| Mutational signature in colorectal cancer caused by genotoxic pks+E. coli C Pleguezuelos-Manzano, J Puschhof, A Rosendahl Huber, A van Hoeck, ... Nature 580 (7802), 269-273, 2020 | 732 | 2020 |
| High-resolution mRNA and secretome atlas of human enteroendocrine cells J Beumer, J Puschhof, J Bauzá-Martinez, A Martínez-Silgado, ... Cell 181 (6), 1291-1306. e19, 2020 | 147 | 2020 |
| Intestinal organoid cocultures with microbes J Puschhof, C Pleguezuelos-Manzano, A Martinez-Silgado, N Akkerman, ... Nature protocols 16 (10), 4633-4649, 2021 | 137 | 2021 |
| Establishment and culture of human intestinal organoids derived from adult stem cells C Pleguezuelos‐Manzano, J Puschhof, S van den Brink, V Geurts, ... Current protocols in immunology 130 (1), e106, 2020 | 116 | 2020 |
| Organoids and organs-on-chips: Insights into human gut-microbe interactions J Puschhof, C Pleguezuelos-Manzano, H Clevers Cell host & microbe 29 (6), 867-878, 2021 | 108 | 2021 |
| Next-generation surrogate Wnts support organoid growth and deconvolute frizzled pleiotropy in vivo Y Miao, A Ha, W de Lau, K Yuki, AJM Santos, C You, MH Geurts, ... Cell Stem Cell 27 (5), 840-851. e6, 2020 | 98 | 2020 |
| Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids MH Geurts, E de Poel, C Pleguezuelos-Manzano, R Oka, L Carrillo, ... Life science alliance 4 (10), 2021 | 92 | 2021 |
| A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses J Beumer, MH Geurts, MM Lamers, J Puschhof, J Zhang, J van der Vaart, ... Nature communications 12 (1), 5498, 2021 | 70 | 2021 |
| Colon tumors in enterotoxigenic Bacteroides fragilis (ETBF)-colonized mice do not display a unique mutational signature but instead possess host-dependent alterations in the … J Allen, A Rosendahl Huber, C Pleguezuelos-Manzano, J Puschhof, S Wu, ... Microbiology spectrum 10 (3), e01055-22, 2022 | 24 | 2022 |
| Genomics England Research C C Pleguezuelos-Manzano, J Puschhof, A Rosendahl Huber, A van Hoeck, ... Garcia KC, Top J, Willems RJL, Giannakis M, Bonnet R, Quirke P, Meyerson M …, 2020 | 12 | 2020 |
| Intestinal region-specific Wnt signalling profiles reveal interrelation between cell identity and oncogenic pathway activity in cancer development RS Adam, SM van Neerven, C Pleguezuelos-Manzano, S Simmini, ... Cancer cell international 20, 1-15, 2020 | 11 | 2020 |
| Evaluating CRISPR-based Prime Editing for cancer modeling and CFTR repair in intestinal organoids MH Geurts, E de Poel, C Pleguezuelos-Manzano, L Carrillo, ... bioRxiv, 2020.10. 05.325837, 2020 | 10 | 2020 |
| A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses. Nat Commun 12: 5498 J Beumer, MH Geurts, MM Lamers, J Puschhof, J Zhang, J van der Vaart, ... | 8 | 2021 |
| Gut microbiota in colorectal cancer: associations, mechanisms, and clinical approaches C Pleguezuelos-Manzano, J Puschhof, H Clevers Annual Review of Cancer Biology 6 (1), 65-84, 2022 | 7 | 2022 |
| Comprehensive single-cell genome analysis at nucleotide resolution using the PTA Analysis Toolbox S Middelkamp, F Manders, F Peci, MJ van Roosmalen, DM González, ... Cell genomics 3 (9), 2023 | 4 | 2023 |
| Transcriptomic profile comparison reveals conservation of ionocytes across multiple organs C Pou Casellas, C Pleguezuelos-Manzano, MB Rookmaaker, ... Scientific reports 13 (1), 3516, 2023 | 4 | 2023 |
| DNA damage triggers squamous metaplasia in human lung and mammary cells via mitotic checkpoints LS Juan, A Freije, N Sanz-Gómez, B Jiménez-Matías, ... Cell death discovery 9 (1), 21, 2023 | 4 | 2023 |
| A bacterial mutational footprint in colorectal cancer genomes A Rosendahl Huber, C Pleguezuelos-Manzano, J Puschhof British Journal of Cancer 124 (11), 1751-1753, 2021 | 4 | 2021 |
| Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer AR Huber, C Pleguezuelos-Manzano, J Puschhof, J Ubels, C Boot, ... Cancer Cell 42 (3), 487-496. e6, 2024 | 3 | 2024 |
| Intestine-on-chip enhances nutrient and drug metabolism and maturation of iPSC-derived intestinal epithelial cells relative to organoids and Transwells R Moerkens, J Mooiweer, E Smits, M Berg, AD Ramirez Sanchez, ... bioRxiv, 2024.06. 30.601390, 2024 | | 2024 |
