Combined anti‐PD‐1 and anti‐CTLA‐4 checkpoint blockade: Treatment of melanoma and immune mechanisms of action ZN Willsmore, BGT Coumbe, S Crescioli, S Reci, A Gupta, RJ Harris, ... European Journal of Immunology 51 (3), 544-556, 2021 | 151 | 2021 |
B cells in patients with melanoma: implications for treatment with checkpoint inhibitor antibodies ZN Willsmore, RJ Harris, S Crescioli, K Hussein, H Kakkassery, D Thapa, ... Frontiers in Immunology 11, 622442, 2021 | 63 | 2021 |
Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes HJ Bax, J Chauhan, C Stavraka, A Santaolalla, G Osborn, A Khiabany, ... British Journal of Cancer 128 (2), 342-353, 2023 | 38 | 2023 |
Basophils from cancer patients respond to immune stimuli and predict clinical outcome HJ Bax, J Chauhan, C Stavraka, A Khiabany, M Nakamura, G Pellizzari, ... Cells 9 (7), 1631, 2020 | 33 | 2020 |
IgE antibodies against cancer: efficacy and safety J Chauhan, AJ McCraw, M Nakamura, G Osborn, HS Sow, VF Cox, ... Antibodies 9 (4), 55, 2020 | 28 | 2020 |
Insights from IgE immune surveillance in allergy and cancer for anti-tumour IgE treatments AJ McCraw, J Chauhan, HJ Bax, C Stavraka, G Osborn, M Grandits, ... Cancers 13 (17), 4460, 2021 | 27 | 2021 |
Abstract CT141: Phase 1 trial of MOv18, a first-in-class IgE antibody therapy for cancer J Spicer, B Basu, A Montes, U Banerji, R Kristeleit, GJ Veal, C Corrigan, ... Cancer research 80 (16_Supplement), CT141-CT141, 2020 | 24 | 2020 |
Clinical and translational significance of basophils in patients with cancer J Chauhan, C Stavraka, M Grandits, LCGF Palhares, DH Josephs, ... Cells 11 (3), 438, 2022 | 23 | 2022 |
IgE activates monocytes from cancer patients to acquire a pro-inflammatory phenotype M Nakamura, EA Souri, G Osborn, R Laddach, J Chauhan, C Stavraka, ... Cancers 12 (11), 3376, 2020 | 23 | 2020 |
Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4 J Chauhan, M Grandits, LCGF Palhares, S Mele, M Nakamura, ... Nature communications 14 (1), 2192, 2023 | 19 | 2023 |
Enriched circulating and tumor-resident TGF-β+ regulatory B cells in patients with melanoma promote FOXP3+ Tregs RJ Harris, Z Willsmore, R Laddach, S Crescioli, J Chauhan, A Cheung, ... Oncoimmunology 11 (1), 2104426, 2022 | 18 | 2022 |
B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma S Crescioli, I Correa, J Ng, ZN Willsmore, R Laddach, A Chenoweth, ... Nature communications 14 (1), 3378, 2023 | 13 | 2023 |
Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial J Spicer, B Basu, A Montes, U Banerji, R Kristeleit, R Miller, GJ Veal, ... Nature Communications 14 (1), 4180, 2023 | 9 | 2023 |
Innate stimulation of B cells ex vivo enhances antibody secretion and identifies tumour-reactive antibodies from cancer patients P Karagiannis, I Correa, J Chauhan, A Cheung, D Dominguez-Rodriguez, ... Clinical and Experimental Immunology 207 (1), 84-94, 2022 | 6 | 2022 |
In vivo trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart F Man, A Koers, P Karagiannis, DH Josephs, HJ Bax, AE Gilbert, ... Oncoimmunology 10 (1), 1966970, 2021 | 3 | 2021 |
Chondroitin Sulfate Proteoglycan 4 (CSPG4) as an Emerging Target for Immunotherapy to Treat Melanoma X Chen, S Habib, M Alexandru, J Chauhan, T Evan, JM Troka, A Rahimi, ... Cancers 16 (19), 3260, 2024 | | 2024 |
Granulocytes and mast cells in AllergoOncology—Bridging allergy to cancer: An EAACI position paper M Pascal, HJ Bax, C Bergmann, R Bianchini, M Castells, J Chauhan, ... Allergy 79 (9), 2319-2345, 2024 | | 2024 |
Protective effects of allergic diseases in COVID-19 outcomes: A retrospective cohort study in UK Biobank in the general population and in patients with cancer A Santaolalla, HJ Bax, J Chauhan, DH Josephs, M Van Hemelrijck, ... Clinical and experimental allergy: journal of the British Society for …, 2024 | | 2024 |
Allergooncology: Anti-cancer effects of an IgE antibody specific for the melanoma-associated antigen CSPG4 J Chauhan, M Grandits, L Palhares, S Mele, M Nakamura, S Crescioli, ... ALLERGY 78, 230-231, 2023 | | 2023 |
Allergooncology: Advanced melanoma is associated with distinct circulating B cell profiles enriched with immunoregulatory and autoreactive features Z Willsmore, S Crescioli, L Booth, R Laddach, R Yorke, R Harris, ... ALLERGY 78, 230-230, 2023 | | 2023 |