Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice R Channappanavar, AR Fehr, R Vijay, M Mack, J Zhao, DK Meyerholz, ... Cell host & microbe 19 (2), 181-193, 2016 | 1509 | 2016 |
Severe acute respiratory syndrome coronavirus infection causes neuronal death in the absence of encephalitis in mice transgenic for human ACE2 J Netland, DK Meyerholz, S Moore, M Cassell, S Perlman Journal of virology 82 (15), 7264-7275, 2008 | 1441 | 2008 |
Sex-based differences in susceptibility to severe acute respiratory syndrome coronavirus infection R Channappanavar, C Fett, M Mack, PP Ten Eyck, DK Meyerholz, ... The Journal of Immunology 198 (10), 4046-4053, 2017 | 939 | 2017 |
Lethal Infection of K18-hACE2 Mice Infected with Severe Acute Respiratory Syndrome Coronavirus PB McCray Jr, L Pewe, C Wohlford-Lenane, M Hickey, L Manzel, L Shi, ... Journal of virology 81 (2), 813-821, 2007 | 923 | 2007 |
Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn Pigs CS Rogers, DA Stoltz, DK Meyerholz, LS Ostedgaard, T Rokhlina, PJ Taft, ... Science 321 (5897), 1837-1841, 2008 | 847 | 2008 |
Origins of cystic fibrosis lung disease DA Stoltz, DK Meyerholz, MJ Welsh New England Journal of Medicine 372 (4), 351-362, 2015 | 723 | 2015 |
Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors JP Dassie, X Liu, GS Thomas, RM Whitaker, KW Thiel, KR Stockdale, ... Nature biotechnology 27 (9), 839-846, 2009 | 670 | 2009 |
Principles for valid histopathologic scoring in research KN Gibson-Corley, AK Olivier, DK Meyerholz Veterinary pathology 50 (6), 1007-1015, 2013 | 601 | 2013 |
IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes R Channappanavar, AR Fehr, J Zheng, C Wohlford-Lenane, ... The Journal of clinical investigation 129 (9), 3625-3639, 2019 | 570 | 2019 |
Cystic fibrosis pigs develop lung disease and exhibit defective bacterial eradication at birth DA Stoltz, DK Meyerholz, AA Pezzulo, S Ramachandran, MP Rogan, ... Science translational medicine 2 (29), 29ra31-29ra31, 2010 | 556 | 2010 |
Middle East respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4 K Li, C Wohlford-Lenane, S Perlman, J Zhao, AK Jewell, LR Reznikov, ... The Journal of infectious diseases 213 (5), 712-722, 2016 | 503 | 2016 |
Airway memory CD4+ T cells mediate protective immunity against emerging respiratory coronaviruses J Zhao, J Zhao, AK Mangalam, R Channappanavar, C Fett, DK Meyerholz, ... Immunity 44 (6), 1379-1391, 2016 | 491 | 2016 |
Virus-specific memory CD8 T cells provide substantial protection from lethal severe acute respiratory syndrome coronavirus infection R Channappanavar, C Fett, J Zhao, DK Meyerholz, S Perlman Journal of virology 88 (19), 11034-11044, 2014 | 449 | 2014 |
T-cell immunoglobulin and mucin domain 1 (TIM-1) is a receptor for Zaire Ebolavirus and Lake Victoria Marburgvirus AS Kondratowicz, NJ Lennemann, PL Sinn, RA Davey, CL Hunt, ... Proceedings of the National Academy of Sciences 108 (20), 8426-8431, 2011 | 430 | 2011 |
Generation of a broadly useful model for COVID-19 pathogenesis, vaccination, and treatment J Sun, Z Zhuang, J Zheng, K Li, RLY Wong, D Liu, J Huang, J He, A Zhu, ... Cell 182 (3), 734-743. e5, 2020 | 407 | 2020 |
Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis X Sun, H Sui, JT Fisher, Z Yan, X Liu, HJ Cho, NS Joo, Y Zhang, W Zhou, ... The Journal of clinical investigation 120 (9), 3149-3160, 2010 | 389 | 2010 |
COVID-19 treatments and pathogenesis including anosmia in K18-hACE2 mice J Zheng, LYR Wong, K Li, AK Verma, ME Ortiz, C Wohlford-Lenane, ... Nature 589 (7843), 603-607, 2021 | 349 | 2021 |
Broad-Spectrum In Vitro Activity and In Vivo Efficacy of the Antiviral Protein Griffithsin against Emerging Viruses of the Family Coronaviridae BR O'Keefe, B Giomarelli, DL Barnard, SR Shenoy, PKS Chan, ... Journal of virology 84 (5), 2511-2521, 2010 | 332 | 2010 |
Airway acidification initiates host defense abnormalities in cystic fibrosis mice VS Shah, DK Meyerholz, XX Tang, L Reznikov, M Abou Alaiwa, SE Ernst, ... Science 351 (6272), 503-507, 2016 | 295 | 2016 |
The porcine lung as a potential model for cystic fibrosis CS Rogers, WM Abraham, KA Brogden, JF Engelhardt, JT Fisher, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 295 (2 …, 2008 | 283 | 2008 |