Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking J Weischenfeldt, T Dubash, AP Drainas, BR Mardin, Y Chen, AM Stütz, ... Nature genetics 49 (1), 65-74, 2017 | 384 | 2017 |
A cell‐based model system links chromothripsis with hyperploidy BR Mardin, AP Drainas, SM Waszak, J Weischenfeldt, M Isokane, ... Molecular systems biology 11 (9), 828, 2015 | 144 | 2015 |
The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D AC Chaikovsky, C Li, EE Jeng, S Loebell, MC Lee, CW Murray, R Cheng, ... Nature 592 (7856), 794-798, 2021 | 87 | 2021 |
Unbiased proteomic profiling uncovers a targetable GNAS/PKA/PP2A axis in small cell lung cancer stem cells GL Coles, S Cristea, JT Webber, RS Levin, SM Moss, A He, J Sangodkar, ... Cancer Cell 38 (1), 129-143. e7, 2020 | 69 | 2020 |
The MEK5–ERK5 kinase axis controls lipid metabolism in small-cell lung cancer S Cristea, GL Coles, D Hornburg, M Gershkovitz, J Arand, S Cao, T Sen, ... Cancer Research 80 (6), 1293-1303, 2020 | 62 | 2020 |
Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect Y Nishiga, AP Drainas, M Baron, D Bhattacharya, AA Barkal, Y Ahrari, ... Nature Cancer 3 (11), 1351-1366, 2022 | 57 | 2022 |
A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs YT Shue, AP Drainas, NY Li, SM Pearsall, D Morgan, N Sinnott-Armstrong, ... Nature communications 13 (1), 2690, 2022 | 29 | 2022 |
Spatial epitope barcoding reveals clonal tumor patch behaviors X Rovira-Clavé, AP Drainas, S Jiang, Y Bai, M Baron, B Zhu, AE Dallas, ... Cancer Cell 40 (11), 1423-1439. e11, 2022 | 23 | 2022 |
Genome-wide screens implicate loss of cullin ring ligase 3 in persistent proliferation and genome instability in TP53-deficient cells AP Drainas, RA Lambuta, I Ivanova, Ö Serçin, I Sarropoulos, ML Smith, ... Cell Reports 31 (1), 2020 | 23 | 2020 |
Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability D Achuthankutty, RS Thakur, P Haahr, S Hoffmann, AP Drainas, ... Journal of Cell Biology 218 (12), 3943-3953, 2019 | 15 | 2019 |
A multiplexed in vivo approach to identify driver genes in small cell lung cancer MC Lee, H Cai, CW Murray, C Li, YT Shue, L Andrejka, AL He, ... Cell reports 42 (1), 2023 | 14 | 2023 |
Crosstalk between small-cell lung cancer cells and astrocytes mimics brain development to promote brain metastasis F Qu, SC Brough, W Michno, CJ Madubata, GG Hartmann, A Puno, ... Nature Cell Biology 25 (10), 1506-1519, 2023 | 7 | 2023 |
RB depletion is required for the continuous growth of tumors initiated by loss of RB A Doan, J Arand, D Gong, AP Drainas, YT Shue, MC Lee, S Zhang, ... Plos Genetics 17 (12), e1009941, 2021 | 5 | 2021 |
Neuronal mimicry generates an ecosystem critical for brain metastatic growth of SCLC F Qu, S Cao, W Michno, CJ Madubata, A Puno, AP Drainas, MC Lee, ... Biorxiv, 2021.08. 10.455426, 2021 | 4 | 2021 |
Elucidation of 4-Hydroxybenzoic Acid Catabolic Pathways in Pseudarthrobacter phenanthrenivorans Sphe3 E Tsagogiannis, S Asimakoula, AP Drainas, O Marinakos, VI Boti, ... International Journal of Molecular Sciences 25 (2), 843, 2024 | 1 | 2024 |
Visualizing intratumoural heterogeneity with EpicMIBI AP Drainas Nature Reviews Cancer 23 (6), 347-347, 2023 | 1 | 2023 |
Highly scalable multiplex serology by mass spectrometry analysis of beads AP Drainas, X Rovira-Clavé | | 2024 |
IGF2 is essential for tumor initiating cell activity in human colorectal cancer TD Dubash, C Siegl, SM Dieter, J Weischenfeldt, AP Drainas, ... Cancer Research 77 (13_Supplement), 2893-2893, 2017 | | 2017 |