| Site-specific conjugation of a cytotoxic drug to an antibody improves the therapeutic index JR Junutula, H Raab, S Clark, S Bhakta, DD Leipold, S Weir, Y Chen, ... Nature biotechnology 26 (8), 925-932, 2008 | 1484 | 2008 |
| Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates BQ Shen, K Xu, L Liu, H Raab, S Bhakta, M Kenrick, KL Parsons-Reponte, ... Nature biotechnology 30 (2), 184-189, 2012 | 1080 | 2012 |
| Cysteine engineered antibodies and conjugates CW Eigenbrot, JR Junutula, H Lowman, HE Raab, R Vandlen US Patent 7,521,541, 2009 | 812 | 2009 |
| Site-specific antibody drug conjugates for cancer therapy S Panowski, S Bhakta, H Raab, P Polakis, JR Junutula MAbs 6 (1), 34-45, 2014 | 723 | 2014 |
| Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking M Larance, G Ramm, J Stockli, EM van Dam, S Winata, V Wasinger, ... Journal of Biological Chemistry 280 (45), 37803-37813, 2005 | 485 | 2005 |
| Engineered thio-trastuzumab-DM1 conjugate with an improved therapeutic index to target human epidermal growth factor receptor 2–positive breast cancer JR Junutula, KM Flagella, RA Graham, KL Parsons, E Ha, H Raab, ... Clinical cancer research 16 (19), 4769-4778, 2010 | 343 | 2010 |
| Therapeutic potential of an anti-CD79b antibody–drug conjugate, anti–CD79b-vc-MMAE, for the treatment of non-Hodgkin lymphoma D Dornan, F Bennett, Y Chen, M Dennis, D Eaton, K Elkins, D French, ... Blood, The Journal of the American Society of Hematology 114 (13), 2721-2729, 2009 | 306 | 2009 |
| Rapid identification of reactive cysteine residues for site-specific labeling of antibody-Fabs JR Junutula, S Bhakta, H Raab, KE Ervin, C Eigenbrot, R Vandlen, ... Journal of immunological methods 332 (1-2), 41-52, 2008 | 231 | 2008 |
| Rab14 is involved in membrane trafficking between the Golgi complex and endosomes JR Junutula, AM De Maziére, AA Peden, KE Ervin, RJ Advani, ... Molecular biology of the cell 15 (5), 2218-2229, 2004 | 218 | 2004 |
| Cysteine engineered anti-MUC16 antibodies and antibody drug conjugates JR Junutula, W Mallet US Patent 7,723,485, 2010 | 197 | 2010 |
| Rab14 is critical for maintenance of Mycobacterium tuberculosis phagosome maturation arrest GB Kyei, I Vergne, J Chua, E Roberts, J Harris, JR Junutula, V Deretic The EMBO journal 25 (22), 5250-5259, 2006 | 195 | 2006 |
| Characterization of intact antibody–drug conjugates from plasma/serum in vivo by affinity capture capillary liquid chromatography–mass spectrometry K Xu, L Liu, OM Saad, J Baudys, L Williams, D Leipold, B Shen, H Raab, ... Analytical biochemistry 412 (1), 56-66, 2011 | 189 | 2011 |
| Cysteine engineered antibodies and conjugates CW Eigenbrot, JR Junutula, H Lowman, HE Raab, R Vandlen US Patent 7,855,275, 2010 | 179 | 2010 |
| Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase R Jin, JR Junutula, HT Matern, KE Ervin, RH Scheller, AT Brunger The EMBO journal 24 (12), 2064-2074, 2005 | 178 | 2005 |
| Rab40b regulates trafficking of MMP2 and MMP9 during invadopodia formation and invasion of breast cancer cells A Jacob, J Jing, J Lee, P Schedin, SM Gilbert, AA Peden, JR Junutula, ... Journal of cell science 126 (20), 4647-4658, 2013 | 162 | 2013 |
| Human ACE2 receptor polymorphisms predict SARS-CoV-2 susceptibility EW Stawiski, D Diwanji, K Suryamohan, R Gupta, FA Fellouse, ... BioRxiv, 2020.04. 07.024752, 2020 | 150 | 2020 |
| Site-specifically 89Zr-labeled monoclonal antibodies for ImmunoPET JN Tinianow, HS Gill, A Ogasawara, JE Flores, AN Vanderbilt, E Luis, ... Nuclear medicine and biology 37 (3), 289-297, 2010 | 148 | 2010 |
| Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2 K Suryamohan, D Diwanji, EW Stawiski, R Gupta, S Miersch, J Liu, ... Communications biology 4 (1), 475, 2021 | 143 | 2021 |
| Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex S Fukai, HT Matern, JR Jagath, RH Scheller, AT Brunger The EMBO journal, 2003 | 138 | 2003 |
| Decoupling stability and release in disulfide bonds with antibody-small molecule conjugates GD Rosario Chemical Science 8 (1), 366-370, 2017 | 128 | 2017 |
