Highly prevalent colorectal cancer-infiltrating LAP+ Foxp3− T cells exhibit more potent immunosuppressive activity than Foxp3+ regulatory T cells M Scurr, K Ladell, M Besneux, A Christian, T Hockey, K Smart, ... Mucosal immunology 7 (2), 428-439, 2014 | 159 | 2014 |
Human leukocyte antigen (HLA) class II peptide flanking residues tune the immunogenicity of a human tumor-derived epitope BJ MacLachlan, G Dolton, A Papakyriakou, A Greenshields-Watson, ... Journal of Biological Chemistry 294 (52), 20246-20258, 2019 | 14 | 2019 |
NG-641: An oncolytic T-SIGn virus targeting cancer-associated fibroblasts in the stromal microenvironment of human carcinomas BR Champion, M Besneux, M Patsalidou, A Silva, M Zonca, N Marino, ... Cancer Research 79 (13_Supplement), 5013-5013, 2019 | 14 | 2019 |
The nature of the human T cell response to the cancer antigen 5T4 is determined by the balance of regulatory and inflammatory T cells of the same antigen-specificity … M Besneux, A Greenshields-Watson, MJ Scurr, BJ MacLachlan, ... Cancer Immunology, Immunotherapy 68, 247-256, 2019 | 13 | 2019 |
Developing tumor-localized, combination immunotherapies BR Champion, N Rasiah, S Illingworth, M Besneux, R Lear, D Plumb, ... Cancer Research 76 (14_Supplement), 4875-4875, 2016 | 6 | 2016 |
Elucidating the role of regulatory T cells in colorectal cancer progression M Besneux Cardiff University, 2015 | 2 | 2015 |
Oncolytic virus and method B Champion, ACN Bromley, M Besneux US Patent 11,142,580, 2021 | 1 | 2021 |
NG-348: a novel oncolytic virus designed to mediate anti-tumour activity via the potent and selective polyclonal activation of tumor-infiltrating T-cells BR Champion, M Besneux, N Marino, D Plumb, P Kodialbail, S Illingworth, ... Cancer Research 77 (13_Supplement), 5098-5098, 2017 | 1 | 2017 |
821 The potential clinical usage of Fc-optimized anti-CCR8 therapeutic antibodies as a monotherapy or combined with other promising immune-modulating agents beyond PD-1/L1 S Dai, W Huang, L Yan, S Peng, S Zhou, Z Yuan, C Wang, CC Chou, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | | 2022 |
Arming the oncolytic virus enadenotucirev (EnAd) to generate enhanced locally-acting immunotherapies for cancer BR Champion, N Rasiah, S Illingworth, H Calderon, M Besneux, R Lear, ... Journal for ImmunoTherapy of Cancer 3 (2), 1-2, 2015 | | 2015 |
Breaking down barriers to effective anti-tumour immunity A Gallimore, M Scurr, M Besneux, A Bloom, E Jones, E Colbeck, ... IMMUNOLOGY 140, 1-1, 2013 | | 2013 |
Immunotherapy: identification of 5T4 epitopes for individual colorectal cancer patients M Besneux, M Scurr, A Gallimore, A Godkin IMMUNOLOGY 140, 71-71, 2013 | | 2013 |