Genomic atlas of the human plasma proteome BB Sun, JC Maranville, JE Peters, D Stacey, JR Staley, J Blackshaw, ... Nature 558 (7708), 73-79, 2018 | 1442 | 2018 |
PhenoScanner V2: an expanded tool for searching human genotype–phenotype associations MA Kamat, JA Blackshaw, R Young, P Surendran, S Burgess, J Danesh, ... Bioinformatics 35 (22), 4851-4853, 2019 | 1335 | 2019 |
Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits E Evangelou, HR Warren, D Mosen-Ansorena, B Mifsud, R Pazoki, H Gao, ... Nature genetics 50 (10), 1412-1425, 2018 | 1204 | 2018 |
PhenoScanner: a database of human genotype–phenotype associations JR Staley, J Blackshaw, MA Kamat, S Ellis, P Surendran, BB Sun, ... Bioinformatics 32 (20), 3207-3209, 2016 | 1193 | 2016 |
Rare and low-frequency coding variants alter human adult height E Marouli, M Graff, C Medina-Gomez, KS Lo, AR Wood, TR Kjaer, RS Fine, ... Nature 542 (7640), 186-190, 2017 | 654 | 2017 |
Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk HR Warren, E Evangelou, CP Cabrera, H Gao, M Ren, B Mifsud, I Ntalla, ... Nature genetics 49 (3), 403-415, 2017 | 599 | 2017 |
Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease P Zanoni, SA Khetarpal, DB Larach, WF Hancock-Cerutti, JS Millar, ... Science 351 (6278), 1166-1171, 2016 | 568 | 2016 |
Exome-wide association study of plasma lipids in> 300,000 individuals DJ Liu, GM Peloso, H Yu, AS Butterworth, X Wang, A Mahajan, ... Nature genetics 49 (12), 1758-1766, 2017 | 545 | 2017 |
Association of LPA variants with risk of coronary disease and the implications for lipoprotein (a)-lowering therapies: a Mendelian randomization analysis S Burgess, BA Ference, JR Staley, DF Freitag, AM Mason, SF Nielsen, ... JAMA cardiology 3 (7), 619-627, 2018 | 487 | 2018 |
The polygenic and monogenic basis of blood traits and diseases D Vuckovic, EL Bao, P Akbari, CA Lareau, A Mousas, T Jiang, MH Chen, ... Cell 182 (5), 1214-1231. e11, 2020 | 463 | 2020 |
Trans-ethnic and ancestry-specific blood-cell genetics in 746,667 individuals from 5 global populations MH Chen, LM Raffield, A Mousas, S Sakaue, JE Huffman, A Moscati, ... Cell 182 (5), 1198-1213. e14, 2020 | 426 | 2020 |
Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes A Mahajan, J Wessel, SM Willems, W Zhao, NR Robertson, AY Chu, ... Nature genetics 50 (4), 559-571, 2018 | 423 | 2018 |
Coding Variation in ANGPTL4, LPL, and SVEP1 and the Risk of Coronary Disease Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia Investigators New England Journal of Medicine 374 (12), 1134-1144, 2016 | 400 | 2016 |
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals L Folkersen, S Gustafsson, Q Wang, DH Hansen, ÅK Hedman, A Schork, ... Nature metabolism 2 (10), 1135-1148, 2020 | 396 | 2020 |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals A Giri, JN Hellwege, JM Keaton, J Park, C Qiu, HR Warren, ES Torstenson, ... Nature genetics 51 (1), 51-62, 2019 | 376 | 2019 |
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity V Turcot, Y Lu, HM Highland, C Schurmann, AE Justice, RS Fine, ... Nature genetics 50 (1), 26-41, 2018 | 339 | 2018 |
Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension P Surendran, F Drenos, R Young, H Warren, JP Cook, AK Manning, ... Nature genetics 48 (10), 1151-1161, 2016 | 324 | 2016 |
Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms JMM Howson, W Zhao, DR Barnes, WK Ho, R Young, DS Paul, LL Waite, ... Nature genetics 49 (7), 1113-1119, 2017 | 300 | 2017 |
Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease W Zhao, A Rasheed, E Tikkanen, JJ Lee, AS Butterworth, JMM Howson, ... Nature genetics 49 (10), 1450-1457, 2017 | 264 | 2017 |
Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci C Liu, AT Kraja, JA Smith, JA Brody, N Franceschini, JC Bis, K Rice, ... Nature genetics 48 (10), 1162-1170, 2016 | 263 | 2016 |