principle and design of pseudo-natural products G Karageorgis, DJ Foley, L Laraia, H Waldmann Nature Chemistry 12 (3), 227-235, 2020 | 164 | 2020 |
Pseudo natural products—chemical evolution of natural product structure G Karageorgis, DJ Foley, L Laraia, S Brakmann, H Waldmann Angewandte Chemie International Edition 60 (29), 15705-15723, 2021 | 83 | 2021 |
A unified lead-oriented synthesis of over fifty molecular scaffolds RG Doveston, P Tosatti, M Dow, DJ Foley, HY Li, AJ Campbell, D House, ... Organic & biomolecular chemistry 13 (3), 859-865, 2015 | 81 | 2015 |
Evaluating new chemistry to drive molecular discovery: fit for purpose? DJ Foley, A Nelson, SP Marsden Angewandte Chemie International Edition 55 (44), 13650-13657, 2016 | 79 | 2016 |
A systematic approach to diverse, lead-like scaffolds from α, α-disubstituted amino acids DJ Foley, RG Doveston, I Churcher, A Nelson, SP Marsden Chemical communications 51 (56), 11174-11177, 2015 | 70 | 2015 |
Natural product fragment combination to performance-diverse pseudo-natural products M Grigalunas, A Burhop, S Zinken, A Pahl, JM Gally, N Wild, Y Mantel, ... Nature Communications 12 (1), 1883, 2021 | 63 | 2021 |
Synthesis and Demonstration of the Biological Relevance of sp3‐rich Scaffolds Distantly Related to Natural Product Frameworks DJ Foley, PGE Craven, PM Collins, RG Doveston, A Aimon, R Talon, ... Chemistry–A European Journal 23 (60), 15227-15232, 2017 | 63 | 2017 |
Emergent synthetic methods for the modular advancement of sp 3-rich fragments MJ Caplin, DJ Foley Chemical Science 12 (13), 4646-4660, 2021 | 57 | 2021 |
Image‐based morphological profiling identifies a lysosomotropic, Iron‐sequestering autophagy inhibitor L Laraia, G Garivet, DJ Foley, N Kaiser, S Müller, S Zinken, T Pinkert, ... Angewandte Chemie International Edition 59 (14), 5721-5729, 2020 | 51 | 2020 |
Ketones as strategic building blocks for the synthesis of natural product-inspired compounds DJ Foley, H Waldmann Chemical Society Reviews 51 (10), 4094-4120, 2022 | 50 | 2022 |
Phenotyping reveals targets of a pseudo‐Natural‐product autophagy inhibitor DJ Foley, S Zinken, D Corkery, L Laraia, A Pahl, YW Wu, H Waldmann Angewandte Chemie International Edition 59 (30), 12470-12476, 2020 | 47 | 2020 |
Construction of a Shape‐Diverse Fragment Set: Design, Synthesis and Screen against Aurora‐A Kinase R Zhang, PJ McIntyre, PM Collins, DJ Foley, C Arter, F von Delft, R Bayliss, ... Chemistry–A European Journal 25 (27), 6831-6839, 2019 | 30 | 2019 |
Carbolithiation of S-Alkenyl-N-aryl Thiocarbamates: Carbanion Arylation in a Connective Route to Tertiary Thiols D Castagnolo, DJ Foley, H Berber, R Luisi, J Clayden Organic letters 15 (9), 2116-2119, 2013 | 25 | 2013 |
Realisation of small molecule libraries based on frameworks distantly related to natural products A Aimon, G Karageorgis, J Masters, M Dow, PGE Craven, M Ohsten, ... Organic & biomolecular chemistry 16 (17), 3160-3167, 2018 | 21 | 2018 |
Access to 3D Alicyclic Amine-Containing Fragments through Transannular C–H Arylation M Lee, A Adams, PB Cox, MS Sanford Synlett 30 (04), 417-422, 2019 | 17 | 2019 |
Evaluierung neuer Reaktionen zur Steuerung der Wirkstoff‐Forschung: ein Eignungstest DJ Foley, A Nelson, SP Marsden Angewandte Chemie 128 (44), 13850-13857, 2016 | 11 | 2016 |
Enantioselective synthesis of hydantoins by chiral acid-catalysed condensation of glyoxals and ureas S Aryal, CA Hone, MIJ Polson, DJ Foley Chemical Science 14 (29), 7905-7912, 2023 | 7 | 2023 |
Discovery of 2, 4-dimethoxypyridines as novel autophagy inhibitors L Robke, T Rodrigues, P Schröder, DJ Foley, GJL Bernardes, L Laraia, ... Tetrahedron 74 (35), 4531-4537, 2018 | 7 | 2018 |
Exploring the roles of the Cdc2-like kinases in cancers AC Blackie, DJ Foley Bioorganic & Medicinal Chemistry 70, 116914, 2022 | 5 | 2022 |
Thermal proteome profiling efficiently identifies ribosome destabilizing oxazolidinones C Nöcker, N Kaiser, D Foley, S Sievers, P Janning, H Waldmann, L Laraia Tetrahedron 87, 132118, 2021 | 3 | 2021 |