N-cadherin in cancer metastasis, its emerging role in haematological malignancies and potential as a therapeutic target in cancer KM Mrozik, OW Blaschuk, CM Cheong, ACW Zannettino, K Vandyke BMC cancer 18 (1), 939, 2018 | 356 | 2018 |
Dysregulation of bone remodeling by imatinib mesylate K Vandyke, S Fitter, AL Dewar, TP Hughes, ACW Zannettino Blood, The Journal of the American Society of Hematology 115 (4), 766-774, 2010 | 160 | 2010 |
A niche-dependent myeloid transcriptome signature defines dormant myeloma cells WH Khoo, G Ledergor, A Weiner, DL Roden, RL Terry, MM McDonald, ... Blood, The Journal of the American Society of Hematology 134 (1), 30-43, 2019 | 122 | 2019 |
The tyrosine kinase inhibitor dasatinib dysregulates bone remodeling through inhibition of osteoclasts in vivo K Vandyke, AL Dewar, P Diamond, S Fitter, CG Schultz, NA Sims, ... Journal of Bone and Mineral Research 25 (8), 1759-1770, 2010 | 100 | 2010 |
SAMSN1 is a tumor suppressor gene in multiple myeloma JE Noll, DR Hewett, SA Williams, K Vandyke, C Kok, LB To, ... Neoplasia 16 (7), 572-585, 2014 | 83 | 2014 |
Identification of novel EZH2 targets regulating osteogenic differentiation in mesenchymal stem cells S Hemming, D Cakouros, K Vandyke, MJ Davis, ACW Zannettino, ... Stem cells and development 25 (12), 909-921, 2016 | 79 | 2016 |
Suppression of PDGF-induced PI3 kinase activity by imatinib promotes adipogenesis and adiponectin secretion S Fitter, K Vandyke, S Gronthos, ACW Zannettino Journal of molecular endocrinology 48 (3), 229-240, 2012 | 77 | 2012 |
Clodronate-liposome mediated macrophage depletion abrogates multiple myeloma tumor establishment in vivo KS Opperman, K Vandyke, KC Clark, EA Coulter, DR Hewett, KM Mrozik, ... Neoplasia 21 (8), 777-787, 2019 | 70 | 2019 |
EZH2 deletion in early mesenchyme compromises postnatal bone microarchitecture and structural integrity and accelerates remodeling S Hemming, D Cakouros, J Codrington, K Vandyke, A Arthur, ... The FASEB Journal 31 (3), 1011-1027, 2017 | 62 | 2017 |
Plasma adiponectin levels are markedly elevated in imatinib-treated chronic myeloid leukemia (CML) patients: a mechanism for improved insulin sensitivity in type 2 diabetic CML … S Fitter, K Vandyke, CG Schultz, D White, TP Hughes, ACW Zannettino The Journal of Clinical Endocrinology & Metabolism 95 (8), 3763-3767, 2010 | 61 | 2010 |
Therapeutic concentrations of dasatinib inhibit in vitro osteoclastogenesis K Vandyke, AL Dewar, AN Farrugia, S Fitter, L Bik To, TP Hughes, ... Leukemia 23 (5), 994-997, 2009 | 60 | 2009 |
PTTG1 expression is associated with hyperproliferative disease and poor prognosis in multiple myeloma JE Noll, K Vandyke, DR Hewett, KM Mrozik, RJ Bala, SA Williams, CH Kok, ... Journal of hematology & oncology 8, 1-16, 2015 | 56 | 2015 |
HIF-2α Promotes Dissemination of Plasma Cells in Multiple Myeloma by Regulating CXCL12/CXCR4 and CCR1 K Vandyke, MN Zeissig, DR Hewett, SK Martin, KM Mrozik, CM Cheong, ... Cancer Research 77 (20), 5452-5463, 2017 | 55 | 2017 |
EphB4 enhances the process of endochondral ossification and inhibits remodeling during bone fracture repair A Arthur, RA Panagopoulos, L Cooper, D Menicanin, IH Parkinson, ... Journal of Bone and Mineral Research 28 (4), 926-935, 2013 | 53 | 2013 |
Immunomodulatory properties of induced pluripotent stem cell‐derived mesenchymal cells J Ng, K Hynes, G White, KN Sivanathan, K Vandyke, PM Bartold, ... Journal of Cellular Biochemistry 117 (12), 2844-2853, 2016 | 51 | 2016 |
Imatinib mesylate causes growth plate closure in vivo K Vandyke, AL Dewar, S Fitter, D Menicanin, LB To, TP Hughes, ... Leukemia 23 (11), 2155-2159, 2009 | 50 | 2009 |
Sphingosine kinase 2 inhibition synergises with bortezomib to target myeloma by enhancing endoplasmic reticulum stress CT Wallington-Beddoe, MK Bennett, K Vandyke, L Davies, JR Zebol, ... Oncotarget 8 (27), 43602, 2017 | 45 | 2017 |
Circulating N‐cadherin levels are a negative prognostic indicator in patients with multiple myeloma K Vandyke, AWS Chow, SA Williams, LB To, ACW Zannettino British journal of haematology 161 (4), 499-507, 2013 | 44 | 2013 |
Therapeutic targeting of N‐cadherin is an effective treatment for multiple myeloma KM Mrozik, CM Cheong, D Hewett, AWS Chow, OW Blaschuk, ... British journal of haematology 171 (3), 387-399, 2015 | 43 | 2015 |
Tetraspanin 7 (TSPAN7) expression is upregulated in multiple myeloma patients and inhibits myeloma tumour development in vivo CM Cheong, AWS Chow, S Fitter, DR Hewett, SK Martin, SA Williams, ... Experimental Cell Research 332 (1), 24-38, 2015 | 42 | 2015 |